Human Carbonic Anhydrase I complexed with a two-prong inhibitor

Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with two-prong inhibitors reveal the molecular basis of high affinity.

Carbonic anhydrase I, Carbonate dehydratase I, CA-I

Tris-sulfate, MES, PEG 3350, NaCl, pH 6.4, VAPOR DIFFUSION, HANGING DROP, temperature 277K

The biological unit is a monomer. There are 2 biological units in the asymmetric unit