Journal of the American Chemical Society
Membrane-proximal domain of a disintegrin and metalloprotease-17 represents the putative molecular switch of its shedding activity operated by protein-disulfide isomerase.

TNF-alpha converting enzyme [Homo sapiens]

TNF-alpha converting enzyme precursor [Homo sapiens]

snake venom-like protease [Homo sapiens]

ADAM metallopeptidase domain 17 [Homo sapiens]

ADAM metallopeptidase domain 17 precursor [Equus caballus]

disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]

PREDICTED: disintegrin and metalloproteinase domain-containing protein 17 isoform X1 [Callithrix jacchus]

PREDICTED: disintegrin and metalloproteinase domain-containing protein 17-like [Macaca mulatta]

PREDICTED: LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 17 [Pongo abelii]

RecName: Full=Disintegrin and metalloproteinase domain-containing protein 17; Short=ADAM 17; AltName: Full=Snake venom-like pro

simulated annealing, torsion angle dynamics

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax