Murine inos dimer with inhibitor 4-MAP bound

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.

Inducible NO synthase, Inducible NOS, iNOS, NOS type II, Macrophage NOS, MAC-NOS

50 mM MES pH 5.3, 25% LITHIUM SULFATE, 5% B-OCTYL-GLUCODISE, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K

Nitric oxide synthase, inducible (E.C.1.14.13.39)

nitric oxide sythase, oxygenase domain, dimer, isozyme-specific inhibitors, Calmodulin-binding, FAD, FMN, Heme, Iron, Metal-binding, NADP, Oxidoreductase, Polymorphism, Zinc