Crystal Structure of Cas-DNA-PAM complex

Structural and Mechanistic Basis of PAM-Dependent Spacer Acquisition in CRISPR-Cas Systems.

50mM Na cacodylate,0.9mM spermine,18mM Magnesium chloride, 1.8mM Cobalt chloride, 9% isopropanol

CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2/DNA Complex

protein-DNA complex, HYDROLASE-DNA complex