Solution structure of tandem RRM domains of cytoplasmic polyadenylation element binding protein 4 (CPEB4) in complex with RNA

A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins.

Solution Structure Of Tandem Rrm Domains Of Cytoplasmic Polyadenylation Element Binding Protein 4 (cpeb4) In Free State

unnamed protein product, partial [Tetraodon nigroviridis]

unnamed protein product [Tetraodon nigroviridis]

Cytoplasmic polyadenylation element binding protein 3 [Homo sapiens]

Cytoplasmic polyadenylation element binding protein 4 [Danio rerio]

Cytoplasmic polyadenylation element binding protein 2 [Homo sapiens]

cytoplasmic polyadenylation element-binding protein 3 [Xenopus (Silurana) tropicalis]

cytoplasmic polyadenylation element-binding protein 4 [Rattus norvegicus]

cytoplasmic polyadenylation element-binding protein 2 isoform 2 [Mus musculus]

cytoplasmic polyadenylation element-binding protein 2 isoform C [Homo sapiens]

cytoplasmic polyadenylation element-binding protein 2 isoform D [Homo sapiens]

RecName: Full=Cytoplasmic polyadenylation element-binding protein 4; Short=CPE-BP4; Short=CPE-binding protein 4; Short=hCPEB-4

RecName: Full=Cytoplasmic polyadenylation element-binding protein 3; Short=CPE-BP3; Short=CPE-binding protein 3; Short=CPEB-3

RecName: Full=Cytoplasmic polyadenylation element-binding protein 4; Short=CPE-BP4; Short=CPE-binding protein 4; Short=CPEB-4

RecName: Full=Cytoplasmic polyadenylation element-binding protein 4; Short=CPE-BP4; Short=CPE-binding protein 4; Short=mCPEB-4

RecName: Full=Cytoplasmic polyadenylation element-binding protein 3; Short=CPE-BP3; Short=CPE-binding protein 3; Short=mCPEB-3

TPA: cytoplasmic polyadenylation element binding protein 3 [Bos taurus]

TPA: cytoplasmic polyadenylation element binding protein 4 [Bos taurus]

TPA: cytoplasmic polyadenylation element binding protein 2 isoform 1 [Bos taurus]

TPA: cytoplasmic polyadenylation element binding protein 2 isoform 2 [Bos taurus]

TPA: cytoplasmic polyadenylation element binding protein 2 isoform 3 [Bos taurus]

2D 1H-1H F1-13C-filtered F2-13C-edited NOESY

3D 13C F1-edited, F3-filtered NOESY HSQC

Case, Darden, Cheatham, III, Simmerling, Wang, Duke, Luo, ... and Kollman