Structure of constitutively monomeric CXCL12 in complex with the CXCR4 N-terminus

Structure-Based Identification of Novel Ligands Targeting Multiple Sites within a Chemokine-G-Protein-Coupled-Receptor Interface.

The N-terminal GM dipeptide is a cloning artifact.

The N-terminal GS dipeptide is a cloning artifact.

3D F1-13C filtered/F3-13C edited NOESY aliphatic

Equipped with a 1H/13C/15N TXI Cryoprobe.

torsion angle dynamics, molecular dynamics

Schwieters, Kuszewski, Tjandra and Clore

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax