Solution conformation of RNA-bound NELF-E RRM

NELF-E RRM undergoes major structural changes in flexible protein regions on target RNA binding.

TAR(49-57)RNA with the sequence:
UAGGGAACC

RD RNA-binding protein [Rattus norvegicus]

MHC HLA-RD protein, partial [Homo sapiens]

42 kd polypeptide (RD), (first expressed exon) [Mus musculus]

negative elongation factor E [Mus musculus]

negative elongation factor E [Bos taurus]

negative elongation factor E [Sus scrofa]

negative elongation factor E [Rattus norvegicus]

RecName: Full=Negative elongation factor E; Short=NELF-E; AltName: Full=RNA-binding protein RD

TPA: negative elongation factor E [Bos taurus]

Schwieters, Kuszewski, Tjandra and Clore