Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with TS-II-224

4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID

N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE

Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors.

10% PEG 8000, 5% iso-propanol, 0.1M HEPES 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K

( CHAIN A AND ( RESID 44:252 OR RESID 474:492 ) )

( CHAIN C AND ( RESID 44:252 OR RESID 474:492 ) )

HIV-1 gp120, clade A/E, CD4 mimic, TS-II-224, VIRAL PROTEIN-INHIBITOR complex