Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with quercetin

Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay

(3R)-hydroxymyristoyl-acyl carrier protein dehydratase

0.1M Sodium Acetate trihydrate, 2.0M Sodium Formate Additive, 20%(w/v) Benzamidine HCl, pH 3.8, VAPOR DIFFUSION, HANGING DROP, temperature 277K

(3R)-hydroxymyristoyl-acyl carrier protein dehydratase (E.C.4.2.1.-)

FabZ complex, quercetin, Cytoplasm, Lipid A biosynthesis, Lipid synthesis, Lyase