Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
type: datablock
references: doi:10.2210/pdb8di4/pdb
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8DI4
type: atom sites
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entry: entry
atom sites.entry id: 8DI4
atom sites.fract transf matrix11: 0.020109
atom sites.fract transf matrix12: 0.000000
atom sites.fract transf matrix13: 0.000000
atom sites.fract transf matrix21: 0.000000
atom sites.fract transf matrix22: 0.012291
atom sites.fract transf matrix23: 0.000000
atom sites.fract transf matrix31: 0.000000
atom sites.fract transf matrix32: 0.000000
atom sites.fract transf matrix33: 0.006339
atom sites.fract transf vector1: 0.00000
atom sites.fract transf vector2: 0.00000
atom sites.fract transf vector3: 0.00000

http://rdf.wwpdb.org/pdb/8DI4/atom_type/C
type: atom type
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
atom type.symbol: C

MG
type: atom type
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
atom type.symbol: MG

http://rdf.wwpdb.org/pdb/8DI4/atom_type/N
type: atom type
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
atom type.symbol: N

http://rdf.wwpdb.org/pdb/8DI4/atom_type/O
type: atom type
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
atom type.symbol: O

http://rdf.wwpdb.org/pdb/8DI4/atom_type/S
type: atom type
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
atom type.symbol: S

ZN
type: atom type
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
atom type.symbol: ZN

http://rdf.wwpdb.org/pdb/8DI4/audit_author/1
type: audit author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
audit author.pdbx ordinal: 1
audit author.identifier ORCID: 0000-0003-4947-4410
audit author.name: Hayes, R.P.
link to orcid: orcid:0000-0003-4947-4410

orcid:0000-0003-4947-4410

http://rdf.wwpdb.org/pdb/8DI4/audit_author/2
type: audit author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
audit author.pdbx ordinal: 2
audit author.name: Yan, Y.

mmcif pdbx.dic,5.366
type: audit conform
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
audit conform.dict name: mmcif_pdbx.dic
audit conform.dict version: 5.366
audit conform.dict location: http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic

8DI4
type: cell
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entry: entry
cell.entry id: 8DI4
cell.z PDB: 8
cell.angle alpha: 90.000
cell.angle beta: 90.000
cell.angle gamma: 90.000
cell.length a: 49.730
cell.length b: 81.360
cell.length c: 157.749

ALA
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: ALA
link to chem comp: ALA
chem comp.formula: C3 H7 N O2
chem comp.formula weight: 89.093
chem comp.mon nstd flag: y
chem comp.name: ALANINE
chem comp.type: L-peptide linking
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referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/45

ARG
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: ARG
link to chem comp: ARG
chem comp.formula: C6 H15 N4 O2 1
chem comp.formula weight: 175.209
chem comp.mon nstd flag: y
chem comp.name: ARGININE
chem comp.type: L-peptide linking
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referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/38

ASN
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: ASN
link to chem comp: ASN
chem comp.formula: C4 H8 N2 O3
chem comp.formula weight: 132.118
chem comp.mon nstd flag: y
chem comp.name: ASPARAGINE
chem comp.type: L-peptide linking

ASP
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: ASP
link to chem comp: ASP
chem comp.formula: C4 H7 N O4
chem comp.formula weight: 133.103
chem comp.mon nstd flag: y
chem comp.name: ASPARTIC ACID
chem comp.type: L-peptide linking
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referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/48

CYS
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: CYS
link to chem comp: CYS
chem comp.formula: C3 H7 N O2 S
chem comp.formula weight: 121.158
chem comp.mon nstd flag: y
chem comp.name: CYSTEINE
chem comp.type: L-peptide linking

GLN
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: GLN
link to chem comp: GLN
chem comp.formula: C5 H10 N2 O3
chem comp.formula weight: 146.144
chem comp.mon nstd flag: y
chem comp.name: GLUTAMINE
chem comp.type: L-peptide linking
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referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/18
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/41

GLU
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: GLU
link to chem comp: GLU
chem comp.formula: C5 H9 N O4
chem comp.formula weight: 147.129
chem comp.mon nstd flag: y
chem comp.name: GLUTAMIC ACID
chem comp.type: L-peptide linking
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/3
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/4
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/5
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/6
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referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/47

GLY
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: GLY
link to chem comp: GLY
chem comp.formula: C2 H5 N O2
chem comp.formula weight: 75.067
chem comp.mon nstd flag: y
chem comp.name: GLYCINE
chem comp.type: peptide linking
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referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/26

HIS
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: HIS
link to chem comp: HIS
chem comp.formula: C6 H10 N3 O2 1
chem comp.formula weight: 156.162
chem comp.mon nstd flag: y
chem comp.name: HISTIDINE
chem comp.type: L-peptide linking
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/3

HOH
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: HOH
link to chem comp: HOH
chem comp.formula: H2 O
chem comp.formula weight: 18.015
chem comp.name: WATER
chem comp.type: non-polymer

ILE
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: ILE
link to chem comp: ILE
chem comp.formula: C6 H13 N O2
chem comp.formula weight: 131.173
chem comp.mon nstd flag: y
chem comp.name: ISOLEUCINE
chem comp.type: L-peptide linking
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referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/34

LEU
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: LEU
link to chem comp: LEU
chem comp.formula: C6 H13 N O2
chem comp.formula weight: 131.173
chem comp.mon nstd flag: y
chem comp.name: LEUCINE
chem comp.type: L-peptide linking

LYS
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: LYS
link to chem comp: LYS
chem comp.formula: C6 H15 N2 O2 1
chem comp.formula weight: 147.195
chem comp.mon nstd flag: y
chem comp.name: LYSINE
chem comp.type: L-peptide linking
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referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/52
referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/53
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/19
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/42

MET
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: MET
link to chem comp: MET
chem comp.formula: C5 H11 N O2 S
chem comp.formula weight: 149.211
chem comp.mon nstd flag: y
chem comp.name: METHIONINE
chem comp.type: L-peptide linking
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/4

MG
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: MG
link to chem comp: MG
chem comp.formula: Mg 2
chem comp.formula weight: 24.305
chem comp.name: MAGNESIUM ION
chem comp.type: non-polymer

PHE
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: PHE
link to chem comp: PHE
chem comp.formula: C9 H11 N O2
chem comp.formula weight: 165.189
chem comp.mon nstd flag: y
chem comp.name: PHENYLALANINE
chem comp.type: L-peptide linking

PRO
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: PRO
link to chem comp: PRO
chem comp.formula: C5 H9 N O2
chem comp.formula weight: 115.130
chem comp.mon nstd flag: y
chem comp.name: PROLINE
chem comp.type: L-peptide linking
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/14
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/37

S9I
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: S9I
link to chem comp: S9I
chem comp.formula: C19 H22 N6 O S
chem comp.formula weight: 382.483
chem comp.name: 2-methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}-N-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]pyrimidin-4-amine
chem comp.type: non-polymer

SER
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: SER
link to chem comp: SER
chem comp.formula: C3 H7 N O3
chem comp.formula weight: 105.093
chem comp.mon nstd flag: y
chem comp.name: SERINE
chem comp.type: L-peptide linking
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/2
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/12
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/13
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/15
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/23
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/27
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/35
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/36
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/38
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/46

THR
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: THR
link to chem comp: THR
chem comp.formula: C4 H9 N O3
chem comp.formula weight: 119.119
chem comp.mon nstd flag: y
chem comp.name: THREONINE
chem comp.type: L-peptide linking
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/7
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/9
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/30
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/32

TRP
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: TRP
link to chem comp: TRP
chem comp.formula: C11 H12 N2 O2
chem comp.formula weight: 204.225
chem comp.mon nstd flag: y
chem comp.name: TRYPTOPHAN
chem comp.type: L-peptide linking
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/10
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/33

TYR
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: TYR
link to chem comp: TYR
chem comp.formula: C9 H11 N O3
chem comp.formula weight: 181.189
chem comp.mon nstd flag: y
chem comp.name: TYROSINE
chem comp.type: L-peptide linking

VAL
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: VAL
link to chem comp: VAL
chem comp.formula: C5 H11 N O2
chem comp.formula weight: 117.146
chem comp.mon nstd flag: y
chem comp.name: VALINE
chem comp.type: L-peptide linking
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referenced by pdbx unobs or zero occ atoms: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/2
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/16
referenced by pdbx unobs or zero occ residues: http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/39

ZN
type: chem comp
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
chem comp.id: ZN
link to chem comp: ZN
chem comp.formula: Zn 2
chem comp.formula weight: 65.409
chem comp.name: ZINC ION
chem comp.type: non-polymer

primary
type: citation
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
citation.id: primary
citation.country: US
citation.journal abbrev: J.Med.Chem.
citation.journal id ASTM: JMCMAR
citation.journal id CSD: 0151
citation.journal id ISSN: 0022-2623
citation.journal volume: 66
citation.page first: 1157
citation.page last: 1171
citation.pdbx database id DOI: 10.1021/acs.jmedchem.2c01521
citation.pdbx database id pub med: 36624931
citation.title: Discovery of MK-8189, a Highly Potent and Selective PDE10A Inhibitor for the Treatment of Schizophrenia.
citation.year: 2023
link to doi: doi:10.1021/acs.jmedchem.2c01521
link to pubmed: pubmed:36624931
references: pubmed:36624931

primary,Layton, M.E.,1
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Layton, M.E.
citation author.ordinal: 1
citation author.identifier ORCID: 0000-0002-2607-0379
link to orcid: orcid:0000-0002-2607-0379

orcid:0000-0002-2607-0379

primary,Kern, J.C.,2
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Kern, J.C.
citation author.ordinal: 2

primary,Hartingh, T.J.,3
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Hartingh, T.J.
citation author.ordinal: 3

primary,Shipe, W.D.,4
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Shipe, W.D.
citation author.ordinal: 4
citation author.identifier ORCID: 0000-0001-6555-6788
link to orcid: orcid:0000-0001-6555-6788

orcid:0000-0001-6555-6788

primary,Raheem, I.,5
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Raheem, I.
citation author.ordinal: 5
citation author.identifier ORCID: 0000-0002-6769-8816
link to orcid: orcid:0000-0002-6769-8816

orcid:0000-0002-6769-8816

primary,Kandebo, M.,6
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Kandebo, M.
citation author.ordinal: 6

primary,Hayes, R.P.,7
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Hayes, R.P.
citation author.ordinal: 7

primary,Huszar, S.,8
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Huszar, S.
citation author.ordinal: 8

primary,Eddins, D.,9
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Eddins, D.
citation author.ordinal: 9

primary,Ma, B.,10
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Ma, B.
citation author.ordinal: 10

primary,Fuerst, J.,11
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Fuerst, J.
citation author.ordinal: 11

primary,Wollenberg, G.K.,12
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Wollenberg, G.K.
citation author.ordinal: 12

primary,Li, J.,13
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Li, J.
citation author.ordinal: 13

primary,Fritzen, J.,14
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Fritzen, J.
citation author.ordinal: 14

primary,McGaughey, G.B.,15
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: McGaughey, G.B.
citation author.ordinal: 15
citation author.identifier ORCID: 0000-0002-3586-965X
link to orcid: orcid:0000-0002-3586-965X

orcid:0000-0002-3586-965X

primary,Uslaner, J.M.,16
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Uslaner, J.M.
citation author.ordinal: 16
citation author.identifier ORCID: 0000-0002-8952-5940
link to orcid: orcid:0000-0002-8952-5940

orcid:0000-0002-8952-5940

primary,Smith, S.M.,17
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Smith, S.M.
citation author.ordinal: 17

primary,Coleman, P.J.,18
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Coleman, P.J.
citation author.ordinal: 18

primary,Cox, C.D.,19
type: citation author
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to citation: citation
citation author.citation id: primary
citation author.name: Cox, C.D.
citation author.ordinal: 19

8DI4,PDB
type: database 2
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
database 2.database code: 8DI4
database 2.database id: PDB
database 2.pdbx DOI: 10.2210/pdb8di4/pdb
database 2.pdbx database accession: pdb_00008di4

D 1000266735,WWPDB
type: database 2
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
database 2.database code: D_1000266735
database 2.database id: WWPDB

http://rdf.wwpdb.org/pdb/8DI4/diffrn/1
type: diffrn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to exptl crystal: http://rdf.wwpdb.org/pdb/8DI4/exptl_crystal/1
diffrn.id: 1
diffrn.ambient temp: 100
diffrn.crystal id: 1
diffrn.pdbx serial crystal experiment: N

http://rdf.wwpdb.org/pdb/8DI4/exptl_crystal/1
referenced by diffrn: http://rdf.wwpdb.org/pdb/8DI4/diffrn/1
type: exptl crystal
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
exptl crystal.id: 1
exptl crystal.density matthews: 2.01
exptl crystal.density percent sol: 38.94

http://rdf.wwpdb.org/pdb/8DI4/diffrn_detector/1
type: diffrn detector
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to diffrn: diffrn
diffrn detector.diffrn id: 1
diffrn detector.detector: CCD
diffrn detector.pdbx collection date: 2011-08-24
diffrn detector.type: ADSC QUANTUM 315

http://rdf.wwpdb.org/pdb/8DI4/diffrn_radiation/1
type: diffrn radiation
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to diffrn: diffrn
diffrn radiation.diffrn id: 1
diffrn radiation.pdbx diffrn protocol: SINGLE WAVELENGTH
diffrn radiation.pdbx monochromatic or laue m l: M
diffrn radiation.pdbx scattering type: x-ray
diffrn radiation.wavelength id: 1

http://rdf.wwpdb.org/pdb/8DI4/diffrn_radiation_wavelength/1
type: diffrn radiation wavelength
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
diffrn radiation wavelength.id: 1
diffrn radiation wavelength.wavelength: 1.000
diffrn radiation wavelength.wt: 1.0

http://rdf.wwpdb.org/pdb/8DI4/diffrn_source/1
type: diffrn source
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to diffrn: diffrn
diffrn source.diffrn id: 1
diffrn source.pdbx synchrotron beamline: 17-ID
diffrn source.pdbx synchrotron site: APS
diffrn source.pdbx wavelength list: 1.000
diffrn source.source: SYNCHROTRON
diffrn source.type: APS BEAMLINE 17-ID

http://rdf.wwpdb.org/pdb/8DI4/entity/1
type: entity
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
entity.id: 1
entity.formula weight: 39606.430
entity.pdbx description: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
entity.pdbx ec: 3.1.4.17,3.1.4.35
entity.pdbx fragment: catalytic domain residues 439-779
entity.pdbx number of molecules: 2
entity.src method: man
entity.type: polymer
link to enzyme: ec-code:3.1.4.17
link to enzyme: ec-code:3.1.4.35
referenced by struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/A
referenced by struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/B
referenced by struct ref: http://rdf.wwpdb.org/pdb/8DI4/struct_ref/1

ec-code:3.1.4.17

ec-code:3.1.4.35

http://rdf.wwpdb.org/pdb/8DI4/entity/2
type: entity
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
entity.id: 2
entity.formula weight: 65.409
entity.pdbx description: ZINC ION
entity.pdbx number of molecules: 2
entity.src method: syn
entity.type: non-polymer
referenced by struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/C
referenced by struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/F

http://rdf.wwpdb.org/pdb/8DI4/entity/3
type: entity
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
entity.id: 3
entity.formula weight: 24.305
entity.pdbx description: MAGNESIUM ION
entity.pdbx number of molecules: 2
entity.src method: syn
entity.type: non-polymer
referenced by struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/D
referenced by struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/G

http://rdf.wwpdb.org/pdb/8DI4/entity/4
type: entity
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
entity.id: 4
entity.formula weight: 382.483
entity.pdbx description: 2-methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}-N-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]pyrimidin-4-amine
entity.pdbx number of molecules: 2
entity.src method: syn
entity.type: non-polymer
referenced by struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/E
referenced by struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/H

http://rdf.wwpdb.org/pdb/8DI4/entity/5
type: entity
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
entity.id: 5
entity.formula weight: 18.015
entity.pdbx description: water
entity.pdbx number of molecules: 105
entity.src method: nat
entity.type: water
referenced by struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/I
referenced by struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/J

http://rdf.wwpdb.org/pdb/8DI4/entity_poly/1
type: entity poly
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: entity
entity poly.entity id: 1
entity poly.nstd linkage: no
entity poly.nstd monomer: no
entity poly.pdbx seq one letter code: GSHMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSVAQKAAASED
entity poly.pdbx seq one letter code can: GSHMSICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSVAQKAAASED
entity poly.pdbx strand id: A,B
entity poly.type: polypeptide(L)

1,GLY,1
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 1
entity poly seq.hetero: n

1,SER,2
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 2
entity poly seq.hetero: n

1,HIS,3
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 3
entity poly seq.hetero: n

1,MET,4
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 4
entity poly seq.hetero: n

1,SER,5
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 5
entity poly seq.hetero: n

1,ILE,6
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 6
entity poly seq.hetero: n

1,CYS,7
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 7
entity poly seq.hetero: n

1,THR,8
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 8
entity poly seq.hetero: n

1,SER,9
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 9
entity poly seq.hetero: n

1,GLU,10
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 10
entity poly seq.hetero: n

1,GLU,11
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 11
entity poly seq.hetero: n

1,TRP,12
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 12
entity poly seq.hetero: n

1,GLN,13
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 13
entity poly seq.hetero: n

1,GLY,14
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 14
entity poly seq.hetero: n

1,LEU,15
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 15
entity poly seq.hetero: n

1,MET,16
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 16
entity poly seq.hetero: n

1,GLN,17
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 17
entity poly seq.hetero: n

1,PHE,18
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 18
entity poly seq.hetero: n

1,THR,19
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 19
entity poly seq.hetero: n

1,LEU,20
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 20
entity poly seq.hetero: n

1,PRO,21
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 21
entity poly seq.hetero: n

1,VAL,22
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 22
entity poly seq.hetero: n

1,ARG,23
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 23
entity poly seq.hetero: n

1,LEU,24
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 24
entity poly seq.hetero: n

1,CYS,25
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 25
entity poly seq.hetero: n

1,LYS,26
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 26
entity poly seq.hetero: n

1,GLU,27
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 27
entity poly seq.hetero: n

1,ILE,28
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 28
entity poly seq.hetero: n

1,GLU,29
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 29
entity poly seq.hetero: n

1,LEU,30
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 30
entity poly seq.hetero: n

1,PHE,31
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 31
entity poly seq.hetero: n

1,HIS,32
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 32
entity poly seq.hetero: n

1,PHE,33
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 33
entity poly seq.hetero: n

1,ASP,34
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 34
entity poly seq.hetero: n

1,ILE,35
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 35
entity poly seq.hetero: n

1,GLY,36
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 36
entity poly seq.hetero: n

1,PRO,37
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 37
entity poly seq.hetero: n

1,PHE,38
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 38
entity poly seq.hetero: n

1,GLU,39
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 39
entity poly seq.hetero: n

1,ASN,40
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 40
entity poly seq.hetero: n

1,MET,41
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 41
entity poly seq.hetero: n

1,TRP,42
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 42
entity poly seq.hetero: n

1,PRO,43
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 43
entity poly seq.hetero: n

1,GLY,44
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 44
entity poly seq.hetero: n

1,ILE,45
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 45
entity poly seq.hetero: n

1,PHE,46
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 46
entity poly seq.hetero: n

1,VAL,47
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 47
entity poly seq.hetero: n

1,TYR,48
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 48
entity poly seq.hetero: n

1,MET,49
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 49
entity poly seq.hetero: n

1,VAL,50
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 50
entity poly seq.hetero: n

1,HIS,51
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 51
entity poly seq.hetero: n

1,ARG,52
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 52
entity poly seq.hetero: n

1,SER,53
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 53
entity poly seq.hetero: n

1,CYS,54
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 54
entity poly seq.hetero: n

1,GLY,55
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 55
entity poly seq.hetero: n

1,THR,56
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 56
entity poly seq.hetero: n

1,SER,57
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 57
entity poly seq.hetero: n

1,CYS,58
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 58
entity poly seq.hetero: n

1,PHE,59
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 59
entity poly seq.hetero: n

1,GLU,60
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 60
entity poly seq.hetero: n

1,LEU,61
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 61
entity poly seq.hetero: n

1,GLU,62
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 62
entity poly seq.hetero: n

1,LYS,63
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 63
entity poly seq.hetero: n

1,LEU,64
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 64
entity poly seq.hetero: n

1,CYS,65
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 65
entity poly seq.hetero: n

1,ARG,66
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 66
entity poly seq.hetero: n

1,PHE,67
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 67
entity poly seq.hetero: n

1,ILE,68
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 68
entity poly seq.hetero: n

1,MET,69
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 69
entity poly seq.hetero: n

1,SER,70
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 70
entity poly seq.hetero: n

1,VAL,71
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 71
entity poly seq.hetero: n

1,LYS,72
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 72
entity poly seq.hetero: n

1,LYS,73
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 73
entity poly seq.hetero: n

1,ASN,74
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 74
entity poly seq.hetero: n

1,TYR,75
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 75
entity poly seq.hetero: n

1,ARG,76
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 76
entity poly seq.hetero: n

1,ARG,77
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 77
entity poly seq.hetero: n

1,VAL,78
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 78
entity poly seq.hetero: n

1,PRO,79
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 79
entity poly seq.hetero: n

1,TYR,80
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 80
entity poly seq.hetero: n

1,HIS,81
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 81
entity poly seq.hetero: n

1,ASN,82
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 82
entity poly seq.hetero: n

1,TRP,83
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 83
entity poly seq.hetero: n

1,LYS,84
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 84
entity poly seq.hetero: n

1,HIS,85
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 85
entity poly seq.hetero: n

1,ALA,86
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 86
entity poly seq.hetero: n

1,VAL,87
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 87
entity poly seq.hetero: n

1,THR,88
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 88
entity poly seq.hetero: n

1,VAL,89
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 89
entity poly seq.hetero: n

1,ALA,90
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 90
entity poly seq.hetero: n

1,HIS,91
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 91
entity poly seq.hetero: n

1,CYS,92
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 92
entity poly seq.hetero: n

1,MET,93
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 93
entity poly seq.hetero: n

1,TYR,94
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 94
entity poly seq.hetero: n

1,ALA,95
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 95
entity poly seq.hetero: n

1,ILE,96
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 96
entity poly seq.hetero: n

1,LEU,97
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 97
entity poly seq.hetero: n

1,GLN,98
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 98
entity poly seq.hetero: n

1,ASN,99
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 99
entity poly seq.hetero: n

1,ASN,100
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 100
entity poly seq.hetero: n

1,HIS,101
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 101
entity poly seq.hetero: n

1,THR,102
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 102
entity poly seq.hetero: n

1,LEU,103
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 103
entity poly seq.hetero: n

1,PHE,104
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 104
entity poly seq.hetero: n

1,THR,105
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 105
entity poly seq.hetero: n

1,ASP,106
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 106
entity poly seq.hetero: n

1,LEU,107
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 107
entity poly seq.hetero: n

1,GLU,108
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 108
entity poly seq.hetero: n

1,ARG,109
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 109
entity poly seq.hetero: n

1,LYS,110
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 110
entity poly seq.hetero: n

1,GLY,111
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 111
entity poly seq.hetero: n

1,LEU,112
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 112
entity poly seq.hetero: n

1,LEU,113
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 113
entity poly seq.hetero: n

1,ILE,114
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 114
entity poly seq.hetero: n

1,ALA,115
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 115
entity poly seq.hetero: n

1,CYS,116
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 116
entity poly seq.hetero: n

1,LEU,117
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 117
entity poly seq.hetero: n

1,CYS,118
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 118
entity poly seq.hetero: n

1,HIS,119
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 119
entity poly seq.hetero: n

1,ASP,120
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 120
entity poly seq.hetero: n

1,LEU,121
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 121
entity poly seq.hetero: n

1,ASP,122
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 122
entity poly seq.hetero: n

1,HIS,123
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 123
entity poly seq.hetero: n

1,ARG,124
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 124
entity poly seq.hetero: n

1,GLY,125
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 125
entity poly seq.hetero: n

1,PHE,126
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 126
entity poly seq.hetero: n

1,SER,127
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 127
entity poly seq.hetero: n

1,ASN,128
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 128
entity poly seq.hetero: n

1,SER,129
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 129
entity poly seq.hetero: n

1,TYR,130
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 130
entity poly seq.hetero: n

1,LEU,131
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 131
entity poly seq.hetero: n

1,GLN,132
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 132
entity poly seq.hetero: n

1,LYS,133
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 133
entity poly seq.hetero: n

1,PHE,134
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 134
entity poly seq.hetero: n

1,ASP,135
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 135
entity poly seq.hetero: n

1,HIS,136
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 136
entity poly seq.hetero: n

1,PRO,137
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 137
entity poly seq.hetero: n

1,LEU,138
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 138
entity poly seq.hetero: n

1,ALA,139
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 139
entity poly seq.hetero: n

1,ALA,140
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 140
entity poly seq.hetero: n

1,LEU,141
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 141
entity poly seq.hetero: n

1,TYR,142
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 142
entity poly seq.hetero: n

1,SER,143
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 143
entity poly seq.hetero: n

1,THR,144
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 144
entity poly seq.hetero: n

1,SER,145
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 145
entity poly seq.hetero: n

1,THR,146
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 146
entity poly seq.hetero: n

1,MET,147
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 147
entity poly seq.hetero: n

1,GLU,148
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 148
entity poly seq.hetero: n

1,GLN,149
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 149
entity poly seq.hetero: n

1,HIS,150
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 150
entity poly seq.hetero: n

1,HIS,151
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 151
entity poly seq.hetero: n

1,PHE,152
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 152
entity poly seq.hetero: n

1,SER,153
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 153
entity poly seq.hetero: n

1,GLN,154
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 154
entity poly seq.hetero: n

1,THR,155
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 155
entity poly seq.hetero: n

1,VAL,156
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 156
entity poly seq.hetero: n

1,SER,157
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 157
entity poly seq.hetero: n

1,ILE,158
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 158
entity poly seq.hetero: n

1,LEU,159
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 159
entity poly seq.hetero: n

1,GLN,160
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 160
entity poly seq.hetero: n

1,LEU,161
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 161
entity poly seq.hetero: n

1,GLU,162
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 162
entity poly seq.hetero: n

1,GLY,163
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 163
entity poly seq.hetero: n

1,HIS,164
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 164
entity poly seq.hetero: n

1,ASN,165
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 165
entity poly seq.hetero: n

1,ILE,166
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 166
entity poly seq.hetero: n

1,PHE,167
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 167
entity poly seq.hetero: n

1,SER,168
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 168
entity poly seq.hetero: n

1,THR,169
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 169
entity poly seq.hetero: n

1,LEU,170
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 170
entity poly seq.hetero: n

1,SER,171
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 171
entity poly seq.hetero: n

1,SER,172
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 172
entity poly seq.hetero: n

1,SER,173
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 173
entity poly seq.hetero: n

1,GLU,174
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 174
entity poly seq.hetero: n

1,TYR,175
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 175
entity poly seq.hetero: n

1,GLU,176
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 176
entity poly seq.hetero: n

1,GLN,177
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 177
entity poly seq.hetero: n

1,VAL,178
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 178
entity poly seq.hetero: n

1,LEU,179
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 179
entity poly seq.hetero: n

1,GLU,180
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 180
entity poly seq.hetero: n

1,ILE,181
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 181
entity poly seq.hetero: n

1,ILE,182
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 182
entity poly seq.hetero: n

1,ARG,183
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 183
entity poly seq.hetero: n

1,LYS,184
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 184
entity poly seq.hetero: n

1,ALA,185
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 185
entity poly seq.hetero: n

1,ILE,186
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 186
entity poly seq.hetero: n

1,ILE,187
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 187
entity poly seq.hetero: n

1,ALA,188
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 188
entity poly seq.hetero: n

1,THR,189
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 189
entity poly seq.hetero: n

1,ASP,190
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 190
entity poly seq.hetero: n

1,LEU,191
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 191
entity poly seq.hetero: n

1,ALA,192
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 192
entity poly seq.hetero: n

1,LEU,193
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 193
entity poly seq.hetero: n

1,TYR,194
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 194
entity poly seq.hetero: n

1,PHE,195
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 195
entity poly seq.hetero: n

1,GLY,196
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 196
entity poly seq.hetero: n

1,ASN,197
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 197
entity poly seq.hetero: n

1,ARG,198
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 198
entity poly seq.hetero: n

1,LYS,199
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 199
entity poly seq.hetero: n

1,GLN,200
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 200
entity poly seq.hetero: n

1,LEU,201
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 201
entity poly seq.hetero: n

1,GLU,202
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 202
entity poly seq.hetero: n

1,GLU,203
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 203
entity poly seq.hetero: n

1,MET,204
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 204
entity poly seq.hetero: n

1,TYR,205
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 205
entity poly seq.hetero: n

1,GLN,206
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 206
entity poly seq.hetero: n

1,THR,207
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 207
entity poly seq.hetero: n

1,GLY,208
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 208
entity poly seq.hetero: n

1,SER,209
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 209
entity poly seq.hetero: n

1,LEU,210
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 210
entity poly seq.hetero: n

1,ASN,211
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 211
entity poly seq.hetero: n

1,LEU,212
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 212
entity poly seq.hetero: n

1,ASN,213
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 213
entity poly seq.hetero: n

1,ASN,214
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 214
entity poly seq.hetero: n

1,GLN,215
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 215
entity poly seq.hetero: n

1,SER,216
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 216
entity poly seq.hetero: n

1,HIS,217
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: HIS
entity poly seq.num: 217
entity poly seq.hetero: n

1,ARG,218
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 218
entity poly seq.hetero: n

1,ASP,219
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 219
entity poly seq.hetero: n

1,ARG,220
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 220
entity poly seq.hetero: n

1,VAL,221
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 221
entity poly seq.hetero: n

1,ILE,222
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 222
entity poly seq.hetero: n

1,GLY,223
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 223
entity poly seq.hetero: n

1,LEU,224
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 224
entity poly seq.hetero: n

1,MET,225
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 225
entity poly seq.hetero: n

1,MET,226
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 226
entity poly seq.hetero: n

1,THR,227
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 227
entity poly seq.hetero: n

1,ALA,228
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 228
entity poly seq.hetero: n

1,CYS,229
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 229
entity poly seq.hetero: n

1,ASP,230
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 230
entity poly seq.hetero: n

1,LEU,231
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 231
entity poly seq.hetero: n

1,CYS,232
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 232
entity poly seq.hetero: n

1,SER,233
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 233
entity poly seq.hetero: n

1,VAL,234
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 234
entity poly seq.hetero: n

1,THR,235
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 235
entity poly seq.hetero: n

1,LYS,236
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 236
entity poly seq.hetero: n

1,LEU,237
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 237
entity poly seq.hetero: n

1,TRP,238
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 238
entity poly seq.hetero: n

1,PRO,239
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 239
entity poly seq.hetero: n

1,VAL,240
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 240
entity poly seq.hetero: n

1,THR,241
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 241
entity poly seq.hetero: n

1,LYS,242
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 242
entity poly seq.hetero: n

1,LEU,243
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 243
entity poly seq.hetero: n

1,THR,244
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 244
entity poly seq.hetero: n

1,ALA,245
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 245
entity poly seq.hetero: n

1,ASN,246
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 246
entity poly seq.hetero: n

1,ASP,247
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 247
entity poly seq.hetero: n

1,ILE,248
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 248
entity poly seq.hetero: n

1,TYR,249
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 249
entity poly seq.hetero: n

1,ALA,250
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 250
entity poly seq.hetero: n

1,GLU,251
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 251
entity poly seq.hetero: n

1,PHE,252
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 252
entity poly seq.hetero: n

1,TRP,253
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 253
entity poly seq.hetero: n

1,ALA,254
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 254
entity poly seq.hetero: n

1,GLU,255
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 255
entity poly seq.hetero: n

1,GLY,256
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 256
entity poly seq.hetero: n

1,ASP,257
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 257
entity poly seq.hetero: n

1,GLU,258
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 258
entity poly seq.hetero: n

1,MET,259
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 259
entity poly seq.hetero: n

1,LYS,260
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 260
entity poly seq.hetero: n

1,LYS,261
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 261
entity poly seq.hetero: n

1,LEU,262
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 262
entity poly seq.hetero: n

1,GLY,263
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 263
entity poly seq.hetero: n

1,ILE,264
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 264
entity poly seq.hetero: n

1,GLN,265
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 265
entity poly seq.hetero: n

1,PRO,266
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 266
entity poly seq.hetero: n

1,ILE,267
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 267
entity poly seq.hetero: n

1,PRO,268
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 268
entity poly seq.hetero: n

1,MET,269
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 269
entity poly seq.hetero: n

1,MET,270
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: MET
entity poly seq.num: 270
entity poly seq.hetero: n

1,ASP,271
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 271
entity poly seq.hetero: n

1,ARG,272
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 272
entity poly seq.hetero: n

1,ASP,273
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 273
entity poly seq.hetero: n

1,LYS,274
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 274
entity poly seq.hetero: n

1,LYS,275
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 275
entity poly seq.hetero: n

1,ASP,276
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 276
entity poly seq.hetero: n

1,GLU,277
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 277
entity poly seq.hetero: n

1,VAL,278
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 278
entity poly seq.hetero: n

1,PRO,279
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 279
entity poly seq.hetero: n

1,GLN,280
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 280
entity poly seq.hetero: n

1,GLY,281
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 281
entity poly seq.hetero: n

1,GLN,282
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 282
entity poly seq.hetero: n

1,LEU,283
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 283
entity poly seq.hetero: n

1,GLY,284
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 284
entity poly seq.hetero: n

1,PHE,285
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PHE
entity poly seq.num: 285
entity poly seq.hetero: n

1,TYR,286
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 286
entity poly seq.hetero: n

1,ASN,287
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 287
entity poly seq.hetero: n

1,ALA,288
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 288
entity poly seq.hetero: n

1,VAL,289
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 289
entity poly seq.hetero: n

1,ALA,290
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 290
entity poly seq.hetero: n

1,ILE,291
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 291
entity poly seq.hetero: n

1,PRO,292
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 292
entity poly seq.hetero: n

1,CYS,293
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 293
entity poly seq.hetero: n

1,TYR,294
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TYR
entity poly seq.num: 294
entity poly seq.hetero: n

1,THR,295
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 295
entity poly seq.hetero: n

1,THR,296
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 296
entity poly seq.hetero: n

1,LEU,297
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 297
entity poly seq.hetero: n

1,THR,298
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 298
entity poly seq.hetero: n

1,GLN,299
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 299
entity poly seq.hetero: n

1,ILE,300
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 300
entity poly seq.hetero: n

1,LEU,301
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 301
entity poly seq.hetero: n

1,PRO,302
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 302
entity poly seq.hetero: n

1,PRO,303
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 303
entity poly seq.hetero: n

1,THR,304
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 304
entity poly seq.hetero: n

1,GLU,305
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 305
entity poly seq.hetero: n

1,PRO,306
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 306
entity poly seq.hetero: n

1,LEU,307
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 307
entity poly seq.hetero: n

1,LEU,308
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 308
entity poly seq.hetero: n

1,LYS,309
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 309
entity poly seq.hetero: n

1,ALA,310
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 310
entity poly seq.hetero: n

1,CYS,311
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: CYS
entity poly seq.num: 311
entity poly seq.hetero: n

1,ARG,312
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 312
entity poly seq.hetero: n

1,ASP,313
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASP
entity poly seq.num: 313
entity poly seq.hetero: n

1,ASN,314
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ASN
entity poly seq.num: 314
entity poly seq.hetero: n

1,LEU,315
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LEU
entity poly seq.num: 315
entity poly seq.hetero: n

1,SER,316
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 316
entity poly seq.hetero: n

1,GLN,317
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 317
entity poly seq.hetero: n

1,TRP,318
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 318
entity poly seq.hetero: n

1,GLU,319
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 319
entity poly seq.hetero: n

1,LYS,320
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 320
entity poly seq.hetero: n

1,VAL,321
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 321
entity poly seq.hetero: n

1,ILE,322
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 322
entity poly seq.hetero: n

1,ARG,323
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ARG
entity poly seq.num: 323
entity poly seq.hetero: n

1,GLY,324
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLY
entity poly seq.num: 324
entity poly seq.hetero: n

1,GLU,325
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 325
entity poly seq.hetero: n

1,GLU,326
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLU
entity poly seq.num: 326
entity poly seq.hetero: n

1,THR,327
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 327
entity poly seq.hetero: n

1,ALA,328
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 328
entity poly seq.hetero: n

1,THR,329
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: THR
entity poly seq.num: 329
entity poly seq.hetero: n

1,TRP,330
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: TRP
entity poly seq.num: 330
entity poly seq.hetero: n

1,ILE,331
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ILE
entity poly seq.num: 331
entity poly seq.hetero: n

1,SER,332
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 332
entity poly seq.hetero: n

1,SER,333
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 333
entity poly seq.hetero: n

1,PRO,334
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: PRO
entity poly seq.num: 334
entity poly seq.hetero: n

1,SER,335
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: SER
entity poly seq.num: 335
entity poly seq.hetero: n

1,VAL,336
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: VAL
entity poly seq.num: 336
entity poly seq.hetero: n

1,ALA,337
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 337
entity poly seq.hetero: n

1,GLN,338
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: GLN
entity poly seq.num: 338
entity poly seq.hetero: n

1,LYS,339
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: LYS
entity poly seq.num: 339
entity poly seq.hetero: n

1,ALA,340
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 340
entity poly seq.hetero: n

1,ALA,341
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 341
entity poly seq.hetero: n

1,ALA,342
type: entity poly seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: chem comp
reference to entity poly: entity poly
entity poly seq.entity id: 1
entity poly seq.mon id: ALA
entity poly seq.num: 342
entity poly seq.hetero: n

1,SER,343
type: entity poly seq
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pdbx nonpoly scheme.ndb seq num: 28
pdbx nonpoly scheme.auth mon id: HOH
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pdbx nonpoly scheme.pdb strand id: A

I,29
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 29
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1034
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pdbx nonpoly scheme.pdb strand id: A

I,30
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 30
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 13
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1030
pdbx nonpoly scheme.pdb strand id: A

I,31
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 31
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 20
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
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pdbx nonpoly scheme.pdb seq num: 1031
pdbx nonpoly scheme.pdb strand id: A

I,32
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 32
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1003
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1032
pdbx nonpoly scheme.pdb strand id: A

I,33
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 33
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1008
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1033
pdbx nonpoly scheme.pdb strand id: A

I,34
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 34
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1031
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1034
pdbx nonpoly scheme.pdb strand id: A

I,35
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 35
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1013
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1035
pdbx nonpoly scheme.pdb strand id: A

I,36
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 36
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1018
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1036
pdbx nonpoly scheme.pdb strand id: A

I,37
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 37
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1020
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1037
pdbx nonpoly scheme.pdb strand id: A

I,38
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 38
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1022
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1038
pdbx nonpoly scheme.pdb strand id: A

I,39
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 39
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 17
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1039
pdbx nonpoly scheme.pdb strand id: A

I,40
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 40
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 12
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1040
pdbx nonpoly scheme.pdb strand id: A

I,41
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 41
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1033
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1041
pdbx nonpoly scheme.pdb strand id: A

I,42
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 42
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1007
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1042
pdbx nonpoly scheme.pdb strand id: A

I,43
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 43
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 36
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1043
pdbx nonpoly scheme.pdb strand id: A

I,44
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 44
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1035
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1044
pdbx nonpoly scheme.pdb strand id: A

I,45
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 45
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 4
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1045
pdbx nonpoly scheme.pdb strand id: A

I,46
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 46
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1027
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1046
pdbx nonpoly scheme.pdb strand id: A

I,47
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 47
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 26
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1047
pdbx nonpoly scheme.pdb strand id: A

I,48
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 48
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1032
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1048
pdbx nonpoly scheme.pdb strand id: A

I,49
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 49
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1028
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1049
pdbx nonpoly scheme.pdb strand id: A

I,50
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 50
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1029
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1050
pdbx nonpoly scheme.pdb strand id: A

I,51
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 51
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 23
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1051
pdbx nonpoly scheme.pdb strand id: A

I,52
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 52
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 25
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1052
pdbx nonpoly scheme.pdb strand id: A

I,53
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 53
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1053
pdbx nonpoly scheme.pdb strand id: A

I,54
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 54
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1036
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1054
pdbx nonpoly scheme.pdb strand id: A

I,55
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 55
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 40
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1055
pdbx nonpoly scheme.pdb strand id: A

I,56
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: I
pdbx nonpoly scheme.ndb seq num: 56
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 1037
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 1056
pdbx nonpoly scheme.pdb strand id: A

J,1
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 1
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 908
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 901
pdbx nonpoly scheme.pdb strand id: B

J,2
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 2
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 32
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 902
pdbx nonpoly scheme.pdb strand id: B

J,3
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 3
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 37
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 903
pdbx nonpoly scheme.pdb strand id: B

J,4
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 4
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 901
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 904
pdbx nonpoly scheme.pdb strand id: B

J,5
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 5
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 30
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 905
pdbx nonpoly scheme.pdb strand id: B

J,6
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 6
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 21
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 906
pdbx nonpoly scheme.pdb strand id: B

J,7
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 7
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 29
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 907
pdbx nonpoly scheme.pdb strand id: B

J,8
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 8
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 14
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 908
pdbx nonpoly scheme.pdb strand id: B

J,9
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 9
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 912
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 909
pdbx nonpoly scheme.pdb strand id: B

J,10
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 10
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 907
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 910
pdbx nonpoly scheme.pdb strand id: B

J,11
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 11
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 3
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 911
pdbx nonpoly scheme.pdb strand id: B

J,12
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 12
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 2
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 912
pdbx nonpoly scheme.pdb strand id: B

J,13
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 13
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 919
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 913
pdbx nonpoly scheme.pdb strand id: B

J,14
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 14
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 910
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 914
pdbx nonpoly scheme.pdb strand id: B

J,15
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 15
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 42
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 915
pdbx nonpoly scheme.pdb strand id: B

J,16
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 16
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 28
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 916
pdbx nonpoly scheme.pdb strand id: B

J,17
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 17
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 920
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 917
pdbx nonpoly scheme.pdb strand id: B

J,18
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 18
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 915
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 918
pdbx nonpoly scheme.pdb strand id: B

J,19
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 19
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 6
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 919
pdbx nonpoly scheme.pdb strand id: B

J,20
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 20
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 909
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 920
pdbx nonpoly scheme.pdb strand id: B

J,21
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 21
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 918
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 921
pdbx nonpoly scheme.pdb strand id: B

J,22
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 22
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 913
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 922
pdbx nonpoly scheme.pdb strand id: B

J,23
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 23
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 923
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 923
pdbx nonpoly scheme.pdb strand id: B

J,24
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 24
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 903
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 924
pdbx nonpoly scheme.pdb strand id: B

J,25
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 25
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 16
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 925
pdbx nonpoly scheme.pdb strand id: B

J,26
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 26
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 911
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 926
pdbx nonpoly scheme.pdb strand id: B

J,27
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 27
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 914
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 927
pdbx nonpoly scheme.pdb strand id: B

J,28
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 28
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 35
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 928
pdbx nonpoly scheme.pdb strand id: B

J,29
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 29
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 31
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 929
pdbx nonpoly scheme.pdb strand id: B

J,30
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 30
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 905
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 930
pdbx nonpoly scheme.pdb strand id: B

J,31
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 31
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 41
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 931
pdbx nonpoly scheme.pdb strand id: B

J,32
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 32
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 43
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 932
pdbx nonpoly scheme.pdb strand id: B

J,33
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 33
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 902
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 933
pdbx nonpoly scheme.pdb strand id: B

J,34
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 34
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 8
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 934
pdbx nonpoly scheme.pdb strand id: B

J,35
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 35
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 924
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 935
pdbx nonpoly scheme.pdb strand id: B

J,36
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 36
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 10
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 936
pdbx nonpoly scheme.pdb strand id: B

J,37
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 37
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 44
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 937
pdbx nonpoly scheme.pdb strand id: B

J,38
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 38
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 9
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 938
pdbx nonpoly scheme.pdb strand id: B

J,39
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 39
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 916
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 939
pdbx nonpoly scheme.pdb strand id: B

J,40
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 40
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 15
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 940
pdbx nonpoly scheme.pdb strand id: B

J,41
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 41
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 904
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 941
pdbx nonpoly scheme.pdb strand id: B

J,42
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 42
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 922
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 942
pdbx nonpoly scheme.pdb strand id: B

J,43
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 43
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 917
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 943
pdbx nonpoly scheme.pdb strand id: B

J,44
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 44
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 19
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 944
pdbx nonpoly scheme.pdb strand id: B

J,45
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 45
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 921
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 945
pdbx nonpoly scheme.pdb strand id: B

J,46
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 46
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 18
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 946
pdbx nonpoly scheme.pdb strand id: B

J,47
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 47
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 27
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 947
pdbx nonpoly scheme.pdb strand id: B

J,48
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 48
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 925
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 948
pdbx nonpoly scheme.pdb strand id: B

J,49
type: pdbx nonpoly scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx nonpoly scheme.asym id: J
pdbx nonpoly scheme.ndb seq num: 49
pdbx nonpoly scheme.auth mon id: HOH
pdbx nonpoly scheme.auth seq num: 11
pdbx nonpoly scheme.entity id: 5
pdbx nonpoly scheme.mon id: HOH
pdbx nonpoly scheme.pdb mon id: HOH
pdbx nonpoly scheme.pdb seq num: 949
pdbx nonpoly scheme.pdb strand id: B

A,1,GLY,1
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 1
pdbx poly seq scheme.pdb seq num: 435
pdbx poly seq scheme.pdb strand id: A

A,1,SER,2
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 2
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 2
pdbx poly seq scheme.pdb seq num: 436
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,3
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 3
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 3
pdbx poly seq scheme.pdb seq num: 437
pdbx poly seq scheme.pdb strand id: A

A,1,MET,4
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 4
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 4
pdbx poly seq scheme.pdb seq num: 438
pdbx poly seq scheme.pdb strand id: A

A,1,SER,5
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 5
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 439
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 5
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 439
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,6
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 6
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 440
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 6
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 440
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,7
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 7
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 441
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 7
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 441
pdbx poly seq scheme.pdb strand id: A

A,1,THR,8
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 8
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 442
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 8
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 442
pdbx poly seq scheme.pdb strand id: A

A,1,SER,9
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 9
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 443
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 9
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 443
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,10
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 10
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 444
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 10
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 444
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,11
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 11
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 445
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 11
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 445
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,12
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 12
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 446
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 12
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 446
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,13
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 13
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 447
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 13
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 447
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,14
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 14
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 448
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 14
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 448
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,15
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 15
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 449
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 15
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 449
pdbx poly seq scheme.pdb strand id: A

A,1,MET,16
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 16
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 450
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 16
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 450
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,17
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 17
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 451
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 17
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 451
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,18
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 18
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 452
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 18
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 452
pdbx poly seq scheme.pdb strand id: A

A,1,THR,19
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 19
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 453
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 19
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 453
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,20
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 20
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 454
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 20
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 454
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,21
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 21
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 455
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 21
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 455
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,22
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 22
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 456
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 22
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 456
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,23
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 23
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 457
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 23
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 457
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,24
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 24
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 458
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 24
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 458
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,25
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 25
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 459
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 25
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 459
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,26
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 26
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 460
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 26
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 460
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,27
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 27
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 461
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 27
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 461
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,28
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 28
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 462
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 28
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 462
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,29
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 29
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 463
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 29
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 463
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,30
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 30
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 464
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 30
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 464
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,31
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 31
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 465
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 31
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 465
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,32
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 32
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 466
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 32
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 466
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,33
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 33
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 467
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 33
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 467
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,34
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 34
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 468
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 34
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 468
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,35
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 35
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 469
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 35
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 469
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,36
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 36
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 470
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 36
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 470
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,37
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 37
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 471
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 37
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 471
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,38
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 38
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 472
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 38
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 472
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,39
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 39
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 473
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 39
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 473
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,40
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 40
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 474
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 40
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 474
pdbx poly seq scheme.pdb strand id: A

A,1,MET,41
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 41
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 475
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 41
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 475
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,42
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 42
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 476
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 42
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 476
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,43
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 43
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 477
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 43
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 477
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,44
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 44
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 478
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 44
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 478
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,45
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 45
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 479
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 45
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 479
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,46
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 46
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 480
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 46
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 480
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,47
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 47
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 481
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 47
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 481
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,48
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 48
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 482
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 48
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 482
pdbx poly seq scheme.pdb strand id: A

A,1,MET,49
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 49
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 483
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 49
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 483
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,50
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 50
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 484
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 50
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 484
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,51
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 51
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 485
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 51
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 485
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,52
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 52
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 486
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 52
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 486
pdbx poly seq scheme.pdb strand id: A

A,1,SER,53
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 53
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 487
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 53
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 487
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,54
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 54
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 488
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 54
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 488
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,55
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 55
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 489
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 55
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 489
pdbx poly seq scheme.pdb strand id: A

A,1,THR,56
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 56
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 490
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 56
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 490
pdbx poly seq scheme.pdb strand id: A

A,1,SER,57
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 57
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 491
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 57
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 491
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,58
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 58
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 492
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 58
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 492
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,59
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 59
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 493
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 59
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 493
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,60
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 60
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 494
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 60
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 494
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,61
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 61
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 495
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 61
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 495
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,62
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 62
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 496
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 62
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 496
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,63
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 63
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 497
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 63
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 497
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,64
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 64
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 498
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 64
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 498
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,65
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 65
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 499
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 65
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 499
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,66
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 66
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 500
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 66
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 500
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,67
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 67
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 501
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 67
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 501
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,68
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 68
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 502
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 68
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 502
pdbx poly seq scheme.pdb strand id: A

A,1,MET,69
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 69
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 503
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 69
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 503
pdbx poly seq scheme.pdb strand id: A

A,1,SER,70
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 70
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 504
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 70
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 504
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,71
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 71
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 505
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 71
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 505
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,72
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 72
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 506
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 72
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 506
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,73
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 73
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 507
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 73
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 507
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,74
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 74
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 508
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 74
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 508
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,75
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 75
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 509
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 75
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 509
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,76
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 76
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 510
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 76
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 510
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,77
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 77
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 511
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 77
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 511
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,78
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 78
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 512
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 78
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 512
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,79
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 79
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 513
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 79
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 513
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,80
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 80
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 514
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 80
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 514
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,81
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 81
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 515
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 81
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 515
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,82
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 82
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 516
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 82
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 516
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,83
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 83
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 517
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 83
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 517
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,84
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 84
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 518
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 84
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 518
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,85
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 85
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 519
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 85
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 519
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,86
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 86
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 520
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 86
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 520
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,87
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 87
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 521
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 87
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 521
pdbx poly seq scheme.pdb strand id: A

A,1,THR,88
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 88
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 522
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 88
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 522
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,89
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 89
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 523
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 89
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 523
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,90
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 90
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 524
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 90
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 524
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,91
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 91
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 525
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 91
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 525
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,92
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 92
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 526
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 92
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 526
pdbx poly seq scheme.pdb strand id: A

A,1,MET,93
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 93
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 527
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 93
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 527
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,94
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 94
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 528
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 94
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 528
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,95
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 95
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 529
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 95
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 529
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,96
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 96
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 530
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 96
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 530
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,97
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 97
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 531
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 97
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 531
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,98
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 98
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 532
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 98
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 532
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,99
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 99
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 533
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 99
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 533
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,100
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 100
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 534
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 100
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 534
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,101
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 101
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 535
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 101
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 535
pdbx poly seq scheme.pdb strand id: A

A,1,THR,102
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 102
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 536
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 102
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 536
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,103
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 103
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 537
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 103
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 537
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,104
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 104
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 538
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 104
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 538
pdbx poly seq scheme.pdb strand id: A

A,1,THR,105
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 105
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 539
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 105
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 539
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,106
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 106
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 540
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 106
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 540
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,107
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 107
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 541
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 107
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 541
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,108
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 108
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 542
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 108
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 542
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,109
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 109
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 543
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 109
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 543
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,110
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 110
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 544
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 110
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 544
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,111
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 111
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 545
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 111
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 545
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,112
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 112
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 546
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 112
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 546
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,113
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 113
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 547
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 113
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 547
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,114
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 114
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 548
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 114
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 548
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,115
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 115
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 549
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 115
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 549
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,116
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 116
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 550
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 116
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 550
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,117
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 117
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 551
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 117
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 551
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,118
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 118
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 552
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 118
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 552
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,119
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 119
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 553
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 119
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 553
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,120
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 120
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 554
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 120
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 554
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,121
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 121
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 555
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 121
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 555
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,122
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 122
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 556
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 122
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 556
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,123
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 123
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 557
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 123
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 557
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,124
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 124
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 558
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 124
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 558
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,125
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 125
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 559
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 125
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 559
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,126
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 126
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 560
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 126
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 560
pdbx poly seq scheme.pdb strand id: A

A,1,SER,127
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 127
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 561
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 127
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 561
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,128
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 128
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 562
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 128
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 562
pdbx poly seq scheme.pdb strand id: A

A,1,SER,129
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 129
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 563
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 129
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 563
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,130
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 130
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 564
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 130
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 564
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,131
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 131
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 565
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 131
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 565
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,132
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 132
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 566
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 132
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 566
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,133
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 133
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 567
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 133
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 567
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,134
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 134
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 568
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 134
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 568
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,135
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 135
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 569
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 135
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 569
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,136
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 136
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 570
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 136
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 570
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,137
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 137
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 571
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 137
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 571
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,138
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 138
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 572
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 138
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 572
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,139
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 139
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 573
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 139
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 573
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,140
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 140
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 574
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 140
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 574
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,141
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 141
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 575
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 141
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 575
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,142
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 142
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 576
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 142
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 576
pdbx poly seq scheme.pdb strand id: A

A,1,SER,143
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 143
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 577
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 143
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 577
pdbx poly seq scheme.pdb strand id: A

A,1,THR,144
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 144
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 578
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 144
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 578
pdbx poly seq scheme.pdb strand id: A

A,1,SER,145
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 145
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 579
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 145
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 579
pdbx poly seq scheme.pdb strand id: A

A,1,THR,146
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 146
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 580
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 146
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 580
pdbx poly seq scheme.pdb strand id: A

A,1,MET,147
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 147
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 581
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 147
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 581
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,148
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 148
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 582
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 148
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 582
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,149
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 149
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 583
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 149
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 583
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,150
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 150
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 584
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 150
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 584
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,151
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 151
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 585
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 151
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 585
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,152
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 152
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 586
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 152
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 586
pdbx poly seq scheme.pdb strand id: A

A,1,SER,153
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 153
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 587
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 153
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 587
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,154
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 154
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 588
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 154
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 588
pdbx poly seq scheme.pdb strand id: A

A,1,THR,155
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 155
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 589
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 155
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 589
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,156
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 156
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 590
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 156
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 590
pdbx poly seq scheme.pdb strand id: A

A,1,SER,157
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 157
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 591
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 157
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 591
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,158
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 158
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 592
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 158
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 592
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,159
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 159
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 593
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 159
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 593
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,160
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 160
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 594
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 160
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 594
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,161
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 161
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 595
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 161
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 595
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,162
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 162
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 596
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 162
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 596
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,163
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 163
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 597
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 163
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 597
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,164
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 164
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 598
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 164
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 598
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,165
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 165
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 599
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 165
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 599
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,166
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 166
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 600
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 166
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 600
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,167
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 167
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 601
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 167
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 601
pdbx poly seq scheme.pdb strand id: A

A,1,SER,168
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 168
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 602
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 168
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 602
pdbx poly seq scheme.pdb strand id: A

A,1,THR,169
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 169
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 603
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 169
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 603
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,170
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 170
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 604
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 170
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 604
pdbx poly seq scheme.pdb strand id: A

A,1,SER,171
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 171
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 605
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 171
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 605
pdbx poly seq scheme.pdb strand id: A

A,1,SER,172
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 172
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 606
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 172
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 606
pdbx poly seq scheme.pdb strand id: A

A,1,SER,173
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 173
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 607
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 173
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 607
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,174
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 174
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 608
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 174
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 608
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,175
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 175
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 609
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 175
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 609
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,176
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 176
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 610
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 176
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 610
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,177
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 177
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 611
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 177
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 611
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,178
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 178
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 612
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 178
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 612
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,179
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 179
pdbx poly seq scheme.auth mon id: LEU
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pdbx poly seq scheme.hetero: n
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pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 613
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,180
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 180
pdbx poly seq scheme.auth mon id: GLU
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pdbx poly seq scheme.hetero: n
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pdbx poly seq scheme.pdb mon id: GLU
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pdbx poly seq scheme.pdb strand id: A

A,1,ILE,181
type: pdbx poly seq scheme
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reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 181
pdbx poly seq scheme.auth mon id: ILE
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pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 181
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 615
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,182
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 182
pdbx poly seq scheme.auth mon id: ILE
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pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 182
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 616
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,183
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 183
pdbx poly seq scheme.auth mon id: ARG
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pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 183
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 617
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,184
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 184
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 618
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 184
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 618
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,185
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 185
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 619
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 185
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 619
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,186
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 186
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 620
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 186
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 620
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,187
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 187
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 621
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 187
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 621
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,188
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 188
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 622
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 188
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 622
pdbx poly seq scheme.pdb strand id: A

A,1,THR,189
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 189
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 623
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 189
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 623
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,190
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 190
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 624
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 190
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 624
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,191
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 191
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 625
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 191
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 625
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,192
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 192
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 626
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 192
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 626
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,193
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 193
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 627
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 193
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 627
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,194
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 194
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 628
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 194
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 628
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,195
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 195
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 629
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 195
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 629
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,196
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 196
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 630
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 196
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 630
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,197
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 197
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 631
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 197
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 631
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,198
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 198
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 632
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 198
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 632
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,199
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 199
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 633
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 199
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 633
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,200
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 200
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 634
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 200
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 634
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,201
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 201
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 635
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 201
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 635
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,202
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 202
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 636
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 202
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 636
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,203
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 203
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 637
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 203
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 637
pdbx poly seq scheme.pdb strand id: A

A,1,MET,204
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 204
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 638
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 204
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 638
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,205
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 205
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 639
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 205
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 639
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,206
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 206
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 640
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 206
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 640
pdbx poly seq scheme.pdb strand id: A

A,1,THR,207
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 207
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 641
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 207
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 641
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,208
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 208
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 642
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 208
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 642
pdbx poly seq scheme.pdb strand id: A

A,1,SER,209
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 209
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 643
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 209
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 643
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,210
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 210
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 644
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 210
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 644
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,211
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 211
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 645
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 211
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 645
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,212
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 212
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 646
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 212
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 646
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,213
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 213
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 647
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 213
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 647
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,214
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 214
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 648
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 214
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 648
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,215
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 215
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 649
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 215
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 649
pdbx poly seq scheme.pdb strand id: A

A,1,SER,216
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 216
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 650
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 216
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 650
pdbx poly seq scheme.pdb strand id: A

A,1,HIS,217
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 217
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 651
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 217
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 651
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,218
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 218
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 652
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 218
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 652
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,219
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 219
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 653
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 219
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 653
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,220
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 220
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 654
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 220
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 654
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,221
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 221
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 655
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 221
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 655
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,222
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 222
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 656
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 222
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 656
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,223
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 223
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 657
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 223
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 657
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,224
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 224
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 658
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 224
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 658
pdbx poly seq scheme.pdb strand id: A

A,1,MET,225
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 225
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 659
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 225
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 659
pdbx poly seq scheme.pdb strand id: A

A,1,MET,226
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 226
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 660
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 226
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 660
pdbx poly seq scheme.pdb strand id: A

A,1,THR,227
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 227
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 661
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 227
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 661
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,228
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 228
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 662
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 228
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 662
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,229
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 229
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 663
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 229
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 663
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,230
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 230
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 664
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 230
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 664
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,231
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 231
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 665
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 231
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 665
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,232
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 232
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 666
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 232
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 666
pdbx poly seq scheme.pdb strand id: A

A,1,SER,233
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 233
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 667
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 233
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 667
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,234
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 234
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 668
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 234
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 668
pdbx poly seq scheme.pdb strand id: A

A,1,THR,235
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 235
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 669
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 235
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 669
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,236
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 236
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 670
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 236
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 670
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,237
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 237
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 671
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 237
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 671
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,238
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 238
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 672
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 238
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 672
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,239
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 239
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 673
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 239
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 673
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,240
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 240
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 674
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 240
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 674
pdbx poly seq scheme.pdb strand id: A

A,1,THR,241
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 241
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 675
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 241
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 675
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,242
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 242
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 676
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 242
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 676
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,243
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 243
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 677
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 243
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 677
pdbx poly seq scheme.pdb strand id: A

A,1,THR,244
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 244
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 678
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 244
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 678
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,245
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 245
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 679
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 245
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 679
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,246
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 246
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 680
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 246
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 680
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,247
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 247
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 681
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 247
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 681
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,248
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 248
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 682
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 248
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 682
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,249
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 249
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 683
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 249
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 683
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,250
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 250
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 684
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 250
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 684
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,251
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 251
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 685
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 251
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 685
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,252
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 252
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 686
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 252
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 686
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,253
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 253
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 687
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 253
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 687
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,254
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 254
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 688
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 254
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 688
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,255
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 255
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 689
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 255
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 689
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,256
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 256
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 690
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 256
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 690
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,257
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 257
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 691
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 257
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 691
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,258
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 258
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 692
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 258
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 692
pdbx poly seq scheme.pdb strand id: A

A,1,MET,259
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 259
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 693
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 259
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 693
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,260
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 260
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 694
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 260
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 694
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,261
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 261
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 695
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 261
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 695
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,262
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 262
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 696
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 262
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 696
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,263
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 263
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 697
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 263
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 697
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,264
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 264
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 698
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 264
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 698
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,265
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 265
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 699
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 265
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 699
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,266
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 266
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 700
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 266
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 700
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,267
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 267
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 701
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 267
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 701
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,268
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 268
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 702
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 268
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 702
pdbx poly seq scheme.pdb strand id: A

A,1,MET,269
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 269
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 703
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 269
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 703
pdbx poly seq scheme.pdb strand id: A

A,1,MET,270
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 270
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 704
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 270
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 704
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,271
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 271
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 705
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 271
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 705
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,272
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 272
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 706
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 272
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 706
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,273
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 273
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 707
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 273
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 707
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,274
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 274
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 708
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 274
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 708
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,275
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 275
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 709
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 275
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 709
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,276
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 276
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 710
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 276
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 710
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,277
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 277
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 711
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 277
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 711
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,278
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 278
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 712
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 278
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 712
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,279
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 279
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 713
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 279
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 713
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,280
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 280
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 714
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 280
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 714
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,281
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 281
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 715
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 281
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 715
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,282
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 282
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 716
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 282
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 716
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,283
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 283
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 717
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 283
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 717
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,284
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 284
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 718
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 284
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 718
pdbx poly seq scheme.pdb strand id: A

A,1,PHE,285
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 285
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 719
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 285
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 719
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,286
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 286
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 720
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 286
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 720
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,287
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 287
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 721
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 287
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 721
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,288
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 288
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 722
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 288
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 722
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,289
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 289
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 723
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 289
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 723
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,290
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 290
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 724
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 290
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 724
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,291
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 291
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 725
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 291
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 725
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,292
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 292
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 726
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 292
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 726
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,293
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 293
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 727
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 293
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 727
pdbx poly seq scheme.pdb strand id: A

A,1,TYR,294
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 294
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 728
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 294
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 728
pdbx poly seq scheme.pdb strand id: A

A,1,THR,295
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 295
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 729
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 295
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 729
pdbx poly seq scheme.pdb strand id: A

A,1,THR,296
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 296
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 730
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 296
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 730
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,297
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 297
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 731
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 297
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 731
pdbx poly seq scheme.pdb strand id: A

A,1,THR,298
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 298
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 732
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 298
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 732
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,299
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 299
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 733
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 299
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 733
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,300
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 300
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 734
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 300
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 734
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,301
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 301
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 735
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 301
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 735
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,302
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 302
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 736
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 302
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 736
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,303
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 303
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 737
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 303
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 737
pdbx poly seq scheme.pdb strand id: A

A,1,THR,304
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 304
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 738
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 304
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 738
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,305
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 305
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 739
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 305
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 739
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,306
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 306
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 740
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 306
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 740
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,307
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 307
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 741
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 307
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 741
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,308
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 308
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 742
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 308
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 742
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,309
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 309
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 743
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 309
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 743
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,310
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 310
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 744
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 310
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 744
pdbx poly seq scheme.pdb strand id: A

A,1,CYS,311
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 311
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 745
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 311
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 745
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,312
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 312
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 746
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 312
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 746
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,313
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 313
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 747
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 313
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 747
pdbx poly seq scheme.pdb strand id: A

A,1,ASN,314
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 314
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 748
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 314
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 748
pdbx poly seq scheme.pdb strand id: A

A,1,LEU,315
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 315
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 749
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 315
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 749
pdbx poly seq scheme.pdb strand id: A

A,1,SER,316
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 316
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 750
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 316
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 750
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,317
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 317
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 751
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 317
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 751
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,318
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 318
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 752
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 318
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 752
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,319
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 319
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 753
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 319
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 753
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,320
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 320
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 754
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 320
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 754
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,321
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 321
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 755
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 321
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 755
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,322
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 322
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 756
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 322
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 756
pdbx poly seq scheme.pdb strand id: A

A,1,ARG,323
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 323
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 757
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 323
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 757
pdbx poly seq scheme.pdb strand id: A

A,1,GLY,324
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 324
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 758
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 324
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 758
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,325
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 325
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 325
pdbx poly seq scheme.pdb seq num: 759
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,326
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 326
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 326
pdbx poly seq scheme.pdb seq num: 760
pdbx poly seq scheme.pdb strand id: A

A,1,THR,327
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 327
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 327
pdbx poly seq scheme.pdb seq num: 761
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,328
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 328
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 328
pdbx poly seq scheme.pdb seq num: 762
pdbx poly seq scheme.pdb strand id: A

A,1,THR,329
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 329
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 329
pdbx poly seq scheme.pdb seq num: 763
pdbx poly seq scheme.pdb strand id: A

A,1,TRP,330
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 330
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 330
pdbx poly seq scheme.pdb seq num: 764
pdbx poly seq scheme.pdb strand id: A

A,1,ILE,331
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 331
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 331
pdbx poly seq scheme.pdb seq num: 765
pdbx poly seq scheme.pdb strand id: A

A,1,SER,332
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 332
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 332
pdbx poly seq scheme.pdb seq num: 766
pdbx poly seq scheme.pdb strand id: A

A,1,SER,333
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 333
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 333
pdbx poly seq scheme.pdb seq num: 767
pdbx poly seq scheme.pdb strand id: A

A,1,PRO,334
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 334
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 334
pdbx poly seq scheme.pdb seq num: 768
pdbx poly seq scheme.pdb strand id: A

A,1,SER,335
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 335
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 335
pdbx poly seq scheme.pdb seq num: 769
pdbx poly seq scheme.pdb strand id: A

A,1,VAL,336
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 336
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 336
pdbx poly seq scheme.pdb seq num: 770
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,337
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 337
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 337
pdbx poly seq scheme.pdb seq num: 771
pdbx poly seq scheme.pdb strand id: A

A,1,GLN,338
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 338
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 338
pdbx poly seq scheme.pdb seq num: 772
pdbx poly seq scheme.pdb strand id: A

A,1,LYS,339
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 339
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 339
pdbx poly seq scheme.pdb seq num: 773
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,340
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 340
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 340
pdbx poly seq scheme.pdb seq num: 774
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,341
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 341
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 341
pdbx poly seq scheme.pdb seq num: 775
pdbx poly seq scheme.pdb strand id: A

A,1,ALA,342
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 342
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 342
pdbx poly seq scheme.pdb seq num: 776
pdbx poly seq scheme.pdb strand id: A

A,1,SER,343
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 343
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 343
pdbx poly seq scheme.pdb seq num: 777
pdbx poly seq scheme.pdb strand id: A

A,1,GLU,344
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 344
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 344
pdbx poly seq scheme.pdb seq num: 778
pdbx poly seq scheme.pdb strand id: A

A,1,ASP,345
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: A
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 345
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 345
pdbx poly seq scheme.pdb seq num: 779
pdbx poly seq scheme.pdb strand id: A

B,1,GLY,1
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 1
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 1
pdbx poly seq scheme.pdb seq num: 435
pdbx poly seq scheme.pdb strand id: B

B,1,SER,2
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 2
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 2
pdbx poly seq scheme.pdb seq num: 436
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,3
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 3
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 437
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 3
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 437
pdbx poly seq scheme.pdb strand id: B

B,1,MET,4
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 4
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 438
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 4
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 438
pdbx poly seq scheme.pdb strand id: B

B,1,SER,5
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 5
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 439
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 5
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 439
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,6
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 6
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 440
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 6
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 440
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,7
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 7
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 441
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 7
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 441
pdbx poly seq scheme.pdb strand id: B

B,1,THR,8
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 8
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 442
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 8
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 442
pdbx poly seq scheme.pdb strand id: B

B,1,SER,9
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 9
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 443
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 9
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 443
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,10
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 10
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 444
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 10
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 444
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,11
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 11
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 445
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 11
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 445
pdbx poly seq scheme.pdb strand id: B

B,1,TRP,12
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 12
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 446
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 12
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 446
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,13
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 13
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 447
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 13
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 447
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,14
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 14
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 448
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 14
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 448
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,15
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 15
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 449
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 15
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 449
pdbx poly seq scheme.pdb strand id: B

B,1,MET,16
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 16
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 450
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 16
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 450
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,17
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 17
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 451
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 17
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 451
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,18
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 18
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 452
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 18
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 452
pdbx poly seq scheme.pdb strand id: B

B,1,THR,19
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 19
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 453
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 19
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 453
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,20
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 20
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 454
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 20
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 454
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,21
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 21
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 455
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 21
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 455
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,22
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 22
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 456
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 22
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 456
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,23
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 23
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 457
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 23
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 457
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,24
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 24
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 458
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 24
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 458
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,25
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 25
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 459
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 25
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 459
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,26
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 26
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 460
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 26
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 460
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,27
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 27
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 461
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 27
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 461
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,28
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 28
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 462
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 28
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 462
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,29
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 29
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 463
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 29
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 463
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,30
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 30
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 464
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 30
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 464
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,31
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 31
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 465
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 31
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 465
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,32
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 32
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 466
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 32
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 466
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,33
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 33
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 467
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 33
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 467
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,34
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 34
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 468
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 34
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 468
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,35
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 35
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 469
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 35
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 469
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,36
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 36
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 470
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 36
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 470
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,37
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 37
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 471
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 37
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 471
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,38
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 38
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 472
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 38
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 472
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,39
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 39
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 473
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 39
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 473
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,40
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 40
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 474
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 40
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 474
pdbx poly seq scheme.pdb strand id: B

B,1,MET,41
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 41
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 475
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 41
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 475
pdbx poly seq scheme.pdb strand id: B

B,1,TRP,42
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 42
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 476
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 42
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 476
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,43
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 43
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 477
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 43
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 477
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,44
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 44
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 478
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 44
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 478
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,45
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 45
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 479
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 45
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 479
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,46
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 46
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 480
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 46
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 480
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,47
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 47
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 481
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 47
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 481
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,48
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 48
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 482
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 48
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 482
pdbx poly seq scheme.pdb strand id: B

B,1,MET,49
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 49
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 483
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 49
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 483
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,50
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 50
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 484
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 50
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 484
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,51
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 51
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 485
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 51
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 485
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,52
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 52
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 486
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 52
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 486
pdbx poly seq scheme.pdb strand id: B

B,1,SER,53
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 53
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 487
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 53
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 487
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,54
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 54
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 488
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 54
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 488
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,55
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 55
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 489
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 55
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 489
pdbx poly seq scheme.pdb strand id: B

B,1,THR,56
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 56
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 490
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 56
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 490
pdbx poly seq scheme.pdb strand id: B

B,1,SER,57
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 57
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 491
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 57
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 491
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,58
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 58
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 492
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 58
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 492
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,59
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 59
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 493
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 59
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 493
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,60
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 60
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 494
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 60
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 494
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,61
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 61
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 495
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 61
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 495
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,62
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 62
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 496
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 62
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 496
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,63
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 63
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 497
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 63
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 497
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,64
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 64
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 498
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 64
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 498
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,65
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 65
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 499
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 65
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 499
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,66
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 66
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 500
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 66
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 500
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,67
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 67
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 501
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 67
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 501
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,68
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 68
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 502
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 68
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 502
pdbx poly seq scheme.pdb strand id: B

B,1,MET,69
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 69
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 503
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 69
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 503
pdbx poly seq scheme.pdb strand id: B

B,1,SER,70
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 70
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 504
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 70
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 504
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,71
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 71
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 505
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 71
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 505
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,72
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 72
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 506
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 72
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 506
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,73
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 73
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 507
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 73
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 507
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,74
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 74
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 508
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 74
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 508
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,75
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 75
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 509
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 75
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 509
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,76
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 76
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 510
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 76
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 510
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,77
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 77
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 511
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 77
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 511
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,78
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 78
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 512
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 78
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 512
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,79
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 79
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 513
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 79
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 513
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,80
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 80
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 514
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 80
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 514
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,81
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 81
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 515
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 81
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 515
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,82
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 82
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 516
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 82
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 516
pdbx poly seq scheme.pdb strand id: B

B,1,TRP,83
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 83
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 517
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 83
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 517
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,84
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 84
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 518
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 84
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 518
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,85
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 85
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 519
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 85
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 519
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,86
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 86
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 520
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 86
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 520
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,87
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 87
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 521
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 87
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 521
pdbx poly seq scheme.pdb strand id: B

B,1,THR,88
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 88
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 522
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 88
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 522
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,89
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 89
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 523
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 89
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 523
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,90
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 90
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 524
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 90
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 524
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,91
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 91
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 525
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 91
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 525
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,92
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 92
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 526
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 92
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 526
pdbx poly seq scheme.pdb strand id: B

B,1,MET,93
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 93
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 527
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 93
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 527
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,94
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 94
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 528
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 94
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 528
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,95
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 95
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 529
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 95
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 529
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,96
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 96
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 530
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 96
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 530
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,97
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 97
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 531
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 97
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 531
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,98
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 98
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 532
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 98
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 532
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,99
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 99
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 533
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 99
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 533
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,100
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 100
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 534
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 100
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 534
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,101
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 101
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 535
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 101
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 535
pdbx poly seq scheme.pdb strand id: B

B,1,THR,102
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 102
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 536
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 102
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 536
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,103
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 103
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 537
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 103
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 537
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,104
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 104
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 538
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 104
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 538
pdbx poly seq scheme.pdb strand id: B

B,1,THR,105
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 105
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 539
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 105
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 539
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,106
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 106
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 540
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 106
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 540
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,107
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 107
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 541
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 107
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 541
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,108
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 108
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 542
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 108
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 542
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,109
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 109
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 543
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 109
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 543
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,110
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 110
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 544
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 110
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 544
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,111
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 111
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 545
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 111
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 545
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,112
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 112
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 546
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 112
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 546
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,113
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 113
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 547
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 113
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 547
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,114
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 114
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 548
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 114
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 548
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,115
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 115
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 549
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 115
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 549
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,116
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 116
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 550
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 116
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 550
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,117
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 117
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 551
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 117
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 551
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,118
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 118
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 552
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 118
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 552
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,119
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 119
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 553
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 119
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 553
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,120
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 120
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 554
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 120
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 554
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,121
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 121
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 555
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 121
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 555
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,122
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 122
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 556
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 122
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 556
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,123
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 123
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 557
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 123
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 557
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,124
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 124
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 558
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 124
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 558
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,125
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 125
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 559
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 125
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 559
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,126
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 126
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 560
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 126
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 560
pdbx poly seq scheme.pdb strand id: B

B,1,SER,127
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 127
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 561
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 127
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 561
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,128
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 128
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 562
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 128
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 562
pdbx poly seq scheme.pdb strand id: B

B,1,SER,129
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 129
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 563
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 129
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 563
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,130
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 130
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 564
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 130
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 564
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,131
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 131
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 565
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 131
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 565
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,132
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 132
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 566
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 132
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 566
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,133
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 133
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 567
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 133
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 567
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,134
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 134
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 568
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 134
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 568
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,135
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 135
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 569
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 135
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 569
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,136
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 136
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 570
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 136
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 570
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,137
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 137
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 571
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 137
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 571
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,138
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 138
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 572
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 138
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 572
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,139
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 139
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 573
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 139
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 573
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,140
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 140
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 574
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 140
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 574
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,141
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 141
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 575
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 141
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 575
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,142
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 142
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 576
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 142
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 576
pdbx poly seq scheme.pdb strand id: B

B,1,SER,143
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 143
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 577
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 143
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 577
pdbx poly seq scheme.pdb strand id: B

B,1,THR,144
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 144
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 578
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 144
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 578
pdbx poly seq scheme.pdb strand id: B

B,1,SER,145
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 145
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 579
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 145
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 579
pdbx poly seq scheme.pdb strand id: B

B,1,THR,146
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 146
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 580
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 146
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 580
pdbx poly seq scheme.pdb strand id: B

B,1,MET,147
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 147
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 581
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 147
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 581
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,148
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 148
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 582
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 148
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 582
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,149
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 149
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 583
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 149
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 583
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,150
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 150
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 584
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 150
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 584
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,151
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 151
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 585
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 151
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 585
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,152
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 152
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 586
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 152
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 586
pdbx poly seq scheme.pdb strand id: B

B,1,SER,153
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 153
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 587
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 153
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 587
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,154
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 154
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 588
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 154
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 588
pdbx poly seq scheme.pdb strand id: B

B,1,THR,155
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 155
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 589
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 155
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 589
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,156
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 156
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 590
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 156
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 590
pdbx poly seq scheme.pdb strand id: B

B,1,SER,157
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 157
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 591
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 157
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 591
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,158
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 158
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 592
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 158
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 592
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,159
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 159
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 593
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 159
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 593
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,160
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 160
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 594
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 160
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 594
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,161
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 161
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 595
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 161
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 595
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,162
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 162
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 596
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 162
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 596
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,163
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 163
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 597
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 163
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 597
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,164
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 164
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 598
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 164
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 598
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,165
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 165
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 599
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 165
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 599
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,166
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 166
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 600
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 166
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 600
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,167
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 167
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 601
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 167
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 601
pdbx poly seq scheme.pdb strand id: B

B,1,SER,168
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 168
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 602
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 168
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 602
pdbx poly seq scheme.pdb strand id: B

B,1,THR,169
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 169
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 603
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 169
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 603
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,170
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 170
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 604
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 170
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 604
pdbx poly seq scheme.pdb strand id: B

B,1,SER,171
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 171
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 605
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 171
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 605
pdbx poly seq scheme.pdb strand id: B

B,1,SER,172
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 172
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 606
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 172
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 606
pdbx poly seq scheme.pdb strand id: B

B,1,SER,173
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 173
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 607
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 173
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 607
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,174
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 174
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 608
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 174
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 608
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,175
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 175
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 609
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 175
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 609
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,176
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 176
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 610
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 176
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 610
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,177
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 177
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 611
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 177
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 611
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,178
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 178
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 612
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 178
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 612
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,179
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 179
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 613
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 179
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 613
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,180
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 180
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 614
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 180
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 614
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,181
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 181
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 615
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 181
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 615
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,182
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 182
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 616
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 182
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 616
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,183
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 183
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 617
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 183
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 617
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,184
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 184
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 618
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 184
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 618
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,185
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 185
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 619
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 185
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 619
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,186
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 186
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 620
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 186
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 620
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,187
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 187
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 621
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 187
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 621
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,188
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 188
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 622
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 188
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 622
pdbx poly seq scheme.pdb strand id: B

B,1,THR,189
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 189
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 623
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 189
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 623
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,190
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 190
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 624
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 190
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 624
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,191
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 191
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 625
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 191
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 625
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,192
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 192
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 626
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 192
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 626
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,193
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 193
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 627
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 193
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 627
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,194
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 194
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 628
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 194
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 628
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,195
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 195
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 629
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 195
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 629
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,196
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 196
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 630
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 196
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 630
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,197
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 197
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 631
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 197
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 631
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,198
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 198
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 632
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 198
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 632
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,199
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 199
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 633
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 199
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 633
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,200
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 200
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 634
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 200
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 634
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,201
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 201
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 635
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 201
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 635
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,202
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 202
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 636
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 202
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 636
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,203
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 203
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 637
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 203
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 637
pdbx poly seq scheme.pdb strand id: B

B,1,MET,204
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 204
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 638
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 204
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 638
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,205
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 205
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 639
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 205
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 639
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,206
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 206
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 640
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 206
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 640
pdbx poly seq scheme.pdb strand id: B

B,1,THR,207
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 207
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 641
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 207
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 641
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,208
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 208
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 642
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 208
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 642
pdbx poly seq scheme.pdb strand id: B

B,1,SER,209
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 209
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 643
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 209
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 643
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,210
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 210
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 644
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 210
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 644
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,211
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 211
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 645
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 211
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 645
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,212
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 212
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 646
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 212
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 646
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,213
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 213
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 647
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 213
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 647
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,214
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 214
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 648
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 214
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 648
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,215
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 215
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 649
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 215
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 649
pdbx poly seq scheme.pdb strand id: B

B,1,SER,216
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 216
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 650
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 216
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 650
pdbx poly seq scheme.pdb strand id: B

B,1,HIS,217
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: HIS
pdbx poly seq scheme.seq id: 217
pdbx poly seq scheme.auth mon id: HIS
pdbx poly seq scheme.auth seq num: 651
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 217
pdbx poly seq scheme.pdb mon id: HIS
pdbx poly seq scheme.pdb seq num: 651
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,218
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 218
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 652
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 218
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 652
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,219
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 219
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 653
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 219
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 653
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,220
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 220
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 654
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 220
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 654
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,221
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 221
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 655
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 221
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 655
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,222
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 222
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 656
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 222
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 656
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,223
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 223
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 657
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 223
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 657
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,224
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 224
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 658
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 224
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 658
pdbx poly seq scheme.pdb strand id: B

B,1,MET,225
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 225
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 659
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 225
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 659
pdbx poly seq scheme.pdb strand id: B

B,1,MET,226
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 226
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 660
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 226
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 660
pdbx poly seq scheme.pdb strand id: B

B,1,THR,227
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 227
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 661
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 227
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 661
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,228
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 228
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 662
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 228
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 662
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,229
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 229
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 663
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 229
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 663
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,230
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 230
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 664
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 230
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 664
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,231
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 231
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 665
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 231
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 665
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,232
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 232
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 666
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 232
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 666
pdbx poly seq scheme.pdb strand id: B

B,1,SER,233
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 233
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 667
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 233
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 667
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,234
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 234
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 668
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 234
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 668
pdbx poly seq scheme.pdb strand id: B

B,1,THR,235
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 235
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 669
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 235
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 669
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,236
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 236
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 670
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 236
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 670
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,237
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 237
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 671
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 237
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 671
pdbx poly seq scheme.pdb strand id: B

B,1,TRP,238
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 238
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 672
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 238
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 672
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,239
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 239
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 673
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 239
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 673
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,240
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 240
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 674
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 240
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 674
pdbx poly seq scheme.pdb strand id: B

B,1,THR,241
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 241
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 675
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 241
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 675
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,242
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 242
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 676
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 242
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 676
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,243
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 243
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 677
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 243
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 677
pdbx poly seq scheme.pdb strand id: B

B,1,THR,244
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 244
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 678
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 244
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 678
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,245
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 245
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 679
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 245
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 679
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,246
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 246
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 680
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 246
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 680
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,247
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 247
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 681
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 247
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 681
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,248
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 248
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 682
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 248
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 682
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,249
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 249
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 683
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 249
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 683
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,250
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 250
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 684
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 250
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 684
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,251
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 251
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 685
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 251
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 685
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,252
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 252
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 686
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 252
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 686
pdbx poly seq scheme.pdb strand id: B

B,1,TRP,253
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 253
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 687
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 253
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 687
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,254
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 254
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 688
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 254
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 688
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,255
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 255
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 689
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 255
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 689
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,256
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 256
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 690
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 256
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 690
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,257
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 257
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 691
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 257
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 691
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,258
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 258
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 692
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 258
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 692
pdbx poly seq scheme.pdb strand id: B

B,1,MET,259
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 259
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 693
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 259
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 693
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,260
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 260
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 694
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 260
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 694
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,261
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 261
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 695
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 261
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 695
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,262
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 262
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 696
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 262
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 696
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,263
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 263
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 697
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 263
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 697
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,264
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 264
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 698
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 264
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 698
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,265
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 265
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 699
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 265
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 699
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,266
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 266
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 700
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 266
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 700
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,267
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 267
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 701
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 267
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 701
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,268
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 268
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 702
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 268
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 702
pdbx poly seq scheme.pdb strand id: B

B,1,MET,269
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 269
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 703
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 269
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 703
pdbx poly seq scheme.pdb strand id: B

B,1,MET,270
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: MET
pdbx poly seq scheme.seq id: 270
pdbx poly seq scheme.auth mon id: MET
pdbx poly seq scheme.auth seq num: 704
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 270
pdbx poly seq scheme.pdb mon id: MET
pdbx poly seq scheme.pdb seq num: 704
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,271
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 271
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 705
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 271
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 705
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,272
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 272
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 706
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 272
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 706
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,273
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 273
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 707
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 273
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 707
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,274
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 274
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 708
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 274
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 708
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,275
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 275
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 709
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 275
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 709
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,276
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 276
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 710
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 276
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 710
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,277
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 277
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 711
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 277
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 711
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,278
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 278
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 712
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 278
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 712
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,279
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 279
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 713
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 279
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 713
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,280
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 280
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 714
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 280
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 714
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,281
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 281
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 715
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 281
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 715
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,282
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 282
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 716
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 282
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 716
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,283
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 283
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 717
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 283
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 717
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,284
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 284
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 718
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 284
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 718
pdbx poly seq scheme.pdb strand id: B

B,1,PHE,285
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PHE
pdbx poly seq scheme.seq id: 285
pdbx poly seq scheme.auth mon id: PHE
pdbx poly seq scheme.auth seq num: 719
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 285
pdbx poly seq scheme.pdb mon id: PHE
pdbx poly seq scheme.pdb seq num: 719
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,286
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 286
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 720
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 286
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 720
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,287
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 287
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 721
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 287
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 721
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,288
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 288
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 722
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 288
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 722
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,289
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 289
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 723
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 289
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 723
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,290
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 290
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 724
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 290
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 724
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,291
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 291
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 725
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 291
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 725
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,292
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 292
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 726
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 292
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 726
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,293
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 293
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 727
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 293
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 727
pdbx poly seq scheme.pdb strand id: B

B,1,TYR,294
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TYR
pdbx poly seq scheme.seq id: 294
pdbx poly seq scheme.auth mon id: TYR
pdbx poly seq scheme.auth seq num: 728
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 294
pdbx poly seq scheme.pdb mon id: TYR
pdbx poly seq scheme.pdb seq num: 728
pdbx poly seq scheme.pdb strand id: B

B,1,THR,295
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 295
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 729
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 295
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 729
pdbx poly seq scheme.pdb strand id: B

B,1,THR,296
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 296
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 730
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 296
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 730
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,297
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 297
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 731
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 297
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 731
pdbx poly seq scheme.pdb strand id: B

B,1,THR,298
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 298
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 732
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 298
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 732
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,299
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 299
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 733
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 299
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 733
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,300
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 300
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 734
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 300
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 734
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,301
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 301
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 735
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 301
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 735
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,302
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 302
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 736
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 302
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 736
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,303
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 303
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 737
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 303
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 737
pdbx poly seq scheme.pdb strand id: B

B,1,THR,304
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 304
pdbx poly seq scheme.auth mon id: THR
pdbx poly seq scheme.auth seq num: 738
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 304
pdbx poly seq scheme.pdb mon id: THR
pdbx poly seq scheme.pdb seq num: 738
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,305
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 305
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 739
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 305
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 739
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,306
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 306
pdbx poly seq scheme.auth mon id: PRO
pdbx poly seq scheme.auth seq num: 740
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 306
pdbx poly seq scheme.pdb mon id: PRO
pdbx poly seq scheme.pdb seq num: 740
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,307
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 307
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 741
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 307
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 741
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,308
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 308
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 742
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 308
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 742
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,309
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 309
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 743
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 309
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 743
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,310
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 310
pdbx poly seq scheme.auth mon id: ALA
pdbx poly seq scheme.auth seq num: 744
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 310
pdbx poly seq scheme.pdb mon id: ALA
pdbx poly seq scheme.pdb seq num: 744
pdbx poly seq scheme.pdb strand id: B

B,1,CYS,311
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: CYS
pdbx poly seq scheme.seq id: 311
pdbx poly seq scheme.auth mon id: CYS
pdbx poly seq scheme.auth seq num: 745
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 311
pdbx poly seq scheme.pdb mon id: CYS
pdbx poly seq scheme.pdb seq num: 745
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,312
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 312
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 746
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 312
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 746
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,313
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 313
pdbx poly seq scheme.auth mon id: ASP
pdbx poly seq scheme.auth seq num: 747
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 313
pdbx poly seq scheme.pdb mon id: ASP
pdbx poly seq scheme.pdb seq num: 747
pdbx poly seq scheme.pdb strand id: B

B,1,ASN,314
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASN
pdbx poly seq scheme.seq id: 314
pdbx poly seq scheme.auth mon id: ASN
pdbx poly seq scheme.auth seq num: 748
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 314
pdbx poly seq scheme.pdb mon id: ASN
pdbx poly seq scheme.pdb seq num: 748
pdbx poly seq scheme.pdb strand id: B

B,1,LEU,315
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LEU
pdbx poly seq scheme.seq id: 315
pdbx poly seq scheme.auth mon id: LEU
pdbx poly seq scheme.auth seq num: 749
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 315
pdbx poly seq scheme.pdb mon id: LEU
pdbx poly seq scheme.pdb seq num: 749
pdbx poly seq scheme.pdb strand id: B

B,1,SER,316
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 316
pdbx poly seq scheme.auth mon id: SER
pdbx poly seq scheme.auth seq num: 750
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 316
pdbx poly seq scheme.pdb mon id: SER
pdbx poly seq scheme.pdb seq num: 750
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,317
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 317
pdbx poly seq scheme.auth mon id: GLN
pdbx poly seq scheme.auth seq num: 751
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 317
pdbx poly seq scheme.pdb mon id: GLN
pdbx poly seq scheme.pdb seq num: 751
pdbx poly seq scheme.pdb strand id: B

B,1,TRP,318
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 318
pdbx poly seq scheme.auth mon id: TRP
pdbx poly seq scheme.auth seq num: 752
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 318
pdbx poly seq scheme.pdb mon id: TRP
pdbx poly seq scheme.pdb seq num: 752
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,319
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 319
pdbx poly seq scheme.auth mon id: GLU
pdbx poly seq scheme.auth seq num: 753
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 319
pdbx poly seq scheme.pdb mon id: GLU
pdbx poly seq scheme.pdb seq num: 753
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,320
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 320
pdbx poly seq scheme.auth mon id: LYS
pdbx poly seq scheme.auth seq num: 754
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 320
pdbx poly seq scheme.pdb mon id: LYS
pdbx poly seq scheme.pdb seq num: 754
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,321
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 321
pdbx poly seq scheme.auth mon id: VAL
pdbx poly seq scheme.auth seq num: 755
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 321
pdbx poly seq scheme.pdb mon id: VAL
pdbx poly seq scheme.pdb seq num: 755
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,322
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 322
pdbx poly seq scheme.auth mon id: ILE
pdbx poly seq scheme.auth seq num: 756
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 322
pdbx poly seq scheme.pdb mon id: ILE
pdbx poly seq scheme.pdb seq num: 756
pdbx poly seq scheme.pdb strand id: B

B,1,ARG,323
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ARG
pdbx poly seq scheme.seq id: 323
pdbx poly seq scheme.auth mon id: ARG
pdbx poly seq scheme.auth seq num: 757
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 323
pdbx poly seq scheme.pdb mon id: ARG
pdbx poly seq scheme.pdb seq num: 757
pdbx poly seq scheme.pdb strand id: B

B,1,GLY,324
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLY
pdbx poly seq scheme.seq id: 324
pdbx poly seq scheme.auth mon id: GLY
pdbx poly seq scheme.auth seq num: 758
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 324
pdbx poly seq scheme.pdb mon id: GLY
pdbx poly seq scheme.pdb seq num: 758
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,325
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 325
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 325
pdbx poly seq scheme.pdb seq num: 759
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,326
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 326
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 326
pdbx poly seq scheme.pdb seq num: 760
pdbx poly seq scheme.pdb strand id: B

B,1,THR,327
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 327
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 327
pdbx poly seq scheme.pdb seq num: 761
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,328
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 328
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 328
pdbx poly seq scheme.pdb seq num: 762
pdbx poly seq scheme.pdb strand id: B

B,1,THR,329
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: THR
pdbx poly seq scheme.seq id: 329
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 329
pdbx poly seq scheme.pdb seq num: 763
pdbx poly seq scheme.pdb strand id: B

B,1,TRP,330
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: TRP
pdbx poly seq scheme.seq id: 330
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 330
pdbx poly seq scheme.pdb seq num: 764
pdbx poly seq scheme.pdb strand id: B

B,1,ILE,331
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ILE
pdbx poly seq scheme.seq id: 331
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 331
pdbx poly seq scheme.pdb seq num: 765
pdbx poly seq scheme.pdb strand id: B

B,1,SER,332
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 332
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 332
pdbx poly seq scheme.pdb seq num: 766
pdbx poly seq scheme.pdb strand id: B

B,1,SER,333
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 333
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 333
pdbx poly seq scheme.pdb seq num: 767
pdbx poly seq scheme.pdb strand id: B

B,1,PRO,334
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: PRO
pdbx poly seq scheme.seq id: 334
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 334
pdbx poly seq scheme.pdb seq num: 768
pdbx poly seq scheme.pdb strand id: B

B,1,SER,335
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 335
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 335
pdbx poly seq scheme.pdb seq num: 769
pdbx poly seq scheme.pdb strand id: B

B,1,VAL,336
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: VAL
pdbx poly seq scheme.seq id: 336
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 336
pdbx poly seq scheme.pdb seq num: 770
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,337
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 337
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 337
pdbx poly seq scheme.pdb seq num: 771
pdbx poly seq scheme.pdb strand id: B

B,1,GLN,338
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLN
pdbx poly seq scheme.seq id: 338
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 338
pdbx poly seq scheme.pdb seq num: 772
pdbx poly seq scheme.pdb strand id: B

B,1,LYS,339
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: LYS
pdbx poly seq scheme.seq id: 339
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 339
pdbx poly seq scheme.pdb seq num: 773
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,340
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 340
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 340
pdbx poly seq scheme.pdb seq num: 774
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,341
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 341
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 341
pdbx poly seq scheme.pdb seq num: 775
pdbx poly seq scheme.pdb strand id: B

B,1,ALA,342
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ALA
pdbx poly seq scheme.seq id: 342
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 342
pdbx poly seq scheme.pdb seq num: 776
pdbx poly seq scheme.pdb strand id: B

B,1,SER,343
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: SER
pdbx poly seq scheme.seq id: 343
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 343
pdbx poly seq scheme.pdb seq num: 777
pdbx poly seq scheme.pdb strand id: B

B,1,GLU,344
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: GLU
pdbx poly seq scheme.seq id: 344
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 344
pdbx poly seq scheme.pdb seq num: 778
pdbx poly seq scheme.pdb strand id: B

B,1,ASP,345
type: pdbx poly seq scheme
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity poly seq: ,,
reference to struct asym: http://rdf.wwpdb.org/pdb/8DI4/struct_asym/,
pdbx poly seq scheme.asym id: B
pdbx poly seq scheme.entity id: 1
pdbx poly seq scheme.mon id: ASP
pdbx poly seq scheme.seq id: 345
pdbx poly seq scheme.hetero: n
pdbx poly seq scheme.ndb seq num: 345
pdbx poly seq scheme.pdb seq num: 779
pdbx poly seq scheme.pdb strand id: B

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_assembly/1
type: pdbx struct assembly
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct assembly.id: 1
pdbx struct assembly.details: author_defined_assembly
pdbx struct assembly.oligomeric count: 1
pdbx struct assembly.oligomeric details: monomeric

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_assembly/2
type: pdbx struct assembly
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct assembly.id: 2
pdbx struct assembly.details: author_defined_assembly
pdbx struct assembly.oligomeric count: 1
pdbx struct assembly.oligomeric details: monomeric

1,1
type: pdbx struct assembly auth evidence
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to pdbx struct assembly: pdbx struct assembly
pdbx struct assembly auth evidence.assembly id: 1
pdbx struct assembly auth evidence.id: 1
pdbx struct assembly auth evidence.experimental support: none

1,A,C,D,E,I,1
type: pdbx struct assembly gen
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to pdbx struct assembly: pdbx struct assembly
pdbx struct assembly gen.assembly id: 1
pdbx struct assembly gen.asym id list: A,C,D,E,I
pdbx struct assembly gen.oper expression: 1

2,B,F,G,H,J,1
type: pdbx struct assembly gen
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to pdbx struct assembly: pdbx struct assembly
pdbx struct assembly gen.assembly id: 2
pdbx struct assembly gen.asym id list: B,F,G,H,J
pdbx struct assembly gen.oper expression: 1

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/1
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 1
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 519
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 85
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 901
pdbx struct conn angle.ptnr2 label asym id: C
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HIS
pdbx struct conn angle.ptnr3 auth seq id: 553
pdbx struct conn angle.ptnr3 label asym id: A
pdbx struct conn angle.ptnr3 label atom id: NE2
pdbx struct conn angle.ptnr3 label comp id: HIS
pdbx struct conn angle.ptnr3 label seq id: 119
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 95.8

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/2
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 2
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 519
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 85
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 901
pdbx struct conn angle.ptnr2 label asym id: C
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: ASP
pdbx struct conn angle.ptnr3 auth seq id: 554
pdbx struct conn angle.ptnr3 label asym id: A
pdbx struct conn angle.ptnr3 label atom id: OD2
pdbx struct conn angle.ptnr3 label comp id: ASP
pdbx struct conn angle.ptnr3 label seq id: 120
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 74.9

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/3
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 3
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 553
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 119
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 901
pdbx struct conn angle.ptnr2 label asym id: C
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: ASP
pdbx struct conn angle.ptnr3 auth seq id: 554
pdbx struct conn angle.ptnr3 label asym id: A
pdbx struct conn angle.ptnr3 label atom id: OD2
pdbx struct conn angle.ptnr3 label comp id: ASP
pdbx struct conn angle.ptnr3 label seq id: 120
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 91.4

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/4
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 4
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 519
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 85
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 901
pdbx struct conn angle.ptnr2 label asym id: C
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: ASP
pdbx struct conn angle.ptnr3 auth seq id: 664
pdbx struct conn angle.ptnr3 label asym id: A
pdbx struct conn angle.ptnr3 label atom id: OD1
pdbx struct conn angle.ptnr3 label comp id: ASP
pdbx struct conn angle.ptnr3 label seq id: 230
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 97.6

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/5
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 5
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 553
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 119
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 901
pdbx struct conn angle.ptnr2 label asym id: C
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: ASP
pdbx struct conn angle.ptnr3 auth seq id: 664
pdbx struct conn angle.ptnr3 label asym id: A
pdbx struct conn angle.ptnr3 label atom id: OD1
pdbx struct conn angle.ptnr3 label comp id: ASP
pdbx struct conn angle.ptnr3 label seq id: 230
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 84.4

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/6
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 6
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: OD2
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 901
pdbx struct conn angle.ptnr2 label asym id: C
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: ASP
pdbx struct conn angle.ptnr3 auth seq id: 664
pdbx struct conn angle.ptnr3 label asym id: A
pdbx struct conn angle.ptnr3 label atom id: OD1
pdbx struct conn angle.ptnr3 label comp id: ASP
pdbx struct conn angle.ptnr3 label seq id: 230
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 171.0

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/7
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 7
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 519
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 85
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 901
pdbx struct conn angle.ptnr2 label asym id: C
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1003
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 163.1

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/8
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 8
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 553
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 119
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 901
pdbx struct conn angle.ptnr2 label asym id: C
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1003
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 100.6

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/9
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 9
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: OD2
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 901
pdbx struct conn angle.ptnr2 label asym id: C
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1003
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 100.9

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/10
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 10
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 664
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 230
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 901
pdbx struct conn angle.ptnr2 label asym id: C
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1003
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 87.7

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/11
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 11
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1003
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 78.2

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/12
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 12
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1011
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 89.9

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/13
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 13
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 1003
pdbx struct conn angle.ptnr1 label asym id: I
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1011
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 110.7

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/14
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 14
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1013
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 171.9

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/15
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 15
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 1003
pdbx struct conn angle.ptnr1 label asym id: I
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1013
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 106.6

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/16
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 16
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 1011
pdbx struct conn angle.ptnr1 label asym id: I
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1013
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 82.3

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/17
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 17
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1027
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 101.0

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/18
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 18
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 1003
pdbx struct conn angle.ptnr1 label asym id: I
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1027
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 173.2

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/19
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 19
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 1011
pdbx struct conn angle.ptnr1 label asym id: I
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1027
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 76.0

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/20
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 20
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 1013
pdbx struct conn angle.ptnr1 label asym id: I
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1027
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 75.0

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/21
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 21
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: A
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1046
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 102.4

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/22
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 22
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 1003
pdbx struct conn angle.ptnr1 label asym id: I
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1046
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 89.3

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/23
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 23
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 1011
pdbx struct conn angle.ptnr1 label asym id: I
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1046
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 158.5

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/24
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 24
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 1013
pdbx struct conn angle.ptnr1 label asym id: I
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1046
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 84.4

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/25
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 25
pdbx struct conn angle.ptnr1 auth asym id: A
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 1027
pdbx struct conn angle.ptnr1 label asym id: I
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: A
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 902
pdbx struct conn angle.ptnr2 label asym id: D
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: A
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 1046
pdbx struct conn angle.ptnr3 label asym id: I
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 84.3

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/26
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 26
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 519
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 85
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 801
pdbx struct conn angle.ptnr2 label asym id: F
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HIS
pdbx struct conn angle.ptnr3 auth seq id: 553
pdbx struct conn angle.ptnr3 label asym id: B
pdbx struct conn angle.ptnr3 label atom id: NE2
pdbx struct conn angle.ptnr3 label comp id: HIS
pdbx struct conn angle.ptnr3 label seq id: 119
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 93.7

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/27
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 27
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 519
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 85
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 801
pdbx struct conn angle.ptnr2 label asym id: F
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: ASP
pdbx struct conn angle.ptnr3 auth seq id: 554
pdbx struct conn angle.ptnr3 label asym id: B
pdbx struct conn angle.ptnr3 label atom id: OD2
pdbx struct conn angle.ptnr3 label comp id: ASP
pdbx struct conn angle.ptnr3 label seq id: 120
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 88.5

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/28
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 28
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 553
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 119
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 801
pdbx struct conn angle.ptnr2 label asym id: F
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: ASP
pdbx struct conn angle.ptnr3 auth seq id: 554
pdbx struct conn angle.ptnr3 label asym id: B
pdbx struct conn angle.ptnr3 label atom id: OD2
pdbx struct conn angle.ptnr3 label comp id: ASP
pdbx struct conn angle.ptnr3 label seq id: 120
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 99.4

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/29
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 29
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 519
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 85
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 801
pdbx struct conn angle.ptnr2 label asym id: F
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: ASP
pdbx struct conn angle.ptnr3 auth seq id: 664
pdbx struct conn angle.ptnr3 label asym id: B
pdbx struct conn angle.ptnr3 label atom id: OD1
pdbx struct conn angle.ptnr3 label comp id: ASP
pdbx struct conn angle.ptnr3 label seq id: 230
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 91.1

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/30
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 30
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 553
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 119
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 801
pdbx struct conn angle.ptnr2 label asym id: F
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: ASP
pdbx struct conn angle.ptnr3 auth seq id: 664
pdbx struct conn angle.ptnr3 label asym id: B
pdbx struct conn angle.ptnr3 label atom id: OD1
pdbx struct conn angle.ptnr3 label comp id: ASP
pdbx struct conn angle.ptnr3 label seq id: 230
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 82.8

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/31
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 31
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: OD2
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 801
pdbx struct conn angle.ptnr2 label asym id: F
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: ASP
pdbx struct conn angle.ptnr3 auth seq id: 664
pdbx struct conn angle.ptnr3 label asym id: B
pdbx struct conn angle.ptnr3 label atom id: OD1
pdbx struct conn angle.ptnr3 label comp id: ASP
pdbx struct conn angle.ptnr3 label seq id: 230
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 177.7

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/32
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 32
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 519
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 85
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 801
pdbx struct conn angle.ptnr2 label asym id: F
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 914
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 164.8

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/33
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 33
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HIS
pdbx struct conn angle.ptnr1 auth seq id: 553
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: NE2
pdbx struct conn angle.ptnr1 label comp id: HIS
pdbx struct conn angle.ptnr1 label seq id: 119
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 801
pdbx struct conn angle.ptnr2 label asym id: F
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 914
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 101.4

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/34
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 34
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: OD2
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 801
pdbx struct conn angle.ptnr2 label asym id: F
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 914
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 87.2

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/35
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 35
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 664
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 230
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: ZN
pdbx struct conn angle.ptnr2 auth seq id: 801
pdbx struct conn angle.ptnr2 label asym id: F
pdbx struct conn angle.ptnr2 label atom id: ZN
pdbx struct conn angle.ptnr2 label comp id: ZN
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 914
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 92.6

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/36
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 36
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 914
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 90.5

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/37
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 37
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 921
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 85.0

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/38
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 38
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 914
pdbx struct conn angle.ptnr1 label asym id: J
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 921
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 172.6

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/39
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 39
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 922
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 102.8

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/40
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 40
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 914
pdbx struct conn angle.ptnr1 label asym id: J
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 922
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 86.0

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/41
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 41
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 921
pdbx struct conn angle.ptnr1 label asym id: J
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 922
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 89.2

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/42
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 42
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 924
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 82.0

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/43
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 43
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 914
pdbx struct conn angle.ptnr1 label asym id: J
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 924
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 94.4

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/44
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 44
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 921
pdbx struct conn angle.ptnr1 label asym id: J
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 924
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 90.8

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/45
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 45
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 922
pdbx struct conn angle.ptnr1 label asym id: J
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 924
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 175.2

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/46
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 46
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: ASP
pdbx struct conn angle.ptnr1 auth seq id: 554
pdbx struct conn angle.ptnr1 label asym id: B
pdbx struct conn angle.ptnr1 label atom id: OD1
pdbx struct conn angle.ptnr1 label comp id: ASP
pdbx struct conn angle.ptnr1 label seq id: 120
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 930
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 177.2

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/47
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 47
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 914
pdbx struct conn angle.ptnr1 label asym id: J
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 930
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 89.9

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/48
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 48
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 921
pdbx struct conn angle.ptnr1 label asym id: J
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
pdbx struct conn angle.ptnr2 label comp id: MG
pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 930
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 94.8

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/49
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 49
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 922
pdbx struct conn angle.ptnr1 label asym id: J
pdbx struct conn angle.ptnr1 label atom id: O
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pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
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pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
pdbx struct conn angle.ptnr3 auth comp id: HOH
pdbx struct conn angle.ptnr3 auth seq id: 930
pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 80.0

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_conn_angle/50
type: pdbx struct conn angle
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct conn angle.id: 50
pdbx struct conn angle.ptnr1 auth asym id: B
pdbx struct conn angle.ptnr1 auth comp id: HOH
pdbx struct conn angle.ptnr1 auth seq id: 924
pdbx struct conn angle.ptnr1 label asym id: J
pdbx struct conn angle.ptnr1 label atom id: O
pdbx struct conn angle.ptnr1 label comp id: HOH
pdbx struct conn angle.ptnr1 symmetry: 1_555
pdbx struct conn angle.ptnr2 auth asym id: B
pdbx struct conn angle.ptnr2 auth comp id: MG
pdbx struct conn angle.ptnr2 auth seq id: 802
pdbx struct conn angle.ptnr2 label asym id: G
pdbx struct conn angle.ptnr2 label atom id: MG
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pdbx struct conn angle.ptnr2 symmetry: 1_555
pdbx struct conn angle.ptnr3 auth asym id: B
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pdbx struct conn angle.ptnr3 label asym id: J
pdbx struct conn angle.ptnr3 label atom id: O
pdbx struct conn angle.ptnr3 label comp id: HOH
pdbx struct conn angle.ptnr3 symmetry: 1_555
pdbx struct conn angle.value: 95.2

http://rdf.wwpdb.org/pdb/8DI4/pdbx_struct_oper_list/1
type: pdbx struct oper list
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx struct oper list.id: 1
pdbx struct oper list.matrix11: 1.0000000000
pdbx struct oper list.matrix12: 0.0000000000
pdbx struct oper list.matrix13: 0.0000000000
pdbx struct oper list.matrix21: 0.0000000000
pdbx struct oper list.matrix22: 1.0000000000
pdbx struct oper list.matrix23: 0.0000000000
pdbx struct oper list.matrix31: 0.0000000000
pdbx struct oper list.matrix32: 0.0000000000
pdbx struct oper list.matrix33: 1.0000000000
pdbx struct oper list.name: 1_555
pdbx struct oper list.symmetry operation: x,y,z
pdbx struct oper list.type: identity operation
pdbx struct oper list.vector1: 0.0000000000
pdbx struct oper list.vector2: 0.0000000000
pdbx struct oper list.vector3: 0.0000000000

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/1
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: VAL
pdbx unobs or zero occ atoms.id: 1
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
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pdbx unobs or zero occ atoms.auth comp id: VAL
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pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CG1
pdbx unobs or zero occ atoms.label comp id: VAL
pdbx unobs or zero occ atoms.label seq id: 22
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/2
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: VAL
pdbx unobs or zero occ atoms.id: 2
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
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pdbx unobs or zero occ atoms.auth comp id: VAL
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pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CG2
pdbx unobs or zero occ atoms.label comp id: VAL
pdbx unobs or zero occ atoms.label seq id: 22
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/3
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
pdbx unobs or zero occ atoms.id: 3
pdbx unobs or zero occ atoms.pdb model num: 1
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pdbx unobs or zero occ atoms.label asym id: A
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pdbx unobs or zero occ atoms.label seq id: 62
pdbx unobs or zero occ atoms.occupancy flag: 1
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/4
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
pdbx unobs or zero occ atoms.id: 4
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pdbx unobs or zero occ atoms.auth seq id: 496
pdbx unobs or zero occ atoms.label asym id: A
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/5
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
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pdbx unobs or zero occ atoms.auth seq id: 496
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pdbx unobs or zero occ atoms.label atom id: OE1
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pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/6
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
pdbx unobs or zero occ atoms.id: 6
pdbx unobs or zero occ atoms.pdb model num: 1
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pdbx unobs or zero occ atoms.auth atom id: OE2
pdbx unobs or zero occ atoms.auth comp id: GLU
pdbx unobs or zero occ atoms.auth seq id: 496
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: OE2
pdbx unobs or zero occ atoms.label comp id: GLU
pdbx unobs or zero occ atoms.label seq id: 62
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/7
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 7
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CG
pdbx unobs or zero occ atoms.auth comp id: LYS
pdbx unobs or zero occ atoms.auth seq id: 507
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CG
pdbx unobs or zero occ atoms.label comp id: LYS
pdbx unobs or zero occ atoms.label seq id: 73
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/8
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 8
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: CD
pdbx unobs or zero occ atoms.auth comp id: LYS
pdbx unobs or zero occ atoms.auth seq id: 507
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CD
pdbx unobs or zero occ atoms.label comp id: LYS
pdbx unobs or zero occ atoms.label seq id: 73
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/9
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
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pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
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pdbx unobs or zero occ atoms.auth comp id: LYS
pdbx unobs or zero occ atoms.auth seq id: 507
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CE
pdbx unobs or zero occ atoms.label comp id: LYS
pdbx unobs or zero occ atoms.label seq id: 73
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/10
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
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pdbx unobs or zero occ atoms.auth comp id: LYS
pdbx unobs or zero occ atoms.auth seq id: 507
pdbx unobs or zero occ atoms.label asym id: A
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pdbx unobs or zero occ atoms.label comp id: LYS
pdbx unobs or zero occ atoms.label seq id: 73
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/11
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ARG
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pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
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pdbx unobs or zero occ atoms.auth comp id: ARG
pdbx unobs or zero occ atoms.auth seq id: 511
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CG
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 77
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/12
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 12
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
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pdbx unobs or zero occ atoms.auth seq id: 511
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CD
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 77
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/13
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ARG
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pdbx unobs or zero occ atoms.auth asym id: A
pdbx unobs or zero occ atoms.auth atom id: NE
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pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: NE
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pdbx unobs or zero occ atoms.label seq id: 77
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pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/14
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ARG
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pdbx unobs or zero occ atoms.auth seq id: 511
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: CZ
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pdbx unobs or zero occ atoms.label seq id: 77
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/15
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ARG
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pdbx unobs or zero occ atoms.auth seq id: 511
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: NH1
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/16
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ARG
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/17
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/18
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/19
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/20
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
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pdbx unobs or zero occ atoms.auth seq id: 596
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pdbx unobs or zero occ atoms.label seq id: 162
pdbx unobs or zero occ atoms.occupancy flag: 1
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/21
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
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pdbx unobs or zero occ atoms.auth seq id: 633
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pdbx unobs or zero occ atoms.label seq id: 199
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/22
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
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pdbx unobs or zero occ atoms.auth seq id: 633
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pdbx unobs or zero occ atoms.label seq id: 199
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pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/23
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
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pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
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pdbx unobs or zero occ atoms.auth comp id: LYS
pdbx unobs or zero occ atoms.auth seq id: 633
pdbx unobs or zero occ atoms.label asym id: A
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pdbx unobs or zero occ atoms.label seq id: 199
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/24
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 24
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
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pdbx unobs or zero occ atoms.auth comp id: LYS
pdbx unobs or zero occ atoms.auth seq id: 633
pdbx unobs or zero occ atoms.label asym id: A
pdbx unobs or zero occ atoms.label atom id: NZ
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pdbx unobs or zero occ atoms.label seq id: 199
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/25
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 25
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
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pdbx unobs or zero occ atoms.label asym id: A
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pdbx unobs or zero occ atoms.label comp id: GLN
pdbx unobs or zero occ atoms.label seq id: 206
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/26
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 26
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: A
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pdbx unobs or zero occ atoms.auth seq id: 640
pdbx unobs or zero occ atoms.label asym id: A
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pdbx unobs or zero occ atoms.label seq id: 206
pdbx unobs or zero occ atoms.occupancy flag: 1
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/27
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 27
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pdbx unobs or zero occ atoms.auth seq id: 640
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pdbx unobs or zero occ atoms.label seq id: 206
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pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/28
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 28
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pdbx unobs or zero occ atoms.label seq id: 206
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/29
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 29
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: B
pdbx unobs or zero occ atoms.auth atom id: CG
pdbx unobs or zero occ atoms.auth comp id: GLN
pdbx unobs or zero occ atoms.auth seq id: 447
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pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/30
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 30
pdbx unobs or zero occ atoms.pdb model num: 1
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pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/31
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 31
pdbx unobs or zero occ atoms.pdb model num: 1
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pdbx unobs or zero occ atoms.label atom id: OE1
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pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/32
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLN
pdbx unobs or zero occ atoms.id: 32
pdbx unobs or zero occ atoms.pdb model num: 1
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pdbx unobs or zero occ atoms.auth atom id: NE2
pdbx unobs or zero occ atoms.auth comp id: GLN
pdbx unobs or zero occ atoms.auth seq id: 447
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pdbx unobs or zero occ atoms.label seq id: 13
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pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/33
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
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pdbx unobs or zero occ atoms.id: 33
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: B
pdbx unobs or zero occ atoms.auth atom id: CG
pdbx unobs or zero occ atoms.auth comp id: ARG
pdbx unobs or zero occ atoms.auth seq id: 457
pdbx unobs or zero occ atoms.label asym id: B
pdbx unobs or zero occ atoms.label atom id: CG
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 23
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/34
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 34
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: B
pdbx unobs or zero occ atoms.auth atom id: CD
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pdbx unobs or zero occ atoms.auth seq id: 457
pdbx unobs or zero occ atoms.label asym id: B
pdbx unobs or zero occ atoms.label atom id: CD
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 23
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/35
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 35
pdbx unobs or zero occ atoms.pdb model num: 1
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pdbx unobs or zero occ atoms.auth atom id: NE
pdbx unobs or zero occ atoms.auth comp id: ARG
pdbx unobs or zero occ atoms.auth seq id: 457
pdbx unobs or zero occ atoms.label asym id: B
pdbx unobs or zero occ atoms.label atom id: NE
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 23
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/36
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 36
pdbx unobs or zero occ atoms.pdb model num: 1
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pdbx unobs or zero occ atoms.auth atom id: CZ
pdbx unobs or zero occ atoms.auth comp id: ARG
pdbx unobs or zero occ atoms.auth seq id: 457
pdbx unobs or zero occ atoms.label asym id: B
pdbx unobs or zero occ atoms.label atom id: CZ
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 23
pdbx unobs or zero occ atoms.occupancy flag: 1
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/37
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 37
pdbx unobs or zero occ atoms.pdb model num: 1
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pdbx unobs or zero occ atoms.auth seq id: 457
pdbx unobs or zero occ atoms.label asym id: B
pdbx unobs or zero occ atoms.label atom id: NH1
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 23
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/38
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ARG
pdbx unobs or zero occ atoms.id: 38
pdbx unobs or zero occ atoms.pdb model num: 1
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pdbx unobs or zero occ atoms.auth seq id: 457
pdbx unobs or zero occ atoms.label asym id: B
pdbx unobs or zero occ atoms.label atom id: NH2
pdbx unobs or zero occ atoms.label comp id: ARG
pdbx unobs or zero occ atoms.label seq id: 23
pdbx unobs or zero occ atoms.occupancy flag: 1
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/39
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 39
pdbx unobs or zero occ atoms.pdb model num: 1
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pdbx unobs or zero occ atoms.auth seq id: 460
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pdbx unobs or zero occ atoms.label seq id: 26
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/40
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
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pdbx unobs or zero occ atoms.label seq id: 26
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/41
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 41
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pdbx unobs or zero occ atoms.auth seq id: 460
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/42
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
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pdbx unobs or zero occ atoms.auth seq id: 460
pdbx unobs or zero occ atoms.label asym id: B
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pdbx unobs or zero occ atoms.label seq id: 26
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/43
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ASP
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pdbx unobs or zero occ atoms.pdb model num: 1
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/44
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ASP
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/45
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/46
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/47
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/48
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/49
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/50
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 50
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pdbx unobs or zero occ atoms.auth seq id: 633
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pdbx unobs or zero occ atoms.label seq id: 199
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/51
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 51
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pdbx unobs or zero occ atoms.auth seq id: 633
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pdbx unobs or zero occ atoms.label seq id: 199
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http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/52
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 52
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pdbx unobs or zero occ atoms.label seq id: 199
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_atoms/53
type: pdbx unobs or zero occ atoms
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
pdbx unobs or zero occ atoms.id: 53
pdbx unobs or zero occ atoms.pdb model num: 1
pdbx unobs or zero occ atoms.auth asym id: B
pdbx unobs or zero occ atoms.auth atom id: NZ
pdbx unobs or zero occ atoms.auth comp id: LYS
pdbx unobs or zero occ atoms.auth seq id: 633
pdbx unobs or zero occ atoms.label asym id: B
pdbx unobs or zero occ atoms.label atom id: NZ
pdbx unobs or zero occ atoms.label comp id: LYS
pdbx unobs or zero occ atoms.label seq id: 199
pdbx unobs or zero occ atoms.occupancy flag: 1
pdbx unobs or zero occ atoms.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/1
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLY
pdbx unobs or zero occ residues.id: 1
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLY
pdbx unobs or zero occ residues.auth seq id: 435
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLY
pdbx unobs or zero occ residues.label seq id: 1
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/2
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 2
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 436
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 2
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/3
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: HIS
pdbx unobs or zero occ residues.id: 3
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: HIS
pdbx unobs or zero occ residues.auth seq id: 437
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: HIS
pdbx unobs or zero occ residues.label seq id: 3
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/4
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: MET
pdbx unobs or zero occ residues.id: 4
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: MET
pdbx unobs or zero occ residues.auth seq id: 438
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: MET
pdbx unobs or zero occ residues.label seq id: 4
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/5
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 5
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 759
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 325
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/6
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 6
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 760
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 326
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/7
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: THR
pdbx unobs or zero occ residues.id: 7
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: THR
pdbx unobs or zero occ residues.auth seq id: 761
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: THR
pdbx unobs or zero occ residues.label seq id: 327
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/8
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 8
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 762
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 328
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/9
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: THR
pdbx unobs or zero occ residues.id: 9
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: THR
pdbx unobs or zero occ residues.auth seq id: 763
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: THR
pdbx unobs or zero occ residues.label seq id: 329
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/10
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: TRP
pdbx unobs or zero occ residues.id: 10
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: TRP
pdbx unobs or zero occ residues.auth seq id: 764
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: TRP
pdbx unobs or zero occ residues.label seq id: 330
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/11
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ILE
pdbx unobs or zero occ residues.id: 11
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ILE
pdbx unobs or zero occ residues.auth seq id: 765
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ILE
pdbx unobs or zero occ residues.label seq id: 331
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/12
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 12
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 766
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 332
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/13
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 13
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 767
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 333
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/14
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: PRO
pdbx unobs or zero occ residues.id: 14
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: PRO
pdbx unobs or zero occ residues.auth seq id: 768
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: PRO
pdbx unobs or zero occ residues.label seq id: 334
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/15
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 15
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 769
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 335
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/16
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: VAL
pdbx unobs or zero occ residues.id: 16
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: VAL
pdbx unobs or zero occ residues.auth seq id: 770
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: VAL
pdbx unobs or zero occ residues.label seq id: 336
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/17
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 17
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 771
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 337
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/18
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLN
pdbx unobs or zero occ residues.id: 18
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLN
pdbx unobs or zero occ residues.auth seq id: 772
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLN
pdbx unobs or zero occ residues.label seq id: 338
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/19
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
pdbx unobs or zero occ residues.id: 19
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: LYS
pdbx unobs or zero occ residues.auth seq id: 773
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: LYS
pdbx unobs or zero occ residues.label seq id: 339
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/20
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 20
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 774
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 340
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/21
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 21
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 775
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 341
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/22
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 22
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 776
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 342
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/23
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 23
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 777
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 343
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/24
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 24
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 778
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 344
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/25
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 25
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: A
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 779
pdbx unobs or zero occ residues.label asym id: A
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 345
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/26
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLY
pdbx unobs or zero occ residues.id: 26
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: GLY
pdbx unobs or zero occ residues.auth seq id: 435
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: GLY
pdbx unobs or zero occ residues.label seq id: 1
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/27
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 27
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 436
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 2
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/28
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 28
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 759
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 325
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/29
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 29
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 760
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 326
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/30
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: THR
pdbx unobs or zero occ residues.id: 30
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: THR
pdbx unobs or zero occ residues.auth seq id: 761
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: THR
pdbx unobs or zero occ residues.label seq id: 327
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/31
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 31
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 762
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 328
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/32
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: THR
pdbx unobs or zero occ residues.id: 32
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: THR
pdbx unobs or zero occ residues.auth seq id: 763
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: THR
pdbx unobs or zero occ residues.label seq id: 329
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/33
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: TRP
pdbx unobs or zero occ residues.id: 33
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: TRP
pdbx unobs or zero occ residues.auth seq id: 764
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: TRP
pdbx unobs or zero occ residues.label seq id: 330
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/34
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ILE
pdbx unobs or zero occ residues.id: 34
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: ILE
pdbx unobs or zero occ residues.auth seq id: 765
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: ILE
pdbx unobs or zero occ residues.label seq id: 331
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/35
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 35
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 766
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 332
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/36
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 36
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 767
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 333
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/37
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: PRO
pdbx unobs or zero occ residues.id: 37
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: PRO
pdbx unobs or zero occ residues.auth seq id: 768
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: PRO
pdbx unobs or zero occ residues.label seq id: 334
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/38
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 38
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 769
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 335
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/39
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: VAL
pdbx unobs or zero occ residues.id: 39
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: VAL
pdbx unobs or zero occ residues.auth seq id: 770
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: VAL
pdbx unobs or zero occ residues.label seq id: 336
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/40
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 40
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 771
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 337
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/41
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLN
pdbx unobs or zero occ residues.id: 41
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: GLN
pdbx unobs or zero occ residues.auth seq id: 772
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: GLN
pdbx unobs or zero occ residues.label seq id: 338
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/42
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: LYS
pdbx unobs or zero occ residues.id: 42
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: LYS
pdbx unobs or zero occ residues.auth seq id: 773
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: LYS
pdbx unobs or zero occ residues.label seq id: 339
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/43
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 43
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 774
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 340
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/44
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 44
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 775
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 341
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/45
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ALA
pdbx unobs or zero occ residues.id: 45
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: ALA
pdbx unobs or zero occ residues.auth seq id: 776
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: ALA
pdbx unobs or zero occ residues.label seq id: 342
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/46
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: SER
pdbx unobs or zero occ residues.id: 46
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: SER
pdbx unobs or zero occ residues.auth seq id: 777
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: SER
pdbx unobs or zero occ residues.label seq id: 343
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/47
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: GLU
pdbx unobs or zero occ residues.id: 47
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: GLU
pdbx unobs or zero occ residues.auth seq id: 778
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: GLU
pdbx unobs or zero occ residues.label seq id: 344
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_unobs_or_zero_occ_residues/48
type: pdbx unobs or zero occ residues
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to chem comp: ASP
pdbx unobs or zero occ residues.id: 48
pdbx unobs or zero occ residues.pdb model num: 1
pdbx unobs or zero occ residues.auth asym id: B
pdbx unobs or zero occ residues.auth comp id: ASP
pdbx unobs or zero occ residues.auth seq id: 779
pdbx unobs or zero occ residues.label asym id: B
pdbx unobs or zero occ residues.label comp id: ASP
pdbx unobs or zero occ residues.label seq id: 345
pdbx unobs or zero occ residues.occupancy flag: 1
pdbx unobs or zero occ residues.polymer flag: Y

http://rdf.wwpdb.org/pdb/8DI4/pdbx_validate_torsion/1
type: pdbx validate torsion
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx validate torsion.id: 1
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: ARG
pdbx validate torsion.auth seq id: 511
pdbx validate torsion.phi: -80.23
pdbx validate torsion.psi: 38.65

http://rdf.wwpdb.org/pdb/8DI4/pdbx_validate_torsion/2
type: pdbx validate torsion
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx validate torsion.id: 2
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: ASN
pdbx validate torsion.auth seq id: 534
pdbx validate torsion.phi: -142.22
pdbx validate torsion.psi: 30.84

http://rdf.wwpdb.org/pdb/8DI4/pdbx_validate_torsion/3
type: pdbx validate torsion
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx validate torsion.id: 3
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: SER
pdbx validate torsion.auth seq id: 579
pdbx validate torsion.phi: 37.62
pdbx validate torsion.psi: 48.54

http://rdf.wwpdb.org/pdb/8DI4/pdbx_validate_torsion/4
type: pdbx validate torsion
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx validate torsion.id: 4
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: ASN
pdbx validate torsion.auth seq id: 599
pdbx validate torsion.phi: -67.42
pdbx validate torsion.psi: 92.26

http://rdf.wwpdb.org/pdb/8DI4/pdbx_validate_torsion/5
type: pdbx validate torsion
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx validate torsion.id: 5
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: A
pdbx validate torsion.auth comp id: THR
pdbx validate torsion.auth seq id: 603
pdbx validate torsion.phi: -69.50
pdbx validate torsion.psi: 0.38

http://rdf.wwpdb.org/pdb/8DI4/pdbx_validate_torsion/6
type: pdbx validate torsion
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx validate torsion.id: 6
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: B
pdbx validate torsion.auth comp id: TYR
pdbx validate torsion.auth seq id: 514
pdbx validate torsion.phi: -132.48
pdbx validate torsion.psi: -50.68

http://rdf.wwpdb.org/pdb/8DI4/pdbx_validate_torsion/7
type: pdbx validate torsion
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
pdbx validate torsion.id: 7
pdbx validate torsion.pdb model num: 1
pdbx validate torsion.auth asym id: B
pdbx validate torsion.auth comp id: SER
pdbx validate torsion.auth seq id: 577
pdbx validate torsion.phi: -61.73
pdbx validate torsion.psi: -71.25

8DI4,X-RAY DIFFRACTION
type: refine
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entry: entry
refine.entry id: 8DI4
refine.pdbx refine id: X-RAY DIFFRACTION
refine.b iso max: 89.820
refine.b iso mean: 48.4500
refine.b iso min: 20.390
refine.aniso B11: -20.5169
refine.aniso B12: 0.0000
refine.aniso B13: 0.0000
refine.aniso B22: 15.3043
refine.aniso B23: 0.0000
refine.aniso B33: 5.2126
refine.correlation coeff fo to fc: 0.9090
refine.correlation coeff fo to fc free: 0.8810
refine.ls r factor r free: 0.2946
refine.ls r factor r work: 0.2499
refine.ls r factor obs: 0.2521
refine.ls d res high: 2.0160
refine.ls d res low: 78.8700
refine.ls number reflns r free: 2102
refine.ls number reflns obs: 41973
refine.ls percent reflns r free: 5.0100
refine.ls percent reflns obs: 97.2000
refine.overall SU r cruickshank DPI: 0.2560
refine.pdbx r free selection details: RANDOM
refine.pdbx diffrn id: 1
refine.pdbx ls cross valid method: THROUGHOUT
refine.pdbx ls sigma f: 0.000
refine.pdbx method to determine struct: MOLECULAR REPLACEMENT
refine.pdbx overall SU r blow DPI: 0.2560
refine.pdbx overall SU r free blow DPI: 0.2110
refine.pdbx overall SU r free cruickshank DPI: 0.2120
refine.pdbx starting model: 5c2h

8DI4,X-RAY DIFFRACTION
type: refine analyze
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entry: entry
refine analyze.entry id: 8DI4
refine analyze.pdbx refine id: X-RAY DIFFRACTION
refine analyze.luzzati coordinate error obs: 0.360

final,X-RAY DIFFRACTION
type: refine hist
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine hist.cycle id: final
refine hist.pdbx refine id: X-RAY DIFFRACTION
refine hist.d res high: 2.0160
refine hist.d res low: 78.8700
refine hist.number atoms solvent: 105
refine hist.number atoms total: 5314
refine hist.pdbx b iso mean ligand: 35.66
refine hist.pdbx b iso mean solvent: 41.73
refine hist.pdbx number atoms ligand: 58
refine hist.pdbx number atoms nucleic acid: 0
refine hist.pdbx number atoms protein: 5151
refine hist.pdbx number residues total: 642

X-RAY DIFFRACTION,t dihedral angle d
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_dihedral_angle_d
refine ls restr.number: 1841
refine ls restr.pdbx restraint function: SINUSOIDAL
refine ls restr.weight: 2.000

X-RAY DIFFRACTION,t trig c planes
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_trig_c_planes

X-RAY DIFFRACTION,t gen planes
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_gen_planes
refine ls restr.number: 931
refine ls restr.pdbx restraint function: HARMONIC
refine ls restr.weight: 5.000

X-RAY DIFFRACTION,t it
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_it
refine ls restr.number: 5341
refine ls restr.pdbx restraint function: HARMONIC
refine ls restr.weight: 10.000

X-RAY DIFFRACTION,t nbd
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_nbd

X-RAY DIFFRACTION,t improper torsion
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_improper_torsion

X-RAY DIFFRACTION,t pseud angle
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_pseud_angle

X-RAY DIFFRACTION,t chiral improper torsion
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_chiral_improper_torsion
refine ls restr.number: 696
refine ls restr.pdbx restraint function: SEMIHARMONIC
refine ls restr.weight: 5.000

X-RAY DIFFRACTION,t sum occupancies
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_sum_occupancies

X-RAY DIFFRACTION,t utility distance
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_utility_distance

X-RAY DIFFRACTION,t utility angle
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_utility_angle

X-RAY DIFFRACTION,t utility torsion
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_utility_torsion

X-RAY DIFFRACTION,t ideal dist contact
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_ideal_dist_contact
refine ls restr.number: 4613
refine ls restr.pdbx restraint function: SEMIHARMONIC
refine ls restr.weight: 4.000

X-RAY DIFFRACTION,t bond d
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_bond_d
refine ls restr.dev ideal: 0.008
refine ls restr.number: 5341
refine ls restr.pdbx restraint function: HARMONIC
refine ls restr.weight: 2.000

X-RAY DIFFRACTION,t angle deg
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_angle_deg
refine ls restr.dev ideal: 0.890
refine ls restr.number: 7245
refine ls restr.pdbx restraint function: HARMONIC
refine ls restr.weight: 2.000

X-RAY DIFFRACTION,t omega torsion
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_omega_torsion
refine ls restr.dev ideal: 2.710

X-RAY DIFFRACTION,t other torsion
type: refine ls restr
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls restr.pdbx refine id: X-RAY DIFFRACTION
refine ls restr.type: t_other_torsion
refine ls restr.dev ideal: 17.500

2.0200,X-RAY DIFFRACTION
type: refine ls shell
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
refine ls shell.d res high: 2.0200
refine ls shell.pdbx refine id: X-RAY DIFFRACTION
refine ls shell.r factor r free: 0.4411
refine ls shell.r factor r free error: 0.0000
refine ls shell.r factor r work: 0.3649
refine ls shell.r factor all: 0.3690
refine ls shell.d res low: 2.0300
refine ls shell.number reflns r free: 47
refine ls shell.number reflns r work: 793
refine ls shell.number reflns all: 840
refine ls shell.pdbx total number of bins used: 51
refine ls shell.percent reflns r free: 5.6000
refine ls shell.percent reflns obs: 97.8400

http://rdf.wwpdb.org/pdb/8DI4/reflns/1
type: reflns
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entry: 8DI4
reflns.pdbx ordinal: 1
reflns.b iso wilson estimate: 41.640
reflns.d resolution high: 2.016
reflns.d resolution low: 78.875
reflns.entry id: 8DI4
reflns.number obs: 41974
reflns.pdbx CC half: 1.000
reflns.pdbx rmerge i obs: 0.046
reflns.pdbx rrim i all: 0.051
reflns.pdbx diffrn id: 1
reflns.pdbx net i over sigma i: 19.6
reflns.pdbx redundancy: 6.4
reflns.percent possible obs: 97.3

http://rdf.wwpdb.org/pdb/8DI4/reflns_shell/1
type: reflns shell
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reflns shell.pdbx ordinal: 1
reflns shell.rmerge i obs: 0.811
reflns shell.d res high: 2.016
reflns shell.d res low: 2.051
reflns shell.mean i over sig i obs: 2.2
reflns shell.number unique obs: 14248
reflns shell.pdbx CC half: 0.894
reflns shell.pdbx rrim i all: 0.880
reflns shell.pdbx diffrn id: 1

http://rdf.wwpdb.org/pdb/8DI4/software/1
type: software
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
software.pdbx ordinal: 1
software.classification: data scaling
software.name: autoPROC
software.version: 1.1.7

http://rdf.wwpdb.org/pdb/8DI4/software/2
type: software
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
software.pdbx ordinal: 2
software.classification: refinement
software.name: BUSTER
software.version: 2.11.8 (16-JUL-2021)

http://rdf.wwpdb.org/pdb/8DI4/software/3
type: software
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
software.pdbx ordinal: 3
software.classification: data extraction
software.name: PDB_EXTRACT
software.version: 3.27

http://rdf.wwpdb.org/pdb/8DI4/software/4
type: software
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
software.pdbx ordinal: 4
software.classification: data reduction
software.name: autoPROC
software.version: 1.1.7

http://rdf.wwpdb.org/pdb/8DI4/software/5
type: software
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
software.pdbx ordinal: 5
software.classification: phasing
software.name: autoBUSTER
software.version: 1.1.7

8DI4
type: struct
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entry: entry
struct.entry id: 8DI4
struct.pdbx CASP flag: N
struct.title: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia

http://rdf.wwpdb.org/pdb/8DI4/struct_asym/A
type: struct asym
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: http://rdf.wwpdb.org/pdb/8DI4/entity/1
struct asym.id: A
struct asym.entity id: 1
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

struct_asymUnique_1
type: struct asym

http://rdf.wwpdb.org/pdb/8DI4/struct_asym/B
type: struct asym
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: http://rdf.wwpdb.org/pdb/8DI4/entity/1
struct asym.id: B
struct asym.entity id: 1
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

struct_asymUnique_1
type: struct asym

http://rdf.wwpdb.org/pdb/8DI4/struct_asym/C
type: struct asym
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: http://rdf.wwpdb.org/pdb/8DI4/entity/2
struct asym.id: C
struct asym.entity id: 2
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

struct_asymUnique_1
type: struct asym

http://rdf.wwpdb.org/pdb/8DI4/struct_asym/D
type: struct asym
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: http://rdf.wwpdb.org/pdb/8DI4/entity/3
struct asym.id: D
struct asym.entity id: 3
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

struct_asymUnique_1
type: struct asym

http://rdf.wwpdb.org/pdb/8DI4/struct_asym/E
type: struct asym
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: http://rdf.wwpdb.org/pdb/8DI4/entity/4
struct asym.id: E
struct asym.entity id: 4
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

struct_asymUnique_1
type: struct asym

http://rdf.wwpdb.org/pdb/8DI4/struct_asym/F
type: struct asym
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: http://rdf.wwpdb.org/pdb/8DI4/entity/2
struct asym.id: F
struct asym.entity id: 2
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

struct_asymUnique_1
type: struct asym

http://rdf.wwpdb.org/pdb/8DI4/struct_asym/G
type: struct asym
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: http://rdf.wwpdb.org/pdb/8DI4/entity/3
struct asym.id: G
struct asym.entity id: 3
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

struct_asymUnique_1
type: struct asym

http://rdf.wwpdb.org/pdb/8DI4/struct_asym/H
type: struct asym
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: http://rdf.wwpdb.org/pdb/8DI4/entity/4
struct asym.id: H
struct asym.entity id: 4
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

struct_asymUnique_1
type: struct asym

http://rdf.wwpdb.org/pdb/8DI4/struct_asym/I
type: struct asym
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: http://rdf.wwpdb.org/pdb/8DI4/entity/5
struct asym.id: I
struct asym.entity id: 5
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

struct_asymUnique_1
type: struct asym

http://rdf.wwpdb.org/pdb/8DI4/struct_asym/J
type: struct asym
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: http://rdf.wwpdb.org/pdb/8DI4/entity/5
struct asym.id: J
struct asym.entity id: 5
struct asym.pdbx blank PDB chainid flag: N
struct asym.pdbx modified: N

struct_asymUnique_1
type: struct asym

HELX P1
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P1
struct conf.beg auth asym id: A
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 442
struct conf.beg label asym id: A
struct conf.beg label comp id: THR
struct conf.beg label seq id: 8
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 451
struct conf.end label asym id: A
struct conf.end label comp id: GLN
struct conf.end label seq id: 17
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA1
struct conf.pdbx PDB helix length: 10

HELX P
referenced by struct conf: HELX P1
referenced by struct conf: HELX P2
referenced by struct conf: HELX P3
referenced by struct conf: HELX P4
referenced by struct conf: HELX P5
referenced by struct conf: HELX P6
referenced by struct conf: HELX P7
referenced by struct conf: HELX P8
referenced by struct conf: HELX P9
referenced by struct conf: HELX P10
referenced by struct conf: HELX P11
referenced by struct conf: HELX P12
referenced by struct conf: HELX P13
referenced by struct conf: HELX P14
referenced by struct conf: HELX P15
referenced by struct conf: HELX P16
referenced by struct conf: HELX P17
referenced by struct conf: HELX P18
referenced by struct conf: HELX P19
referenced by struct conf: HELX P20
referenced by struct conf: HELX P21
referenced by struct conf: HELX P22
referenced by struct conf: HELX P23
referenced by struct conf: HELX P24
referenced by struct conf: HELX P25
referenced by struct conf: HELX P26
referenced by struct conf: HELX P27
referenced by struct conf: HELX P28
referenced by struct conf: HELX P29
referenced by struct conf: HELX P30
referenced by struct conf: HELX P31
referenced by struct conf: HELX P32
referenced by struct conf: HELX P33
referenced by struct conf: HELX P34
referenced by struct conf: HELX P35
referenced by struct conf: HELX P36
referenced by struct conf: HELX P37
referenced by struct conf: HELX P38
referenced by struct conf: HELX P39
type: struct conf type
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
struct conf type.id: HELX_P

HELX P2
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P2
struct conf.beg auth asym id: A
struct conf.beg auth comp id: PRO
struct conf.beg auth seq id: 455
struct conf.beg label asym id: A
struct conf.beg label comp id: PRO
struct conf.beg label seq id: 21
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ILE
struct conf.end auth seq id: 462
struct conf.end label asym id: A
struct conf.end label comp id: ILE
struct conf.end label seq id: 28
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA2
struct conf.pdbx PDB helix length: 8

HELX P3
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P3
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ILE
struct conf.beg auth seq id: 469
struct conf.beg label asym id: A
struct conf.beg label comp id: ILE
struct conf.beg label seq id: 35
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ASN
struct conf.end auth seq id: 474
struct conf.end label asym id: A
struct conf.end label comp id: ASN
struct conf.end label seq id: 40
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AA3
struct conf.pdbx PDB helix length: 6

HELX P4
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P4
struct conf.beg auth asym id: A
struct conf.beg auth comp id: MET
struct conf.beg auth seq id: 475
struct conf.beg label asym id: A
struct conf.beg label comp id: MET
struct conf.beg label seq id: 41
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 489
struct conf.end label asym id: A
struct conf.end label comp id: GLY
struct conf.end label seq id: 55
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA4
struct conf.pdbx PDB helix length: 15

HELX P5
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P5
struct conf.beg auth asym id: A
struct conf.beg auth comp id: GLU
struct conf.beg auth seq id: 494
struct conf.beg label asym id: A
struct conf.beg label comp id: GLU
struct conf.beg label seq id: 60
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LYS
struct conf.end auth seq id: 507
struct conf.end label asym id: A
struct conf.end label comp id: LYS
struct conf.end label seq id: 73
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA5
struct conf.pdbx PDB helix length: 14

HELX P6
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P6
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASN
struct conf.beg auth seq id: 516
struct conf.beg label asym id: A
struct conf.beg label comp id: ASN
struct conf.beg label seq id: 82
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ASN
struct conf.end auth seq id: 533
struct conf.end label asym id: A
struct conf.end label comp id: ASN
struct conf.end label seq id: 99
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA6
struct conf.pdbx PDB helix length: 18

HELX P7
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P7
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASN
struct conf.beg auth seq id: 534
struct conf.beg label asym id: A
struct conf.beg label comp id: ASN
struct conf.beg label seq id: 100
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: PHE
struct conf.end auth seq id: 538
struct conf.end label asym id: A
struct conf.end label comp id: PHE
struct conf.end label seq id: 104
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AA7
struct conf.pdbx PDB helix length: 5

HELX P8
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P8
struct conf.beg auth asym id: A
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 539
struct conf.beg label asym id: A
struct conf.beg label comp id: THR
struct conf.beg label seq id: 105
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: HIS
struct conf.end auth seq id: 553
struct conf.end label asym id: A
struct conf.end label comp id: HIS
struct conf.end label seq id: 119
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA8
struct conf.pdbx PDB helix length: 15

HELX P9
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P9
struct conf.beg auth asym id: A
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 561
struct conf.beg label asym id: A
struct conf.beg label comp id: SER
struct conf.beg label seq id: 127
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: PHE
struct conf.end auth seq id: 568
struct conf.end label asym id: A
struct conf.end label comp id: PHE
struct conf.end label seq id: 134
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AA9
struct conf.pdbx PDB helix length: 8

HELX P10
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P10
struct conf.beg auth asym id: A
struct conf.beg auth comp id: HIS
struct conf.beg auth seq id: 570
struct conf.beg label asym id: A
struct conf.beg label comp id: HIS
struct conf.beg label seq id: 136
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: TYR
struct conf.end auth seq id: 576
struct conf.end label asym id: A
struct conf.end label comp id: TYR
struct conf.end label seq id: 142
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB1
struct conf.pdbx PDB helix length: 7

HELX P11
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P11
struct conf.beg auth asym id: A
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 579
struct conf.beg label asym id: A
struct conf.beg label comp id: SER
struct conf.beg label seq id: 145
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 594
struct conf.end label asym id: A
struct conf.end label comp id: GLN
struct conf.end label seq id: 160
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB2
struct conf.pdbx PDB helix length: 16

HELX P12
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P12
struct conf.beg auth asym id: A
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 605
struct conf.beg label asym id: A
struct conf.beg label comp id: SER
struct conf.beg label seq id: 171
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: THR
struct conf.end auth seq id: 623
struct conf.end label asym id: A
struct conf.end label comp id: THR
struct conf.end label seq id: 189
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB3
struct conf.pdbx PDB helix length: 19

HELX P13
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P13
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 624
struct conf.beg label asym id: A
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 190
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: THR
struct conf.end auth seq id: 641
struct conf.end label asym id: A
struct conf.end label comp id: THR
struct conf.end label seq id: 207
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB4
struct conf.pdbx PDB helix length: 18

HELX P14
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P14
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ASN
struct conf.beg auth seq id: 648
struct conf.beg label asym id: A
struct conf.beg label comp id: ASN
struct conf.beg label seq id: 214
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 665
struct conf.end label asym id: A
struct conf.end label comp id: LEU
struct conf.end label seq id: 231
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB5
struct conf.pdbx PDB helix length: 18

HELX P15
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P15
struct conf.beg auth asym id: A
struct conf.beg auth comp id: CYS
struct conf.beg auth seq id: 666
struct conf.beg label asym id: A
struct conf.beg label comp id: CYS
struct conf.beg label seq id: 232
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LYS
struct conf.end auth seq id: 670
struct conf.end label asym id: A
struct conf.end label comp id: LYS
struct conf.end label seq id: 236
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AB6
struct conf.pdbx PDB helix length: 5

HELX P16
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P16
struct conf.beg auth asym id: A
struct conf.beg auth comp id: LEU
struct conf.beg auth seq id: 671
struct conf.beg label asym id: A
struct conf.beg label comp id: LEU
struct conf.beg label seq id: 237
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 696
struct conf.end label asym id: A
struct conf.end label comp id: LEU
struct conf.end label seq id: 262
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB7
struct conf.pdbx PDB helix length: 26

HELX P17
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P17
struct conf.beg auth asym id: A
struct conf.beg auth comp id: ILE
struct conf.beg auth seq id: 701
struct conf.beg label asym id: A
struct conf.beg label comp id: ILE
struct conf.beg label seq id: 267
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: ASP
struct conf.end auth seq id: 710
struct conf.end label asym id: A
struct conf.end label comp id: ASP
struct conf.end label seq id: 276
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AB8
struct conf.pdbx PDB helix length: 10

HELX P18
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P18
struct conf.beg auth asym id: A
struct conf.beg auth comp id: GLU
struct conf.beg auth seq id: 711
struct conf.beg label asym id: A
struct conf.beg label comp id: GLU
struct conf.beg label seq id: 277
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: VAL
struct conf.end auth seq id: 723
struct conf.end label asym id: A
struct conf.end label comp id: VAL
struct conf.end label seq id: 289
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AB9
struct conf.pdbx PDB helix length: 13

HELX P19
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P19
struct conf.beg auth asym id: A
struct conf.beg auth comp id: VAL
struct conf.beg auth seq id: 723
struct conf.beg label asym id: A
struct conf.beg label comp id: VAL
struct conf.beg label seq id: 289
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 735
struct conf.end label asym id: A
struct conf.end label comp id: LEU
struct conf.end label seq id: 301
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AC1
struct conf.pdbx PDB helix length: 13

HELX P20
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P20
struct conf.beg auth asym id: A
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 738
struct conf.beg label asym id: A
struct conf.beg label comp id: THR
struct conf.beg label seq id: 304
struct conf.conf type id: HELX_P
struct conf.end auth asym id: A
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 758
struct conf.end label asym id: A
struct conf.end label comp id: GLY
struct conf.end label seq id: 324
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AC2
struct conf.pdbx PDB helix length: 21

HELX P21
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P21
struct conf.beg auth asym id: B
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 442
struct conf.beg label asym id: B
struct conf.beg label comp id: THR
struct conf.beg label seq id: 8
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 451
struct conf.end label asym id: B
struct conf.end label comp id: GLN
struct conf.end label seq id: 17
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AC3
struct conf.pdbx PDB helix length: 10

HELX P22
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P22
struct conf.beg auth asym id: B
struct conf.beg auth comp id: ARG
struct conf.beg auth seq id: 457
struct conf.beg label asym id: B
struct conf.beg label comp id: ARG
struct conf.beg label seq id: 23
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: ILE
struct conf.end auth seq id: 462
struct conf.end label asym id: B
struct conf.end label comp id: ILE
struct conf.end label seq id: 28
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AC4
struct conf.pdbx PDB helix length: 6

HELX P23
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P23
struct conf.beg auth asym id: B
struct conf.beg auth comp id: PHE
struct conf.beg auth seq id: 472
struct conf.beg label asym id: B
struct conf.beg label comp id: PHE
struct conf.beg label seq id: 38
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: ASN
struct conf.end auth seq id: 474
struct conf.end label asym id: B
struct conf.end label comp id: ASN
struct conf.end label seq id: 40
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AC5
struct conf.pdbx PDB helix length: 3

HELX P24
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P24
struct conf.beg auth asym id: B
struct conf.beg auth comp id: MET
struct conf.beg auth seq id: 475
struct conf.beg label asym id: B
struct conf.beg label comp id: MET
struct conf.beg label seq id: 41
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 489
struct conf.end label asym id: B
struct conf.end label comp id: GLY
struct conf.end label seq id: 55
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AC6
struct conf.pdbx PDB helix length: 15

HELX P25
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P25
struct conf.beg auth asym id: B
struct conf.beg auth comp id: GLU
struct conf.beg auth seq id: 494
struct conf.beg label asym id: B
struct conf.beg label comp id: GLU
struct conf.beg label seq id: 60
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: ASN
struct conf.end auth seq id: 508
struct conf.end label asym id: B
struct conf.end label comp id: ASN
struct conf.end label seq id: 74
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AC7
struct conf.pdbx PDB helix length: 15

HELX P26
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P26
struct conf.beg auth asym id: B
struct conf.beg auth comp id: ASN
struct conf.beg auth seq id: 516
struct conf.beg label asym id: B
struct conf.beg label comp id: ASN
struct conf.beg label seq id: 82
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: ASN
struct conf.end auth seq id: 534
struct conf.end label asym id: B
struct conf.end label comp id: ASN
struct conf.end label seq id: 100
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AC8
struct conf.pdbx PDB helix length: 19

HELX P27
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P27
struct conf.beg auth asym id: B
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 539
struct conf.beg label asym id: B
struct conf.beg label comp id: THR
struct conf.beg label seq id: 105
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: HIS
struct conf.end auth seq id: 553
struct conf.end label asym id: B
struct conf.end label comp id: HIS
struct conf.end label seq id: 119
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AC9
struct conf.pdbx PDB helix length: 15

HELX P28
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P28
struct conf.beg auth asym id: B
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 561
struct conf.beg label asym id: B
struct conf.beg label comp id: SER
struct conf.beg label seq id: 127
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: PHE
struct conf.end auth seq id: 568
struct conf.end label asym id: B
struct conf.end label comp id: PHE
struct conf.end label seq id: 134
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AD1
struct conf.pdbx PDB helix length: 8

HELX P29
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P29
struct conf.beg auth asym id: B
struct conf.beg auth comp id: HIS
struct conf.beg auth seq id: 570
struct conf.beg label asym id: B
struct conf.beg label comp id: HIS
struct conf.beg label seq id: 136
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: TYR
struct conf.end auth seq id: 576
struct conf.end label asym id: B
struct conf.end label comp id: TYR
struct conf.end label seq id: 142
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AD2
struct conf.pdbx PDB helix length: 7

HELX P30
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P30
struct conf.beg auth asym id: B
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 579
struct conf.beg label asym id: B
struct conf.beg label comp id: SER
struct conf.beg label seq id: 145
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: GLN
struct conf.end auth seq id: 594
struct conf.end label asym id: B
struct conf.end label comp id: GLN
struct conf.end label seq id: 160
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AD3
struct conf.pdbx PDB helix length: 16

HELX P31
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P31
struct conf.beg auth asym id: B
struct conf.beg auth comp id: SER
struct conf.beg auth seq id: 605
struct conf.beg label asym id: B
struct conf.beg label comp id: SER
struct conf.beg label seq id: 171
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: ALA
struct conf.end auth seq id: 622
struct conf.end label asym id: B
struct conf.end label comp id: ALA
struct conf.end label seq id: 188
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AD4
struct conf.pdbx PDB helix length: 18

HELX P32
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P32
struct conf.beg auth asym id: B
struct conf.beg auth comp id: ASP
struct conf.beg auth seq id: 624
struct conf.beg label asym id: B
struct conf.beg label comp id: ASP
struct conf.beg label seq id: 190
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: THR
struct conf.end auth seq id: 641
struct conf.end label asym id: B
struct conf.end label comp id: THR
struct conf.end label seq id: 207
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AD5
struct conf.pdbx PDB helix length: 18

HELX P33
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P33
struct conf.beg auth asym id: B
struct conf.beg auth comp id: ASN
struct conf.beg auth seq id: 648
struct conf.beg label asym id: B
struct conf.beg label comp id: ASN
struct conf.beg label seq id: 214
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 665
struct conf.end label asym id: B
struct conf.end label comp id: LEU
struct conf.end label seq id: 231
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AD6
struct conf.pdbx PDB helix length: 18

HELX P34
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P34
struct conf.beg auth asym id: B
struct conf.beg auth comp id: CYS
struct conf.beg auth seq id: 666
struct conf.beg label asym id: B
struct conf.beg label comp id: CYS
struct conf.beg label seq id: 232
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: LYS
struct conf.end auth seq id: 670
struct conf.end label asym id: B
struct conf.end label comp id: LYS
struct conf.end label seq id: 236
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AD7
struct conf.pdbx PDB helix length: 5

HELX P35
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P35
struct conf.beg auth asym id: B
struct conf.beg auth comp id: LEU
struct conf.beg auth seq id: 671
struct conf.beg label asym id: B
struct conf.beg label comp id: LEU
struct conf.beg label seq id: 237
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: LYS
struct conf.end auth seq id: 695
struct conf.end label asym id: B
struct conf.end label comp id: LYS
struct conf.end label seq id: 261
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AD8
struct conf.pdbx PDB helix length: 25

HELX P36
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P36
struct conf.beg auth asym id: B
struct conf.beg auth comp id: ILE
struct conf.beg auth seq id: 701
struct conf.beg label asym id: B
struct conf.beg label comp id: ILE
struct conf.beg label seq id: 267
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: ASP
struct conf.end auth seq id: 710
struct conf.end label asym id: B
struct conf.end label comp id: ASP
struct conf.end label seq id: 276
struct conf.pdbx PDB helix class: 5
struct conf.pdbx PDB helix id: AD9
struct conf.pdbx PDB helix length: 10

HELX P37
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P37
struct conf.beg auth asym id: B
struct conf.beg auth comp id: GLU
struct conf.beg auth seq id: 711
struct conf.beg label asym id: B
struct conf.beg label comp id: GLU
struct conf.beg label seq id: 277
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: VAL
struct conf.end auth seq id: 723
struct conf.end label asym id: B
struct conf.end label comp id: VAL
struct conf.end label seq id: 289
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AE1
struct conf.pdbx PDB helix length: 13

HELX P38
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P38
struct conf.beg auth asym id: B
struct conf.beg auth comp id: VAL
struct conf.beg auth seq id: 723
struct conf.beg label asym id: B
struct conf.beg label comp id: VAL
struct conf.beg label seq id: 289
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: LEU
struct conf.end auth seq id: 735
struct conf.end label asym id: B
struct conf.end label comp id: LEU
struct conf.end label seq id: 301
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AE2
struct conf.pdbx PDB helix length: 13

HELX P39
type: struct conf
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conf type: HELX P
struct conf.id: HELX_P39
struct conf.beg auth asym id: B
struct conf.beg auth comp id: THR
struct conf.beg auth seq id: 738
struct conf.beg label asym id: B
struct conf.beg label comp id: THR
struct conf.beg label seq id: 304
struct conf.conf type id: HELX_P
struct conf.end auth asym id: B
struct conf.end auth comp id: GLY
struct conf.end auth seq id: 758
struct conf.end label asym id: B
struct conf.end label comp id: GLY
struct conf.end label seq id: 324
struct conf.pdbx PDB helix class: 1
struct conf.pdbx PDB helix id: AE3
struct conf.pdbx PDB helix length: 21

disulf1
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: disulf
struct conn.id: disulf1
struct conn.conn type id: disulf
struct conn.pdbx dist value: 2.043
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: CYS
struct conn.ptnr1 auth seq id: 488
struct conn.ptnr1 label asym id: A
struct conn.ptnr1 label atom id: SG
struct conn.ptnr1 label comp id: CYS
struct conn.ptnr1 label seq id: 54
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: CYS
struct conn.ptnr2 auth seq id: 492
struct conn.ptnr2 label asym id: A
struct conn.ptnr2 label atom id: SG
struct conn.ptnr2 label comp id: CYS
struct conn.ptnr2 label seq id: 58
struct conn.ptnr2 symmetry: 1_555

disulf
referenced by struct conn: disulf1
type: struct conn type
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
struct conn type.id: disulf

metalc1
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc1
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.139
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: HIS
struct conn.ptnr1 auth seq id: 519
struct conn.ptnr1 label asym id: A
struct conn.ptnr1 label atom id: NE2
struct conn.ptnr1 label comp id: HIS
struct conn.ptnr1 label seq id: 85
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: ZN
struct conn.ptnr2 auth seq id: 901
struct conn.ptnr2 label asym id: C
struct conn.ptnr2 label atom id: ZN
struct conn.ptnr2 label comp id: ZN
struct conn.ptnr2 symmetry: 1_555

metalc
referenced by struct conn: metalc1
referenced by struct conn: metalc2
referenced by struct conn: metalc3
referenced by struct conn: metalc4
referenced by struct conn: metalc5
referenced by struct conn: metalc6
referenced by struct conn: metalc7
referenced by struct conn: metalc8
referenced by struct conn: metalc9
referenced by struct conn: metalc10
referenced by struct conn: metalc11
referenced by struct conn: metalc12
referenced by struct conn: metalc13
referenced by struct conn: metalc14
referenced by struct conn: metalc15
referenced by struct conn: metalc16
referenced by struct conn: metalc17
referenced by struct conn: metalc18
referenced by struct conn: metalc19
referenced by struct conn: metalc20
referenced by struct conn: metalc21
referenced by struct conn: metalc22
type: struct conn type
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
struct conn type.id: metalc

metalc2
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc2
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.092
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: HIS
struct conn.ptnr1 auth seq id: 553
struct conn.ptnr1 label asym id: A
struct conn.ptnr1 label atom id: NE2
struct conn.ptnr1 label comp id: HIS
struct conn.ptnr1 label seq id: 119
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: ZN
struct conn.ptnr2 auth seq id: 901
struct conn.ptnr2 label asym id: C
struct conn.ptnr2 label atom id: ZN
struct conn.ptnr2 label comp id: ZN
struct conn.ptnr2 symmetry: 1_555

metalc3
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc3
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.094
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: ASP
struct conn.ptnr1 auth seq id: 554
struct conn.ptnr1 label asym id: A
struct conn.ptnr1 label atom id: OD2
struct conn.ptnr1 label comp id: ASP
struct conn.ptnr1 label seq id: 120
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: ZN
struct conn.ptnr2 auth seq id: 901
struct conn.ptnr2 label asym id: C
struct conn.ptnr2 label atom id: ZN
struct conn.ptnr2 label comp id: ZN
struct conn.ptnr2 symmetry: 1_555

metalc4
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc4
struct conn.conn type id: metalc
struct conn.pdbx dist value: 1.904
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: ASP
struct conn.ptnr1 auth seq id: 554
struct conn.ptnr1 label asym id: A
struct conn.ptnr1 label atom id: OD1
struct conn.ptnr1 label comp id: ASP
struct conn.ptnr1 label seq id: 120
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: MG
struct conn.ptnr2 auth seq id: 902
struct conn.ptnr2 label asym id: D
struct conn.ptnr2 label atom id: MG
struct conn.ptnr2 label comp id: MG
struct conn.ptnr2 symmetry: 1_555

metalc5
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc5
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.120
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: ASP
struct conn.ptnr1 auth seq id: 664
struct conn.ptnr1 label asym id: A
struct conn.ptnr1 label atom id: OD1
struct conn.ptnr1 label comp id: ASP
struct conn.ptnr1 label seq id: 230
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: ZN
struct conn.ptnr2 auth seq id: 901
struct conn.ptnr2 label asym id: C
struct conn.ptnr2 label atom id: ZN
struct conn.ptnr2 label comp id: ZN
struct conn.ptnr2 symmetry: 1_555

metalc6
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc6
struct conn.conn type id: metalc
struct conn.pdbx dist value: 1.909
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: ZN
struct conn.ptnr1 auth seq id: 901
struct conn.ptnr1 label asym id: C
struct conn.ptnr1 label atom id: ZN
struct conn.ptnr1 label comp id: ZN
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 1003
struct conn.ptnr2 label asym id: I
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

metalc7
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc7
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.055
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: MG
struct conn.ptnr1 auth seq id: 902
struct conn.ptnr1 label asym id: D
struct conn.ptnr1 label atom id: MG
struct conn.ptnr1 label comp id: MG
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 1003
struct conn.ptnr2 label asym id: I
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

metalc8
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc8
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.365
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: MG
struct conn.ptnr1 auth seq id: 902
struct conn.ptnr1 label asym id: D
struct conn.ptnr1 label atom id: MG
struct conn.ptnr1 label comp id: MG
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 1011
struct conn.ptnr2 label asym id: I
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

metalc9
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc9
struct conn.conn type id: metalc
struct conn.pdbx dist value: 1.938
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: MG
struct conn.ptnr1 auth seq id: 902
struct conn.ptnr1 label asym id: D
struct conn.ptnr1 label atom id: MG
struct conn.ptnr1 label comp id: MG
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 1013
struct conn.ptnr2 label asym id: I
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

metalc10
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc10
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.069
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: MG
struct conn.ptnr1 auth seq id: 902
struct conn.ptnr1 label asym id: D
struct conn.ptnr1 label atom id: MG
struct conn.ptnr1 label comp id: MG
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 1027
struct conn.ptnr2 label asym id: I
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

metalc11
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc11
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.019
struct conn.ptnr1 auth asym id: A
struct conn.ptnr1 auth comp id: MG
struct conn.ptnr1 auth seq id: 902
struct conn.ptnr1 label asym id: D
struct conn.ptnr1 label atom id: MG
struct conn.ptnr1 label comp id: MG
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: A
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 1046
struct conn.ptnr2 label asym id: I
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

metalc12
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc12
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.161
struct conn.ptnr1 auth asym id: B
struct conn.ptnr1 auth comp id: HIS
struct conn.ptnr1 auth seq id: 519
struct conn.ptnr1 label asym id: B
struct conn.ptnr1 label atom id: NE2
struct conn.ptnr1 label comp id: HIS
struct conn.ptnr1 label seq id: 85
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: B
struct conn.ptnr2 auth comp id: ZN
struct conn.ptnr2 auth seq id: 801
struct conn.ptnr2 label asym id: F
struct conn.ptnr2 label atom id: ZN
struct conn.ptnr2 label comp id: ZN
struct conn.ptnr2 symmetry: 1_555

metalc13
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc13
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.099
struct conn.ptnr1 auth asym id: B
struct conn.ptnr1 auth comp id: HIS
struct conn.ptnr1 auth seq id: 553
struct conn.ptnr1 label asym id: B
struct conn.ptnr1 label atom id: NE2
struct conn.ptnr1 label comp id: HIS
struct conn.ptnr1 label seq id: 119
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: B
struct conn.ptnr2 auth comp id: ZN
struct conn.ptnr2 auth seq id: 801
struct conn.ptnr2 label asym id: F
struct conn.ptnr2 label atom id: ZN
struct conn.ptnr2 label comp id: ZN
struct conn.ptnr2 symmetry: 1_555

metalc14
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc14
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.173
struct conn.ptnr1 auth asym id: B
struct conn.ptnr1 auth comp id: ASP
struct conn.ptnr1 auth seq id: 554
struct conn.ptnr1 label asym id: B
struct conn.ptnr1 label atom id: OD2
struct conn.ptnr1 label comp id: ASP
struct conn.ptnr1 label seq id: 120
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: B
struct conn.ptnr2 auth comp id: ZN
struct conn.ptnr2 auth seq id: 801
struct conn.ptnr2 label asym id: F
struct conn.ptnr2 label atom id: ZN
struct conn.ptnr2 label comp id: ZN
struct conn.ptnr2 symmetry: 1_555

metalc15
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc15
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.062
struct conn.ptnr1 auth asym id: B
struct conn.ptnr1 auth comp id: ASP
struct conn.ptnr1 auth seq id: 554
struct conn.ptnr1 label asym id: B
struct conn.ptnr1 label atom id: OD1
struct conn.ptnr1 label comp id: ASP
struct conn.ptnr1 label seq id: 120
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: B
struct conn.ptnr2 auth comp id: MG
struct conn.ptnr2 auth seq id: 802
struct conn.ptnr2 label asym id: G
struct conn.ptnr2 label atom id: MG
struct conn.ptnr2 label comp id: MG
struct conn.ptnr2 symmetry: 1_555

metalc16
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc16
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.103
struct conn.ptnr1 auth asym id: B
struct conn.ptnr1 auth comp id: ASP
struct conn.ptnr1 auth seq id: 664
struct conn.ptnr1 label asym id: B
struct conn.ptnr1 label atom id: OD1
struct conn.ptnr1 label comp id: ASP
struct conn.ptnr1 label seq id: 230
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: B
struct conn.ptnr2 auth comp id: ZN
struct conn.ptnr2 auth seq id: 801
struct conn.ptnr2 label asym id: F
struct conn.ptnr2 label atom id: ZN
struct conn.ptnr2 label comp id: ZN
struct conn.ptnr2 symmetry: 1_555

metalc17
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc17
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.184
struct conn.ptnr1 auth asym id: B
struct conn.ptnr1 auth comp id: ZN
struct conn.ptnr1 auth seq id: 801
struct conn.ptnr1 label asym id: F
struct conn.ptnr1 label atom id: ZN
struct conn.ptnr1 label comp id: ZN
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: B
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 914
struct conn.ptnr2 label asym id: J
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

metalc18
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc18
struct conn.conn type id: metalc
struct conn.pdbx dist value: 1.979
struct conn.ptnr1 auth asym id: B
struct conn.ptnr1 auth comp id: MG
struct conn.ptnr1 auth seq id: 802
struct conn.ptnr1 label asym id: G
struct conn.ptnr1 label atom id: MG
struct conn.ptnr1 label comp id: MG
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: B
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 914
struct conn.ptnr2 label asym id: J
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

metalc19
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc19
struct conn.conn type id: metalc
struct conn.pdbx dist value: 1.929
struct conn.ptnr1 auth asym id: B
struct conn.ptnr1 auth comp id: MG
struct conn.ptnr1 auth seq id: 802
struct conn.ptnr1 label asym id: G
struct conn.ptnr1 label atom id: MG
struct conn.ptnr1 label comp id: MG
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: B
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 921
struct conn.ptnr2 label asym id: J
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

metalc20
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc20
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.280
struct conn.ptnr1 auth asym id: B
struct conn.ptnr1 auth comp id: MG
struct conn.ptnr1 auth seq id: 802
struct conn.ptnr1 label asym id: G
struct conn.ptnr1 label atom id: MG
struct conn.ptnr1 label comp id: MG
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: B
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 922
struct conn.ptnr2 label asym id: J
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

metalc21
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc21
struct conn.conn type id: metalc
struct conn.pdbx dist value: 2.173
struct conn.ptnr1 auth asym id: B
struct conn.ptnr1 auth comp id: MG
struct conn.ptnr1 auth seq id: 802
struct conn.ptnr1 label asym id: G
struct conn.ptnr1 label atom id: MG
struct conn.ptnr1 label comp id: MG
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: B
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 924
struct conn.ptnr2 label asym id: J
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

metalc22
type: struct conn
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct conn type: metalc
struct conn.id: metalc22
struct conn.conn type id: metalc
struct conn.pdbx dist value: 1.887
struct conn.ptnr1 auth asym id: B
struct conn.ptnr1 auth comp id: MG
struct conn.ptnr1 auth seq id: 802
struct conn.ptnr1 label asym id: G
struct conn.ptnr1 label atom id: MG
struct conn.ptnr1 label comp id: MG
struct conn.ptnr1 symmetry: 1_555
struct conn.ptnr2 auth asym id: B
struct conn.ptnr2 auth comp id: HOH
struct conn.ptnr2 auth seq id: 930
struct conn.ptnr2 label asym id: J
struct conn.ptnr2 label atom id: O
struct conn.ptnr2 label comp id: HOH
struct conn.ptnr2 symmetry: 1_555

8DI4
type: struct keywords
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entry: entry
struct keywords.entry id: 8DI4
struct keywords.pdbx keywords: HYDROLASE/HYDROLASE INHIBITOR
struct keywords.text: PDE10A, HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex

http://rdf.wwpdb.org/pdb/8DI4/struct_ref/1
type: struct ref
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entity: http://rdf.wwpdb.org/pdb/8DI4/entity/1
struct ref.id: 1
struct ref.db code: PDE10_HUMAN
struct ref.db name: UNP
struct ref.entity id: 1
struct ref.pdbx align begin: 439
struct ref.pdbx db accession: Q9Y233
struct ref.pdbx seq one letter code: SICTSEEWQGLMQFTLPVRLCKEIELFHFDIGPFENMWPGIFVYMVHRSCGTSCFELEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNHTLFTDLERKGLLIACLCHDLDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLEIIRKAIIATDLALYFGNRKQLEEMYQTGSLNLNNQSHRDRVIGLMMTACDLCSVTKLWPVTKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKKDEVPQGQLGFYNAVAIPCYTTLTQILPPTEPLLKACRDNLSQWEKVIRGEETATWISSPSVAQKAAASED
link to uniprot: uniprot:Q9Y233
referenced by struct ref seq: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/1
referenced by struct ref seq: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/2

uniprot:Q9Y233

http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/1
type: struct ref seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct ref: http://rdf.wwpdb.org/pdb/8DI4/struct_ref/1
struct ref seq.align id: 1
struct ref seq.db align beg: 439
struct ref seq.db align end: 779
struct ref seq.pdbx PDB id code: 8DI4
struct ref seq.pdbx auth seq align beg: 439
struct ref seq.pdbx auth seq align end: 779
struct ref seq.pdbx db accession: Q9Y233
struct ref seq.pdbx strand id: A
struct ref seq.ref id: 1
struct ref seq.seq align beg: 5
struct ref seq.seq align end: 345
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/1
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/2
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/3
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/4

http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/2
type: struct ref seq
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct ref: http://rdf.wwpdb.org/pdb/8DI4/struct_ref/1
struct ref seq.align id: 2
struct ref seq.db align beg: 439
struct ref seq.db align end: 779
struct ref seq.pdbx PDB id code: 8DI4
struct ref seq.pdbx auth seq align beg: 439
struct ref seq.pdbx auth seq align end: 779
struct ref seq.pdbx db accession: Q9Y233
struct ref seq.pdbx strand id: B
struct ref seq.ref id: 1
struct ref seq.seq align beg: 5
struct ref seq.seq align end: 345
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/5
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/6
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/7
referenced by struct ref seq dif: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/8

http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/1
type: struct ref seq dif
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct ref seq: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 1
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: GLY
struct ref seq dif.pdbx auth seq num: 435
struct ref seq dif.pdbx pdb id code: 8DI4
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: Q9Y233
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 1

http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/2
type: struct ref seq dif
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct ref seq: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 2
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: SER
struct ref seq dif.pdbx auth seq num: 436
struct ref seq dif.pdbx pdb id code: 8DI4
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: Q9Y233
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 2

http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/3
type: struct ref seq dif
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct ref seq: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 3
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: HIS
struct ref seq dif.pdbx auth seq num: 437
struct ref seq dif.pdbx pdb id code: 8DI4
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: Q9Y233
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 3

http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/4
type: struct ref seq dif
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct ref seq: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/1
struct ref seq dif.pdbx ordinal: 4
struct ref seq dif.align id: 1
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: MET
struct ref seq dif.pdbx auth seq num: 438
struct ref seq dif.pdbx pdb id code: 8DI4
struct ref seq dif.pdbx pdb strand id: A
struct ref seq dif.pdbx seq db accession code: Q9Y233
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 4

http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/5
type: struct ref seq dif
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct ref seq: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/2
struct ref seq dif.pdbx ordinal: 5
struct ref seq dif.align id: 2
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: GLY
struct ref seq dif.pdbx auth seq num: 435
struct ref seq dif.pdbx pdb id code: 8DI4
struct ref seq dif.pdbx pdb strand id: B
struct ref seq dif.pdbx seq db accession code: Q9Y233
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 1

http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/6
type: struct ref seq dif
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct ref seq: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/2
struct ref seq dif.pdbx ordinal: 6
struct ref seq dif.align id: 2
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: SER
struct ref seq dif.pdbx auth seq num: 436
struct ref seq dif.pdbx pdb id code: 8DI4
struct ref seq dif.pdbx pdb strand id: B
struct ref seq dif.pdbx seq db accession code: Q9Y233
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 2

http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/7
type: struct ref seq dif
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct ref seq: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/2
struct ref seq dif.pdbx ordinal: 7
struct ref seq dif.align id: 2
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: HIS
struct ref seq dif.pdbx auth seq num: 437
struct ref seq dif.pdbx pdb id code: 8DI4
struct ref seq dif.pdbx pdb strand id: B
struct ref seq dif.pdbx seq db accession code: Q9Y233
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 3

http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq_dif/8
type: struct ref seq dif
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct ref seq: http://rdf.wwpdb.org/pdb/8DI4/struct_ref_seq/2
struct ref seq dif.pdbx ordinal: 8
struct ref seq dif.align id: 2
struct ref seq dif.details: expression tag
struct ref seq dif.mon id: MET
struct ref seq dif.pdbx auth seq num: 438
struct ref seq dif.pdbx pdb id code: 8DI4
struct ref seq dif.pdbx pdb strand id: B
struct ref seq dif.pdbx seq db accession code: Q9Y233
struct ref seq dif.pdbx seq db name: UNP
struct ref seq dif.seq num: 4

8DI4
type: symmetry
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to entry: entry
symmetry.entry id: 8DI4
symmetry.int tables number: 19
symmetry.space group name H-M: P 21 21 21

A,1,1,2,Q9Y233
type: pdbx sifts unp segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts unp segments.entity id: 1
pdbx sifts unp segments.asym id: A
pdbx sifts unp segments.unp acc: Q9Y233
pdbx sifts unp segments.segment id: 2
pdbx sifts unp segments.instance id: 1
link to uniprot: uniprot:Q9Y233
pdbx sifts unp segments.unp start: 439
pdbx sifts unp segments.unp end: 779
pdbx sifts unp segments.seq id start: 5
pdbx sifts unp segments.seq id end: 345
pdbx sifts unp segments.best mapping: Y
pdbx sifts unp segments.identity: 1.000

B,1,1,2,Q9Y233
type: pdbx sifts unp segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts unp segments.entity id: 1
pdbx sifts unp segments.asym id: B
pdbx sifts unp segments.unp acc: Q9Y233
pdbx sifts unp segments.segment id: 2
pdbx sifts unp segments.instance id: 1
link to uniprot: uniprot:Q9Y233
pdbx sifts unp segments.unp start: 439
pdbx sifts unp segments.unp end: 779
pdbx sifts unp segments.seq id start: 5
pdbx sifts unp segments.seq id end: 345
pdbx sifts unp segments.best mapping: Y
pdbx sifts unp segments.identity: 1.000

A,1,1,1,4,2,InterPro,IPR036971
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR036971
pdbx sifts xref db segments.segment id: 1
pdbx sifts xref db segments.instance id: 1
pdbx sifts xref db segments.seq id start: 2
pdbx sifts xref db segments.seq id end: 4
link to interpro: interpro:IPR036971

interpro:IPR036971

A,1,1,2,332,5,InterPro,IPR036971
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR036971
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 1
pdbx sifts xref db segments.seq id start: 5
pdbx sifts xref db segments.seq id end: 332
link to interpro: interpro:IPR036971

A,1,2,2,134,119,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 2
pdbx sifts xref db segments.seq id start: 119
pdbx sifts xref db segments.seq id end: 134
link to interpro: interpro:IPR023088

interpro:IPR023088

A,1,3,2,118,105,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 3
pdbx sifts xref db segments.seq id start: 105
pdbx sifts xref db segments.seq id end: 118
link to interpro: interpro:IPR023088

A,1,4,2,239,226,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 4
pdbx sifts xref db segments.seq id start: 226
pdbx sifts xref db segments.seq id end: 239
link to interpro: interpro:IPR023088

A,1,5,2,161,145,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 5
pdbx sifts xref db segments.seq id start: 145
pdbx sifts xref db segments.seq id end: 161
link to interpro: interpro:IPR023088

A,1,6,2,325,8,InterPro,IPR002073
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR002073
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 6
pdbx sifts xref db segments.seq id start: 8
pdbx sifts xref db segments.seq id end: 325
link to interpro: interpro:IPR002073

interpro:IPR002073

A,1,7,2,244,78,InterPro,IPR003607
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR003607
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 7
pdbx sifts xref db segments.seq id start: 78
pdbx sifts xref db segments.seq id end: 244
link to interpro: interpro:IPR003607

interpro:IPR003607

A,1,8,2,253,80,InterPro,IPR003607
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR003607
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 8
pdbx sifts xref db segments.seq id start: 80
pdbx sifts xref db segments.seq id end: 253
link to interpro: interpro:IPR003607

A,1,9,2,253,80,InterPro,IPR003607
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR003607
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 9
pdbx sifts xref db segments.seq id start: 80
pdbx sifts xref db segments.seq id end: 253
link to interpro: interpro:IPR003607

A,1,10,2,311,80,InterPro,IPR002073
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR002073
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 10
pdbx sifts xref db segments.seq id start: 80
pdbx sifts xref db segments.seq id end: 311
link to interpro: interpro:IPR002073

A,1,11,2,130,119,InterPro,IPR023174
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023174
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 11
pdbx sifts xref db segments.seq id start: 119
pdbx sifts xref db segments.seq id end: 130
link to interpro: interpro:IPR023174

interpro:IPR023174

A,1,12,2,89,76,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 12
pdbx sifts xref db segments.seq id start: 76
pdbx sifts xref db segments.seq id end: 89
link to interpro: interpro:IPR023088

A,1,13,2,259,243,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 13
pdbx sifts xref db segments.seq id start: 243
pdbx sifts xref db segments.seq id end: 259
link to interpro: interpro:IPR023088

A,1,14,2,324,5,SCOP2B,8101757
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: SCOP2B
pdbx sifts xref db segments.xref db acc: 8101757
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 14
pdbx sifts xref db segments.seq id start: 5
pdbx sifts xref db segments.seq id end: 324
link to scop: scop2:8101757

A,1,15,2,311,80,Pfam,PF00233
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: A
pdbx sifts xref db segments.xref db: Pfam
pdbx sifts xref db segments.xref db acc: PF00233
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 15
pdbx sifts xref db segments.seq id start: 80
pdbx sifts xref db segments.seq id end: 311
link to pfam: pfam:PF00233

pfam:PF00233

B,1,1,1,4,2,InterPro,IPR036971
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR036971
pdbx sifts xref db segments.segment id: 1
pdbx sifts xref db segments.instance id: 1
pdbx sifts xref db segments.seq id start: 2
pdbx sifts xref db segments.seq id end: 4
link to interpro: interpro:IPR036971

B,1,1,2,130,119,InterPro,IPR023174
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023174
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 1
pdbx sifts xref db segments.seq id start: 119
pdbx sifts xref db segments.seq id end: 130
link to interpro: interpro:IPR023174

B,1,2,2,311,80,InterPro,IPR002073
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR002073
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 2
pdbx sifts xref db segments.seq id start: 80
pdbx sifts xref db segments.seq id end: 311
link to interpro: interpro:IPR002073

B,1,3,2,244,78,InterPro,IPR003607
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR003607
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 3
pdbx sifts xref db segments.seq id start: 78
pdbx sifts xref db segments.seq id end: 244
link to interpro: interpro:IPR003607

B,1,4,2,134,119,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 4
pdbx sifts xref db segments.seq id start: 119
pdbx sifts xref db segments.seq id end: 134
link to interpro: interpro:IPR023088

B,1,5,2,161,145,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 5
pdbx sifts xref db segments.seq id start: 145
pdbx sifts xref db segments.seq id end: 161
link to interpro: interpro:IPR023088

B,1,6,2,118,105,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 6
pdbx sifts xref db segments.seq id start: 105
pdbx sifts xref db segments.seq id end: 118
link to interpro: interpro:IPR023088

B,1,7,2,253,80,InterPro,IPR003607
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR003607
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 7
pdbx sifts xref db segments.seq id start: 80
pdbx sifts xref db segments.seq id end: 253
link to interpro: interpro:IPR003607

B,1,8,2,253,80,InterPro,IPR003607
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR003607
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 8
pdbx sifts xref db segments.seq id start: 80
pdbx sifts xref db segments.seq id end: 253
link to interpro: interpro:IPR003607

B,1,9,2,332,5,InterPro,IPR036971
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR036971
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 9
pdbx sifts xref db segments.seq id start: 5
pdbx sifts xref db segments.seq id end: 332
link to interpro: interpro:IPR036971

B,1,10,2,325,8,InterPro,IPR002073
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR002073
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 10
pdbx sifts xref db segments.seq id start: 8
pdbx sifts xref db segments.seq id end: 325
link to interpro: interpro:IPR002073

B,1,11,2,89,76,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 11
pdbx sifts xref db segments.seq id start: 76
pdbx sifts xref db segments.seq id end: 89
link to interpro: interpro:IPR023088

B,1,12,2,259,243,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 12
pdbx sifts xref db segments.seq id start: 243
pdbx sifts xref db segments.seq id end: 259
link to interpro: interpro:IPR023088

B,1,13,2,239,226,InterPro,IPR023088
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: InterPro
pdbx sifts xref db segments.xref db acc: IPR023088
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 13
pdbx sifts xref db segments.seq id start: 226
pdbx sifts xref db segments.seq id end: 239
link to interpro: interpro:IPR023088

B,1,14,2,324,5,SCOP2B,8101757
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: SCOP2B
pdbx sifts xref db segments.xref db acc: 8101757
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 14
pdbx sifts xref db segments.seq id start: 5
pdbx sifts xref db segments.seq id end: 324
link to scop: scop2:8101757

B,1,15,2,311,80,Pfam,PF00233
type: pdbx sifts xref db segments
of datablock: Discovery of MK-8189, a highly potent and selective PDE10A inhibitor for the treatment of schizophrenia
reference to struct asym: struct asym
pdbx sifts xref db segments.entity id: 1
pdbx sifts xref db segments.asym id: B
pdbx sifts xref db segments.xref db: Pfam
pdbx sifts xref db segments.xref db acc: PF00233
pdbx sifts xref db segments.segment id: 2
pdbx sifts xref db segments.instance id: 15
pdbx sifts xref db segments.seq id start: 80
pdbx sifts xref db segments.seq id end: 311
link to pfam: pfam:PF00233