Structure of the influenza AM2-BM2 chimeric channel bound to rimantadine

Information obtained from PDB's Chemical Component Dictionary
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Structural investigation of rimantadine inhibition of the AM2-BM2 chimera channel of influenza viruses.

Residues 18-37 is from M2 of influenza A
Residues 38-52 correspond to 20-34 from BM2 of influenza B

Structure Of The Influenza Am2-Bm2 Chimeric Channel

double labeled protein for NOE experiments

perdeuterated sample for protein-drug NOEs

15% 13C labeled sample for assigning stereospecific methyl groups

Membrane Protein Structures by NMR (MPSbyNMR)

Schwieters, Kuszewski, Tjandra and Clore

Delaglio, Grzesiek, Vuister, Zhu, Pfeifer and Bax