Structure of glycosylated glutaminyl cyclase from Drosophila melanogaster

Crystal Structures of Glutaminyl Cyclases (QCs) from Drosophila melanogaster Reveal Active Site Conservation between Insect and Mammalian QCs.

glutaminyl-peptide cyclotransferase, GH11174p

10% PEG35000, 2 mM PQ50, 0.1 M Tris, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 294K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : REFINED INDIVIDUALLY

alpha/beta hydrolase, pGlu formation, PE, Alzheimer's Disease, pyroglutamate, pGlu-amyloid, glycosylation, TRANSFERASE, HYDROLASE