First pair of Fibronectin type III domains and part of the connecting segment of the integrin beta4

Structural basis of the interaction between integrin alpha6beta4 and plectin at the hemidesmosomes

Fibronectin type-III, residues 1126-1355

0.1M Tris-HCl, 0.3M NaCl, 24% PEG 200, pH 7.5, VAPOR DIFFUSION, temperature 298K

Similar fragment lacking the connecting segment

STRUCTURE OF A SIMILAR FRAGMENT OF INTEGRIN BETA4 IN COMPLEX WITH PLECTIN

STRUCTURE AT 2.04A OF AN EQUIVALENT FRAGMENT OF INTEGRIN BETA4

THE SEQUENCE IS BASED ON REFERENCE 2 IN THE DATABASE, ITB4_HUMAN.

The monomeric form is believed to be the biological unit.

INTEGRIN, HEMIDESMOSOME, CELL ADHESION, CARCINOMA, EPIDERMOLYSIS BULLOSA, Alternative splicing, Disease mutation, Glycoprotein, Membrane, Phosphoprotein, Polymorphism, Receptor, Transmembrane