A TOPRIM domain in the crystal structure of the catalytic core of Escherichia coli primase confirms a structural link to DNA topoisomerases.

For the refinement the data from lambda 1 (0.98636) were taken.

PEG 4000, DTT, Tris/HCl, sodium acetate, pH 8.3, VAPOR DIFFUSION, HANGING DROP, temperature 293K

Engh & Huber,
Hendrickson W.A. and Konnert J.H.

The biological assembly is a monomer constructed from either chain A, B, C, D or E.

Toprim domain, Rossmann fold, TRANSFERASE