Crystal structure of Staphylococcus aureus ketol-acid reductoisomerase with hydroxyoxamate inhibitor 1

[cyclopentyl(hydroxy)amino](oxo)acetic acid

NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

Design, synthesis, in vitro activity and crystallisation of novel N-isopropyl-N-hydroxyoxamate derivatives as ketol-acid reductosiomerase (KARI) inhibitor

KARI,Acetohydroxy-acid isomeroreductase,AHIR,Alpha-keto-beta-hydroxylacyl reductoisomerase,Ketol-acid reductoisomerase type 1,Ketol-acid reductoisomerase type I

Staphylococcus aureus (strain bovine RF122 / ET3-1)

National Health and Medical Research Council (NHMRC, Australia)

Ketol-acid reductoisomerase (NADP(+)) (E.C.1.1.1.86)

ketol-acid reductoisomerase, isomerase, inhibitor, OXIDOREDUCTASE