Dual-phosphorylated human p38 alpha ILVM methyl resonance assignments in ADP and substrate-peptide-bound state

Dual-phosphorylated human p38 alpha ADP and MK2 334/D peptide bound

[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl phosphono hydrogen phosphate

(2S,3R)-2-amino-3-phosphonooxy-butanoic acid

(2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid

Allosteric enhancement of MAP kinase p38α's activity and substrate selectivity by docking interactions.

dual-phosphorylated human p38 alpha (apo)

Corresponding to a.a. 326 400 in human MK2. C-term. 8 a.a. residues are non-natural purification tag.

The Structure Of P38 Mitogen-Activated Protein Kinase In Complex With 4-[3-Methylsulfanylanilino]-6,7- Dimethoxyquinazoline

P38 Map Kinase In Complex With Inhibitor 1

Human P38 Map Kinase In Complex With Birb 796

Crystal Structure Of Map Kinase P38 Complexed To The Docking Site On Its Nuclear Substrate Mef2a

Crystal Structure Of Map Kinase P38 Complexed To The Docking Site On Its Activator Mkk3b

Crystal Structure Of P38 Map Kinase In Complex With A Dihydroquinazolinone Inhibitor

The Structure Of P38 Alpha In Complex With A Pyridinylimidazole Inhibitor

The Structure Of P38 Alpha In Complex With A Dihydropyrido- Pyrimidine Inhibitor

The Structure Of P38 Alpha In Complex With A Dihydroquinolinone

P38 Mitogen-Activated Kinase In Complex With 4-Azaindole Inhibitor

P38 Kinase Crystal Structure In Complex With Small Molecule Inhibitor

Identification Of Novel P38 Alpha Map Kinase Inhibitors Using Fragment-Based Lead Generation.

Structure Of Apo, Unphosphorylated, P38 Mitogen Activated Protein Kinase P38 (P38 Map Kinase) The Mammalian Homologue Of The Ye

Crystal Structure Of P38 Alpha In Complex With A Selective Pyridazine Inhibitor

Crystal Structure Analysis Of Inactive P38 Kinase Domain In Complex With A Monocyclic Pyrazolone Inhibitor

Human P38 Map Kinase In Complex With Inhibitor 1a

Two Classes Of P38alpha Map Kinase Inhibitors Having A Common Diphenylether Core But Exhibiting Divergent Binding Modes

Crystal Structure Of P38 With Triazolopyridine

P38alpha Map Kinase Bound To Pyrazoloamine

Mitogen Activated Protein Kinase P38alpha (D176a+f327s) Activating Mutant Form-A

Mitogen Activated Protein Kinase P38alpha (D176a+f327s) Activating Mutant Form-B

Mitogen Activated Protein Kinase P38alpha (D176a) Activating Mutant

Mitogen Activated Protein Kinase P38alpha (d176a+f327l) Activating Mutant

P38 Kinase Crystal Structure In Complex With Ro3201195

Mutant Mus Musculus P38 Kinase Domain In Complex With Inhibitor Pg-874743

Mutated Map Kinase P38 (Mus Musculus) In Complex With Inhbitor Pg-895449

Mutated Mouse P38 Map Kinase Domain In Complex With Inhibitor Pg-892579

Mutated Map Kinase P38 (mus Musculus) In Complex With Inhbitor Pg-951717

The Structure Of P38alpha In Complex With An Arylpyridazinone

Joint Nmr And X-Ray Refinement Reveals The Structure Of A Novel Dibenzo[a,D]cycloheptenone InhibitorP38 MAP KINASE COMPLEX IN S

A Novel Lipid Binding Site In The P38 Alpha Map Kinase

Crystal Structure Of The P38a-Mapkap Kinase 2 Heterodimer

Crystal Structure Of P38 Complex With 1-(5-Tert-Butyl-2-P- Tolyl-2h-Pyrazol-3-Yl)-3-[4-(6-Morpholin-4-Ylmethyl- Pyridin-3-Yl)na

P38 Alpha Map Kinase Inhibitor Based On Heterobicyclic Scaffolds

Phenylalanine Pyrrolotriazine P38 Alpha Map Kinase Inhibitor Compound 11b

Phenylalanine Pyrrolotriazine P38 Alpha Map Kinase Inhibitor Compound 11j

Crystal Structure Of Human P38alpha Complexed With A Mapk Docking Peptide

Triazolopyridine Inhibitors Of P38 Kinase.

Crystal Structure Of P38 In Complex With 4-Anilino Quinoline Inhibitor

Crystal Structure Of P38 In Complex With Biphenyl Amide Inhibitor

Morpholino Pyrrolotriazine P38 Alpha Map Kinase Inhibitor Compound 30

Morpholino Pyrrolotriazine P38 Alpha Map Kinase Inhibitor Compound 2

P38 Alpha Map Kinase Complexed With Bms-640994

P38 Alpha Map Kinase Complexed With A Benzothiazole Based Inhibitor

Structure Of Map Kinase P38 In Complex With A 1-O-Tolyl-1,2, 3-Triazole-4-Carboxamide

Crystal Structure Of P38 Kinase In Complex With A Biphenyl Amide Inhibitor

P38 Complex With A Phthalazine Inhibitor

Crystal Structure Of P38 Kinase In Complex With A Biaryl Amide Inhibitor

Crystal Structure Of P38 Kinase Bound To Pyrimido-Pyridazinone Inhibitor

P38 Kinase Crystal Structure In Complex With Ro4499

P38 Kinase Crystal Structure In Complex With Ro9552

P38 Kinase Crystal Structure In Complex With Ro7125

P38 Kinase Crystal Structure In Complex With Ro3668

P38 Kinase Crystal Structure In Complex With Ro5634

P38 Kinase Crystal Structure In Complex With R1487

P38 Kinase Crystal Structure In Complex With 6-(2,4- Difluoro-Phenoxy)-2-((S)-2-Methanesulfonyl-1-Methyl- Ethylamino)-8-Methyl-

P38 Kinase Crystal Structure In Complex With 6-(2,4- Difluoro-Phenoxy)-2-((R)-2-Methanesulfonyl-1-Methyl- Ethylamino)-8-Methyl-

P38 Kinase Crystal Structure In Complex With Pamapimod

P38 Kinase Crystal Structure In Complex With 6-(2,4- Difluoro-Phenoxy)-2-Isopropylamino-8-Methyl-8h-Pyrido[2,3- D]pyrimidin-7-O

P38 Kinase Crystal Structure In Complex With 8-Methyl-6-Phenoxy-2- (Tetrahydro-Pyran-4-Ylamino)-8h-Pyrido[2,3-D]pyrimidin-7-One

P38 Kinase Crystal Structure In Complex With 6-(2,4-Difluoro-Phenoxy)- 8-Methyl-2-((R)-1-Methyl-2-Tetrazol-2-Yl-Ethylamino)-8h-

P38 Kinase Crystal Structure In Complex With 4-(5-Methyl-3-Phenyl- Isoxazol-4-Yl)-Pyrimidin-2-Ylamine

P38 Kinase Crystal Structure In Complex With 6-(2,4-Difluoro-Phenoxy)- 8-Methyl-2-((S)-1-Methyl-2-Tetrazol-2-Yl-Ethylamino)-8h-

P38 Kinase Crystal Structure In Complex With Ro6224

P38 Kinase Crystal Structure In Complex With Ro6226

P38 Kinase Crystal Structure In Complex With Ro2530

P38 Kinase Crystal Structure In Complex With 3-(2,6- Dichloro-Phenyl)-7-[4-(2-Diethylamino-Ethoxy)-Phenylamino]- 1-Methyl-3,4-D

P38 Kinase Crystal Structure In Complex With Ro6257

The Structure Of P38alpha In Complex With A Dihydroquinazolinone

Human P38 Map Kinase In Complex With Sb203580

Human P38 Map Kinase In Complex With Rl45

Human P38 Map Kinase In Complex With Sorafenib

Human P38 Map Kinase In Complex With Rl48

Human P38 Map Kinase In Complex With Rl62

Crystal Structure Of P38a Mitogen-Activated Protein Kinase In Complex With A Pyrazolopyridinone Inhibitor

Crystal Structure Of A N-Phenyl-N'-Naphthylurea Analog In Complex With P38 Map Kinase

Crystal Structure Of Human P38alpha Complexed With Sd-0006

Crystal Structure Of Human P38alpha Complexed With Ph-797804

Crystal Structure Of Human P38alpha Complexed With A Pyridinone Compound

Crystal Structure Of Human P38alpha Complexed With A Pyrimidopyridazinone Compound

Human P38 Map Kinase In Complex With Scios-469

Human P38 Map Kinase In Complex With Rl40

Human P38 Map Kinase In Complex With Rl49

Human P38 Map Kinase In Complex With Rl51

Human P38 Map Kinase In Complex With Rl24

Human P38 Map Kinase In Complex With Rl39

Human P38 Map Kinase In Complex With Rl38

Crystal Structure Of Human P38alpha Map Kinase

Crystal Structure Of P38 In Complex With A Biphenylamide Inhibitor

Crystal Structure Of P38a Mitogen-Activated Protein Kinase In Complex With A Pyrazolopyridazine Inhibitor

Human P38 Map Kinase In Complex With An Indole Derivative

Human P38 Map Kinase In Complex With A Benzylpiperazin- Pyrrol

Human P38 Map Kinase In Complex With An Imidazo-Pyridine

Structure Of Inactive Human P38 Map Kinase In Complex With A Thiazole-Urea

P38alpha Bound To Novel Dgf-Out Compound Pf-00215955

P38alpha Bound To Novel Dfg-Out Compound Pf-00416121

Crystal Structure Of Human P38alpha Complexed With A Triazolopyrimidine Compound

Human P38 Map Kinase In Complex With Cp-547632

P38 Alpha Kinase Complexed With A Pyrazolo-Pyrimidine Based Inhibitor

Human P38 Map Kinase In Complex With Dasatinib

Human P38 Map Kinase In Complex With Rl98

Human P38 Map Kinase In Complex With Rl99

Human P38 Map Kinase In Complex With Rl113

Human P38 Map Kinase In Complex With Rl116

Human P38 Map Kinase In Complex With Rl166

Mutagenesis Of P38 Map Kinase Eshtablishes Key Roles Of Phe169 In Function And Structural Dynamics And Reveals A Novel Dfg-Out

Mutagenesis Of P38 Map Kinase Establishes Key Roles Of Phe169 In Function And Structural Dynamics And Reveals A Novel Dfg-Out S

Conformational Plasticity Of P38 Map Kinase Dfg Motif Mutants In Response To Inhibitor Binding

Crystal Structure Of P38 Kinase In Complex With A Pyrrole-2- Carboxamide Inhibitor

P38 Alpha Map Kinase Complexed With Pyrrolotriazine Inhibitor 7k

P38 Alpha Map Kinase Complexed With Pyrrolotriazine Inhibitor 7v

Crystal Structure Of P38 Alpha In Complex With Dp1376

Crystal Structure Of P38 Alpha In Complex With Dp437

Crystal Structure Of P38 Alpha In Complex With Dp802

Crystal Structure Of Phosphorylated P38 Alpha In Complex With Dp802

P38 Alpha Kinase Complexed With A 2-aminothiazol-5-yl-pyrimidine Based Inhibitor

Conformational Plasticity Of P38 Map Kinase Dfg-Motif Mutants In Response To Inhibitor Binding

Conformational Plasticity Of P38 Map Kinase Dfg Mutants In Response To Inhibitor Binding

P38 Alpha Kinase Complexed With A 5-Amino-Pyrazole Based Inhibitor

Crystal Structure Of P38alpha Y323t Active Mutant

Crystal Structure Of P38alpha Y323q Active Mutant

Crystal Structure Of P38alpha Y323r Active Mutant

Crystal Structure Of Y323f Inactive Mutant Of P38alpha Map Kinase

The Third Conformation Of P38a Map Kinase Observed In Phosphorylated P38a And In Solution

Human P38 Map Kinase In Complex With Rl182

Human P38 Map Kinase In Complex With 2-Amino-Phenylamino-Benzophenone

Human P38 Map Kinase In Complex With Skepinone-l

Crystal Structure Of Human P38 Alpha Complexed With A Pyrimidinone Compound

P38 Alpha Kinase Complexed With A Pyrazolo-Triazine Based Inhibitor

Crystal Structure Of P38a Mitogen-Activated Protein Kinase In Complex With A Triazolopyridazinone Inhibitor

Human P38 Map Kinase In Complex With A Benzamide Substituted Benzosuberone

Human P38 Map Kinase In Complex With A Dibenzosuberone Derivative

Human P38 Map Kinase In Complex With Km064

Structural Basis For Kinase Selectivity Of Three Clinical P38alpha Inhibitors

X-Ray Structure Of P38alpha Bound To Tak-715

X-Ray Structure Of P38alpha Bound To Scio-469

X-Ray Structure Of P38alpha Bound To Vx-745

Human P38 Map Kinase In Complex With 2-Amino-Phenylamino- Dibenzosuberone

Human P38 Map Kinase In Complex With Rl87

Human P38 Map Kinase In Complex With Rl163

Structure Of P38a Map Kinase Without Bog

The Crystal Structure Of P38a Map Kinase In Complex With Pia24

Human P38 Map Kinase In Complex With Np-F1 And Rl87

Human P38 Map Kinase In Complex With Np-F2 And Rl87

Human P38 Map Kinase In Complex With Np-F3 And Rl87

Human P38 Map Kinase In Complex With Np-F4 And Rl87

Human P38 Map Kinase In Complex With Np-F5 And Rl87

Human P38 Map Kinase In Complex With Np-F6 And Rl87

Human P38 Map Kinase In Complex With Np-F7 And Rl87

Human P38 Map Kinase In Complex With Np-F11 And Rl87

Human P38 Map Kinase In Complex With Np-F10 And Rl87

P38a Map Kinase Def-pocket Penta Mutant (m194a, L195a, H228a, I229a, Y258a)

Structure Of Map Kinase In Complex With A Docking Peptide

Crystal Structure Of Mitogen-activated Protein Kinase 14 (p38-h5) Complex With 5-(2-chlorophenyl)-n-(5-(cyclopropylcarbamoyl)-2

Crystal Structure Of Mitogen-activated Protein Kinase 14 (p38-h5) Complex With 2-(2-chlorophenyl)-n-(5-(cyclopropylcarbamoyl)-2

Crystal Structure Of Mitogen-activated Protein Kinase 14 (p38-h5) Complex With Ethyl 6-((5-(cyclopropylcarbamoyl)-2-methylpheny

Human P38 Map Kinase In Complex With A Dibenzoxepinone

Structural Basis Of Autoactivation Of P38 Alpha Induced By Tab1 (monoclinic Crystal Form)

Structural Basis Of Autoactivation Of P38 Alpha Induced By Tab1 (tetragonal Crystal Form)

Structural Basis Of Autoactivation Of P38 Alpha Induced By Tab1 (tetragonal Crystal Form With Bound Sulphate)

Ternary Complex Of P38 And Mk2 With A P38 Inhibitor

Alternative spliced variant of p38alpha EXIP [Homo sapiens]

p38 mitogen activated protein kinase [Rattus norvegicus]

p38 mitogen activated protein kinase [Canis lupus familiaris]

mitogen-activated protein kinase 14 [Canis lupus familiaris]

mitogen-activated protein kinase 14 [Ovis aries]

mitogen-activated protein kinase 14 isoform 3 [Mus musculus]

mitogen-activated protein kinase 14 isoform 1 [Mus musculus]

RecName: Full=Mitogen-activated protein kinase 14; Short=MAP kinase 14; Short=MAPK 14; AltName: Full=Mitogen-activated protein

RecName: Full=Mitogen-activated protein kinase 14; Short=MAP kinase 14; Short=MAPK 14; AltName: Full=CRK1; AltName: Full=Mitoge

RecName: Full=Mitogen-activated protein kinase 14; Short=MAP kinase 14; Short=MAPK 14; AltName: Full=Cytokine suppressive anti-

Crystal Structure Of Staurosporine Bound To Map Kap Kinase 2

Crystal Structure Of Adp Bound To Map Kap Kinase 2

Crystal Structure Of A Pyrrolopyridine Inhibitor Bound To Mapkap Kinase-2

Crystal Structure Of An Optimzied Benzothiophene Inhibitor Bound To Mapkap Kinase-2 (Mk-2)

Crystal Structure Of A Benzthiophene Lead Bound To Mapkap Kinase-2 (Mk-2)

mitogen-activated protein kinase-activated protein kinase 2 [synthetic construct]

MAP kinase activated protein kinase-2 [Homo sapiens]

MAP kinase-activated protein kinase 2 [Mus musculus]

MapKap kinase 2 [Cricetulus longicaudatus]

Mapkapk2 protein, partial [Mus musculus]

Mitogen-activated protein kinase-activated protein kinase 2 [Homo sapiens]

MAP kinase-activated protein kinase 2 isoform 2 [Homo sapiens]

PREDICTED: MAP kinase-activated protein kinase 2 isoform 2 [Macaca mulatta]

PREDICTED: MAP kinase-activated protein kinase 2 [Pan troglodytes]

PREDICTED: MAP kinase-activated protein kinase 2 isoform X1 [Bos taurus]

RecName: Full=MAP kinase-activated protein kinase 2; Short=MAPK-activated protein kinase 2; Short=MAPKAP kinase 2; Short=MAPKAP

TPA: MAP kinase-activated protein kinase 2-like [Bos taurus]

Assignments of the ILVM-methyl resonances in p38 were performed by combining
a mutational analysis, J-coupling-based triple resonance experiments
((H)CC(CO)NH, H(CCCO)NH, and HCCH-TOCSY experiments), and an analysis
of the inter-methyl 1H-1H NOE network based on the crystal structures.

Dual-phosphorylated human p38 alpha ADP-bound

Dual-phosphorylated human p38 alpha MK2 334/D peptide bound