Crystal structure of NADH bound holo form of alpha-glucuronidase (TM0752) from Thermotoga maritima at 1.97 Angstrom resolution

1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE

Structural basis of catalysis and substrate recognition by the NAD(H)-dependent alpha-d-glucuronidase from the glycoside hydrolase family 4.

Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

14 % PEG 3350, 0.2 M trilithium citrate, 0.1 M imidazole with pH 5.8, 2-propanol, 7 mM NADH, 7 mM DTT

Glycosyl hydrolase family 4, NAD(P)-binding Rossmann-fold domain, LDH C-terminal domain-like, hydrolase activity, alpha-glucuronidase, HYDROLASE