pVHL:EloB:EloC complex, in complex with capped Hydroxyproline

Dissecting Fragment-Based Lead Discovery at the Von Hippel-Lindau Protein:Hypoxia Inducible Factor 1Alpha Protein-Protein Interface.

TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2

EXTRA M AT N-TERMINUS AS RESULT OF CLONING
TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1

VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR

ELONGIN 18 KDA SUBUNIT, ELONGIN-B, ELOB, RNA POLYMERASE II TRANSCRIPTION FACTOR SIII SUBUNIT B, SIII P18

ELONGIN 15 KDA SUBUNIT, ELONGIN-C, ELOC, RNA POLYMERASE II TRANSCRIPTION FACTOR SIII SUBUNIT C, SIII P15

0.1 M NA CACODYLATE PH 6.0, 0.2 M MG ACETATE, 15% PEG3350, 5 MM DTT

STRUCTURE OF A HIF-1A-PVHL-ELONGINB-ELONGINC COMPLEX

CRYSTAL STRUCTURE OF A HYDROXYLATED HIF-1 ALPHA PEPTIDEBOUND TO THE PVHL/ELONGIN-C/ELONGIN-B COMPLEX

CRYSTAL STRUCTURE OF SOCS-2 IN COMPLEX WITH ELONGIN- B AND ELONGIN-C AT 1.9A RESOLUTION

CRYSTAL STRUCTURE OF SOCS-4 IN COMPLEX WITH ELONGIN- B AND ELONGIN-C AT 2.55A RESOLUTION

CRYSTAL STRUCTURE OF ANKYRIN REPEAT AND SOCS BOX- CONTAINING PROTEIN 9 (ASB9) IN COMPLEX WITH ELONGINB AND ELONGINC

PVHL54-213-ELOB-ELOC COMPLEX (4R)-4-HYDROXY-1-[(3- METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL )BENZYL]-L-PROLINAMIDE BOUND

PVHL54-213-ELOB-ELOC COMPLEX _ (2S,4R)-N-((1,1'- BIPHENYL)-4-YLMETHYL)-4-HYDROXY-1-(2-(3-METHYLISOXAZOL -5-YL)ACETYL)PYRROLIDINE-2-CARBOXAMIDE

PVHL54-213-ELOB-ELOC COMPLEX _ METHYL 4-(((2S,4R)- 4-HYDROXY-1-(2-(3-METHYLISOXAZOL-5-YL)ACETYL) PYRROLIDINE-2-CARBOXAMIDO)METHYL)BENZOATE

PVHL54-213-ELOB-ELOC COMPLEX_(2S,4R)-4-HYDROXY-1-( 2-(3-METHYLISOXAZOL-5-YL)ACETYL)-N-(4-NITROBENZYL) PYRROLIDINE-2-CARBOXAMIDE BOUND

VON HIPPEL-LINDAU PROTEIN-ELONGINB-ELONGINC COMPLEX, BOUND TO HIF1-ALPHA PEPTIDE

3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE (V6F): CAPPED HYDROXYPROLINE

GSH REMAINING AFTER THROMBIN CLEAVAGE
EXTRA M AT N-TERMINUS AS RESULT OF CLONING

TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR

TRANSCRIPTION, E3 UBIQUITIN LIGASE, TUMOR SUPRESSOR