Crystal structure of human butyrylcholinesterase in complex with N-((1-benzylpiperidin-3-yl)methyl)-N-methylnaphthalene-2-sulfonamide

Development of an in-vivo active reversible butyrylcholinesterase inhibitor.

NAG A 610 HAS WRONG CHIRALITY AT ATOM C1

NAG B 611 HAS WRONG CHIRALITY AT ATOM C1

Acylcholine acylhydrolase,Butyrylcholine esterase,Choline esterase II,Pseudocholinesterase

0.2 M ammonium acetate, 12% polyethylene glycol 4000.

human butyrylcholinesterase, AD, alzheimer disease, sulfonamide, hydrolase