Crystal Structure of a Carbonyl Reductase from Candida Parapsilosis with anti-Prelog Stereo-specificity

Crystal structure of a carbonyl reductase from Candida parapsilosis with anti-Prelog stereospecificity.

Oligomeric interactions maintain active-site structure in a noncooperative enzyme family.

buffer: 18%(w/v) PEG2K MME, 8%(v/v) isopropanol, pH 8.5, droplet: 20mg/ml SCR, 20mM Tris-HCl, 150mM NaCl, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 289K

National Science Foundation (NSF, China)

Ministry of Science and Technology (MoST, China)

The structure of mannitol-2-dehydrogenase from Agaricus bisporus

alcohol dehydrogenase, Candida parapsilosis, short-chain dehydrogenases/reductases (SDR), OXIDOREDUCTASE