Cryo-EM structure of human Ptch1 and ShhN complex

Structural basis for the recognition of Sonic Hedgehog by human Patched1.

SHH,HHG-1,Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains,ShhNC

Escherichia coli 'BL21-Gold(DE3)pLysS AG'

National Science Foundation (NSF, China)

National Basic Research Program of China (973 Program)

Protein patched homolog 1, Sonic hedgehog protein