Structure of full-length amyloidogenic immunoglobulin light chain H9 in complex with 6-methyl-2-(2-((1E,2E)-3-(2-nitrophenyl)allylidene)hydrazineyl)pyrimidin-4-ol

Crystal Structures of Diaryl Hydrazone and Sulfone Stabilizers in Complex with an Amyloidogenic Light Chain Reveal an Alternate Ligand-Binding Cavity

20% PEG3350, 0.2 M potassium phosphate monobasic, 4 degrees C

National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI)

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

light chain, amyloidosis, stabilizer, IMMUNE SYSTEM