Crystal structure of full-length Thermus thermophilus CarH bound to adenosylcobalamin (dark state)

Structural basis for gene regulation by a B12-dependent photoreceptor.

Light-dependent transcriptional regulator CarH

Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)

20% PEG 3350, 0.1 M ammonium citrate tribasic pH 7

National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

two starting models were used for MR. One model contained residues 80-270 of CarH, determined by Co-SAD.

Transcription factor, light sensor, adenosylcobalamin-binding, DNA-binding, TRANSCRIPTIONAL REGULATOR