Crystal structure of H-2Db in complex with chimeric gp100

Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.

H-2 class I histocompatibility antigen, D-B alpha chain

1.8M ammonium sulfate, 0.1M Tris Cl, pH 9.0, VAPOR DIFFUSION, HANGING DROP, temperature 277K

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, nonameric peptide chimeric gp100

MHC, H-2Db, Glycoprotein, Immune response, Membrane, MHC I, Transmembrane, Immunoglobulin domain, Secreted, Disease mutation, Melanin biosynthesis, IMMUNE SYSTEM