Solution structure of integrin b2 monomer tranmembrane domain in bicelle

Intramembrane ionic protein-lipid interaction regulates integrin structure and function.

Cell surface adhesion glycoproteins LFA-1/CR3/p150

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0.6 mM [U-13C; U-15N] integrin b2, 20 mM Bis-Tris, 240 mM DHPC, 48 mM POPC, 24 mM POPG, 90% H2O/10% D2O

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax