Cryo-EM structure of Cas1:Cas2-DEDDh:half-site integration complex

Genome expansion by a CRISPR trimmer-integrase.

Cas1:Cas2-DEDDh:half-site integration complex

National Science Foundation (NSF, United States)

CRISPR, integrase, CRISPR adaptation module, PAM, prespacer, exonuclease, DNA binding protein-DNA complex, enzyme, ribonucleoprotein