1H, 13C and 15N backbone assignments of the R3 domain of talin (residues 781-911) carrying four mutations T809I, T833V, T867V and T901I (R3-IVVI)

Wildtype R3 binds to vinculin and RIAM and is involved in cell adhesion

Pressure-Dependent Chemical Shifts in the R3 Domain of Talin Show that It Is Thermodynamically Poised for Binding to Either Vinculin or RIAM.

The following mutations are present in this construct: T809I, T833V, T867V and T901I
Residues 1-6 (781-786) represent a non-native affinity tag

Solution structure of the talin Vbs2b domain