Crystal Structure of human NAMPT in complex with NVP-LOQ594

Identification and structure based design of cellularly active cyclo-propyl carboxamide Nicotinamide phosphoribosyltransferase (NAMPT) inhibitors

Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin

100 mM Tris/HCl pH 8.0, 23 % (w/v) PEG 3350, 200 mM NaCl

6atb contains the same protein complexed with NVP-LOD812

6azj contains the same protein complexed with NVP-LQN520

Human NAMPT runs with an apparent molecular weight corresponding to a homodimeric assembly.

Nicotinamide phosphoribosyltransferase (E.C.2.4.2.12)