Solution NMR Structure of the Coiled-coil BRCA1-PALB2 Heterodimer

Breast cancer type 1 susceptibility protein homolog (E.C.2.3.2.27), Partner and localizer of BRCA2

Antiparallel Coiled-Coil Interactions Mediate Homodimerization of the DNA Damage Repair Protein, PALB2.

The Structural Basis for Interactions Between PALB2 and BRCA1 that Mediate the Homologous Recombination DNA Damage Repair Process

RING-type E3 ubiquitin transferase BRCA1

<!DOCTYPE html PUBLIC -//W3C//DTD XHTML 1.0 Strict//EN

1.5 mM [U-100% 13C; U-100% 15N] PALB2cc, 3 mM BRCA1cc,
20 mM MES, 200 mM sodium chloride, 10 mM DTT, 5 mM CaCl2,
90% H2O/10% D2O

1.5 mM [U-100% 13C; U-100% 15N] BRCA1cc, 3 mM PALB2cc,
20 mM MES, 200 mM sodium chloride, 10 mM DTT, 5 mM CaCl2,
90% H2O/10% D2O

Zimmerman, Moseley, Kulikowski and Montelione

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax

Brunger, Adams, Clore, Gros, Nilges and Read