SARS-CoV-2 main protease in complex with covalent inhibitor

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

Alkyne as a Latent Warhead to Covalently Target SARS-CoV-2 Main Protease.

3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase

Severe acute respiratory syndrome coronavirus 2

National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)

SARS-CoV-2 main protease, Protease, Non-Structural Protein, Covalent Inhibitor, VIRAL PROTEIN, Hydrolase-Inhibitor complex