Structure of Human DNA Polymerase Iota complexed with N2-ethylguanine

Lesion bypass of N2-ethylguanine by human DNA polymerase iota.

MBP-DNA pol Iota Fusion with PreScission Protease cleavage site

12-15% PEG MME 5000, 0.2-0.4M Ammonium Sulfate, 0.1M MES, pH 6.5, VAPOR DIFFUSION, HANGING DROP, temperature 277.15K

Structure of DNA polymerase iota with template guanine and incoming dCTP

Binary structure of DNA polymerase iota with template guanine

A self-annealing oligonucletoide was synthesized by Midland Certified Reagents containing N2-ethylgaunine using phosphoramidite chemistry

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

DNA polymerase iota (E.C.2.7.7.7)/DNA complex

DNA pol iota, lesion bypass, N2-ethylguanine, DNA damage, DNA repair, DNA replication, DNA synthesis, DNA-binding, DNA-directed DNA polymerase, Magnesium, Metal-binding, Mutator protein, Nucleotidyltransferase, Nucleus, Schiff base, Transferase, TRANSFERASE-DNA COMPLEX