Crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP-tail determined at 2.7 angstrom resolution

Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite.

2.5 mM TRAP-tail, 0.5% n-dodecyl-beta-D-maltoside, 50 mM cacodylic acid pH 6.0, 20% PEG 2000, VAPOR DIFFUSION, SITTING DROP, temperature 298K

Structural Genomics of Pathogenic Protozoa Consortium

Fructose-bisphosphate aldolase from Plasmodium falciparum

Fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP-tail, 2.4 angstrom resolution

Synthetic peptide with the sequence based on PbTRAP protein from Plasmodium berghei, UNP entry P90573, P90573_PLABE, residues 601-606

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

Fructose-bisphosphate aldolase (E.C.4.1.2.13), PbTRAP

Aldolase, Invasion machinery, Plasmodium falciparum, Structural Genomics, PSI, Protein Structure Initiative, Structural Genomics of Pathogenic Protozoa Consortium, SGPP, LYASE