Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein

Israel Structural Proteomics Center (ISPC)

Crystallographic and biochemical studies revealing the structural basis for antizyme inhibitor function.

AZI, Ornithine decarboxylase antizyme inhibitor

0.2M CaCl2, 0.1M Tris-HCl, 6% PEG 6000, 13mM 2,6-Dimethyl-4-heptyl-beta-D-maltoside, pH 8.0, MICROBATCH UNDER OIL, temperature 292K

Crystal structure of mouse ornithine decarboxylase

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

AUTHORS STATE THAT THIS PROTEIN IS A MONOMER IN SOLUTION.

TIM-like a/b barrel domain and a sheet domain, Structural Genomics, Israel Structural Proteomics Center, ISPC, Polyamine biosynthesis, BIOSYNTHETIC PROTEIN