Crystal structure the Escherichia coli Cas1-Cas2 complex bound to protospacer DNA with splayed ends

Foreign DNA capture during CRISPR-Cas adaptive immunity.

100 mM sodium citrate tribasic pH 5.6, 200 mM sodium acetate and 8% PEG 8000 (w/v)

4P6I contains the same protein complex in Apo form.

CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2/DNA Complex

Adaptive Immunity, CRISPR-Associated Proteins, CRISPR-Cas Systems, Clustered Regularly Interspaced Short Palindromic Repeats, Integrases, Endodeoxyribonucleases, Endonucleases, DNA binding protein, Hydrolase-DNA complex