Crystal structure of the Rab11 GEF SH3BP5 bound to nucleotide free Rab11A

2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.

Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5.

SH3BP-5,SH3 domain-binding protein that preferentially associates with BTK

23% PEG-3350, 200 mM NaCl, 100 mM Bis Tris pH-6.5

Natural Sciences and Engineering Research Council (NSERC, Canada)

Ras-related protein Rab-11A, SH3 domain-binding protein 5

Rab GTPase, Guanine nucleotide exchange factor, membrane trafficking, PROTEIN TRANSPORT, SIGNALING PROTEIN-PROTEIN TRANSPORT complex

(chain 'B' and (resid 41 through 45 or resid 47 through 53 or resid 55 through 61 or resid 63 through 88 or resid 90 through 92 or resid 94 through 95 or resid 97 through 101 or resid 103 through 116 or resid 118 through 123 or resid 125 through 192 or resid 194 through 201 or resid 203 through 208 or resid 210 through 216 or resid 218 through 222 or resid 224 through 225 or resid 227 through 239 or resid 241 through 243 or resid 245 through 251 or resid 253 through 260))

(chain 'E' and (resid 41 through 45 or resid 47 through 53 or resid 55 through 61 or resid 63 through 88 or resid 90 through 92 or resid 94 through 95 or resid 97 through 101 or resid 103 through 116 or resid 118 through 123 or resid 125 through 192 or resid 194 through 201 or resid 203 through 208 or resid 210 through 216 or resid 218 through 222 or resid 224 through 225 or resid 227 through 239 or resid 241 through 243 or resid 245 through 251 or resid 253 through 257 or (resid 258 through 260 and (name N or name CA or name C or name O or name CB ))))