Wild-type Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with fragment 820, NADPH, dUMP

NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Discovery of new non-pyrimidine scaffolds as Plasmodium falciparum DHFR inhibitors by fragment-based screening.

Bifunctional dihydrofolate reductase-thymidylate synthase

National Center for Genetic Engineering and Biotechnology (Thailand)

Hydrogens have been added in their riding positions

Anti-folate, anti-malarial, plasmodium falciparum, dihydrofolate reductase, fragment, ANTIBIOTIC, OXIDOREDUCTASE