Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor

Allosteric Competitive Inhibitors of the Glucose-1-Phosphate Thymidylyltransferase (Rmla) from Pseudomonas Aeruginosa.

GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. SOME RESIDUES AT THE N-TERMINI ARE DISORDERED AND HAVE BEEN OMITTED FROM THE MODEL. RESIDUES D192-D197 WERE NOT CLEARLY DEFINED AND HAVE BEEN OMITTED FROM THE MODEL. THE BOUND COMPOUND HAS BEEN MODELLED IN THE PREDOMINANT CONFORMATION. SEVERAL RESIDUES HAVE BEEN MODELLED IN WITH ALTERNATE CONFORMATIONS.

GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE (E.C.2.7.7.24)

THYMIDYLYL, TRANSFERASE, ALLOSTERIC, INHIBITOR, PSEUDOMONAS