Structure of the thermostabilized EAAT1 cryst mutant in complex with rubidium and barium and the allosteric inhibitor UCPH101

The ion-coupling mechanism of human excitatory amino acid transporters.

Rubidium, Barium and UCPH101 bound,Rubidium, Barium and UCPH101 bound,Rubidium, Barium and UCPH101 bound
Excitatory amino acid transporter 1,Neutral amino acid transporter B(0),Excitatory amino acid transporter 1

Sodium-dependent glutamate/aspartate transporter 1,GLAST-1,Solute carrier family 1 member 3,ATB(0),Baboon M7 virus receptor,RD114/simian type D retrovirus receptor,Sodium-dependent neutral amino acid transporter type 2,Solute carrier family 1 member 5,Sodium-dependent glutamate/aspartate transporter 1,GLAST-1,Solute carrier family 1 member 3

30% PEG400, 100 mM Tris pH 8.2, 50 mM Calcium chloride, 50 mM Barium chloride

excitatory amino acid transporter 1, human glutamate transporter, SLC1A3, ion-coupling mechanism, MEMBRANE PROTEIN