Pim-1 Kinase Domain in Complex with 3-aminophenyl-7-azaindole

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

Proto-oncogene serine/threonine-protein kinase Pim-1

NA ACETATE, IMIDAZOLE, PH 6.5, VAPOR DIFFUSION, SITTING DROP, temperature 277K

B-Raf Kinase V600E Oncogenic Mutant in Complex with PLX3203

Proto-oncogene serine/threonine-protein kinase Pim-1 (E.C.2.7.11.1)

PIM-1, PROTO-ONCOGENE, SERINE/THREONINE KINASE, Alternative initiation, ATP-binding, Cytoplasm, Manganese, Membrane, Metal-binding, Nucleotide-binding, Nucleus, Phosphoprotein, Serine/threonine-protein kinase, Transferase