Mechanistic insights explain the transforming potential of the T507K substitution in the protein-tyrosine phosphatase SHP2.

1.00 degrees, 11.0 sec, detector distance 327.42 mm

Tyrosine-protein phosphatase non-receptor type 11

Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,Shp2,SH-PTP3

Escherichia coli 'BL21-Gold(DE3)pLysS AG'

National Institutes of Health/National Cancer Institute (NIH/NCI)

Tyrosine-protein phosphatase non-receptor type 11 (E.C.3.1.3.48)

Phosphatase, SHP2, PTPN11, T507K, HYDROLASE