Crystal structure of Sec4 in complex with Rab-GDI

A structural model of the GDP dissociation inhibitor rab membrane extraction mechanism.

Rab GDI, Secretory pathway GDP dissociation inhibitor, yeast Rab-GDI

Suppressor of RHO3 protein 6, small GTPase Sec4

12% PEG MME 2000, pH 5.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K

Rab GDP-dissociation inhibitor, Ras-related protein SEC4

Rab GTPase, prenylation, vesicular transport, Cytoplasm, Cytoplasmic vesicle, Exocytosis, GTP-binding, Lipoprotein, Membrane, Nucleotide-binding, Palmitate, Phosphoprotein, Protein transport, GTPase activation