Design, synthesis, biological evaluation and crystal structure determination of dual modulators of carbonic anhydrases and estrogen receptors.

ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1

NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2

National Institutes of Health/National Cancer Institute (NIH/NCI)

U VALUES : WITH TLS ADDED HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : RESIDUAL ONLY

ER-alpha, ligand complex, carbonic anhydrase, DNA BINDING PROTEIN