Crystal structure of porcine heart mitochondrial complex II bound with N-Biphenyl-3-yl-2-trifluoromethyl-benzamide

Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

Succinate dehydrogenase cytochrome b560 subunit, mitochondrial

Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

Succinate-ubiquinone oxidoreductase cytochrome B large subunit, CYBL

Succinate-ubiquinone oxidoreductase cytochrome b small subunit, CybS, Succinate-ubiquinone reductase membrane anchor subunit, QPs3, CII-4, Succinate dehydrogenase complex subunit D

25mM HEPES-NAOH, 7% PEG 4000, 200mM Sucrose, 100mM NaCl, 10mM CaCl2, 0.5mM EDTA, 3% 1,6-haxanediol, 0.5% n-decyl-beta-D-maltoside, pH 7.4, VAPOR DIFFUSION, HANGING DROP, temperature 293K

the same protein complex bound with another inhibitor

the same protein complex with an empty quinone-binding pocket

THESE COMPLEX FORMS MITOCHONDRIAL RESPIRATORY COMPLEX II.
THE SEQUENCE OF CHAIN D IS REFERRED IN REF 2 IN A5GZW8, UNIPROT.

HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS U VALUES : RESIDUAL ONLY

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (E.C.1.3.5.1), Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (E.C.1.3.5.1), Succinate dehydrogenase cytochrome b560 subunit, mitochondrial, Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

respiratory complex II, inhibitors, Electron transport, Iron-sulfur, Metal-binding, Mitochondrion, Mitochondrion inner membrane, Oxidoreductase, Transit peptide, Transport, Tricarboxylic acid cycle, Heme, Transmembrane, FAD-binding protein, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex