Backbone chemical shift assignments of the calcium-saturated human calmodulin C-domain bound to the human NaV1.2 IQ motif peptide

Structure of the C-domain Fragment of apo Calmodulin Bound to the IQ motif of Nav1.2

Solution NMR Structure of apo-calmodulin in complex with the IQ motif of Human Cardiac Sodium Channel NaV1.5

NMR, Structure of the C-domain of Calcium-saturated Calmodulin bound to the IQ motif of NaV1.2

Solution NMR Structure of apo-calmodulin bound to the IQ motif NaV1.2

NaV1.2 EFL domain allosterically enhances Ca2+ binding to sites I and II of WT and pathogenic calmodulin mutants bound to the channel CTD.

Initial methionine is residue 76 of calmodulin

voltage-gated sodium channel NaV1.2 IQ motif peptide

First four residues (GPGS) are part of a 3C protease cleavage site (numbered -4 to -1).
NaV1.2 residue 1901 is residue 5 of the peptide.

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calcium-saturated human calmodulin bound to the human NaV1.2 IQ motif peptide

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax