Structure of P. aeruginosa PBP3 in complex with a benzoxaborole (Compound 15)

2-(5-(benzyloxy)-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-3-yl)acetic acid
2-[(3S)-1-oxidanyl-5-phenylmethoxy-3H-2,1-benzoxaborol-3-yl]ethanoic acid

High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes.

25% (w/v) polyethylene glycol 3,350, 0.1M Bis-Tris propane pH 6 and 1% (w/v) protamine sulphate

Medical Research Council (MRC, United Kingdom)

7ATM contains the same protein complexed with compound 1

7ATO contains the same protein complexed with compound 2

7ATW contains the same protein complexed with compound 3

7ATX contains the same protein complexed with compound 4

7AU0 contains the same protein complexed with compound 8

7AU1 contains the same protein complexed with compound 13

7AU8 contains the same protein complexed with compound 14

7AU9 contains the same protein complexed with compound 15

Hydrogens have been added in their riding positions

D, D-transpeptidase, boron-binding, divalency, HYDROLASE