Assignments of the 1H, 13C, and 15N, resonances of the winged helix domain of
the proto-oncoprotein c-Qin (FoxG1B)

The molecule reported in this depositon contains only the winged helix domain
(residues 131-253) of cellullar Qin. Also C 200 has been replaced by S. This
mutation has been shown to not alter the structure or DNA binding properties of
c-Qin-WHD.

Letter to the Editor: Assignments of the 1H, 13C, and 15N, resonances of the
winged helix domain of the proto-oncoprotein c-Qin (FoxG1B)

We have isolated chicken cDNA clones of the c-qin gene, the cellular counterpart
of the v-qin (Chinese for "avian") oncogene of avian sarcoma virus 31. There
are several differences between the cellular and the viral qin sequences: (i)
two nonconservative amino acid substitutions in the Qin coding region; (ii) a
truncation in the carboxyl terminus of the viral protein due to a premature
stop codon; (iii) a partial Gag sequence fused to the amino terminus of viral
Qin; and (iv) eight cell-coded amino acids which link the cellular Qin coding
domain to the viral Gag domain. We have also characterized the expression
pattern of c-qin in chicken embryos by in situ hybridization and by Northern
blot analysis. c-qin is abundantly expressed in the developing brain, and this
expression is restricted to the telencephalon of early embryos.

Chang HW, Li J, Kretzschmar D, Vogt PK.
Avian cellular homolog of the qin oncogene.
Proc Natl Acad Sci U S A. 1995 Jan 17;92(2):447-51.

Proceedings of the National Academy of Sciences of the United States of America
Avian cellular homolog of the qin oncogene.

The first 4 residues(GSHM)of the full sequence is a residual tag from cloning
and is not a part of c-qin-whd. The fifth residue G in the full sequence
corresponds to G 131 of the cellular Qin.

unnamed protein product, partial [Tetraodon nigroviridis]

HNF-3/fork head family transcription factor Qin - avian sarcoma virus 31

forkhead box protein G1 [Xenopus laevis]

forkhead box G1 [Xenopus (Silurana) tropicalis]

RecName: Full=Forkhead box protein G1; AltName: Full=Brain factor 1; Short=BF-1; Short=BF1; AltName: Full=Brain factor 2; Short

RecName: Full=Transforming protein Qin; AltName: Full=Oncogene Qin [Avian sarcoma virus 31]

RecName: Full=Forkhead box protein G1; Short=FoxG1; AltName: Full=Brain factor 1; Short=BF-1; Short=BF1; AltName: Full=Forkhead

RecName: Full=Forkhead box protein G1; Short=FoxG1 [Ceratotherium simum]

RecName: Full=Forkhead box protein G1; Short=FoxG1 [Equus burchellii]

TPA: forkhead box protein G1-like [Bos taurus]

The host-vector system used is extremely
efficient. Using Bioflow 3000 Fermenter
150 mg protein per 10 g of 13C D-Glucose was
obtained with in 8 hour period of growth.
Glucose was obtained.