HUMAN PI3KDELTA IN COMPLEX WITH COMPOUND 13

Application of an "inhalation by design" approach to the identification and in-vitro evaluation of novel purine based PI3K delta inhibitors.

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

Phosphatidylinositol 3-kinase regulatory subunit alpha

PI3-kinase subunit delta,PI3K-delta,PI3Kdelta,PtdIns-3-kinase subunit delta,Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,PtdIns-3-kinase subunit p110-delta,p110delta

PI3-kinase regulatory subunit alpha,PI3K regulatory subunit alpha,PtdIns-3-kinase regulatory subunit alpha,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,PI3-kinase subunit p85-alpha,PtdIns-3-kinase regulatory subunit p85-alpha

U VALUES : WITH TLS ADDED HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS

PI3KDELTA KINASE, PI3KDELTA KINASE INHIBITOR, TRANSFERASE