The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase

Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase alpha-primase.

0.96 M sodium malonate, pH 6.0, VAPOR DIFFUSION, HANGING DROP, temperature 291K

Large T antigen, DNA polymerase alpha subunit B
replication initiation, Hydrolase-DNA binding complex, Hydrolase-DNA binding Protein complex