Solution NMR structure of the p300 Taz2:ETAD1 complex

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.

The first activation domain of the E2A protein. Corresponds to residues 1-37 of E2A. The N terminal GS is an artifact from protease cleavage.

N terminal GS is remnant of thrombin cleavage site.

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Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax
Brunger, Adams, Clore, Gros, Nilges and Read