CRYSTAL STRUCTURES OF BACILLUS SUBTILIS PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE: MOLECULAR BASIS OF ALLOSTERIC INHIBITION AND ACTIVATION.

PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER

Structural basis for the function of Bacillus subtilis phosphoribosyl-pyrophosphate synthetase.

Overexpression of the B. Subtilis Phosphoribosylpyrophosphate Synthetase and Crystallization of the Free Enzyme and its Substrate-Effector Complexes

PROTEIN (PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE)

Sodium citrate, Hepes, alpha,beta-methylene ADP, Magnesium chloride, beta- octylglucoside , pH 8.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K

Complex with sulfate ions bound in the active and allosteric site

SELECTED IN CONSISTENCE WITH THE R-FREE DATA FOR STRUCTURE ID CODE 1DKR

PHOSPHORIBOSYLPYROPHOSPHATE SYNTHETASE (E.C.2.7.6.1)

OPEN ALPHA-BETA STRUCTURE, DOMAIN DUPLICATION, PHOSPHORIBOSYLTRANSFERASE TYPE I FOLD, TRANSFERASE